{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=allopurinol+or+placebo", "query": { "intervention": "allopurinol or placebo" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=allopurinol+or+placebo&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-29T10:58:24.240Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01399008", "title": "Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout" ], "interventions": [ { "name": "Arhalofenate", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Colchicine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gilead Sciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 100, "start_date": "2011-06", "completion_date": "2012-02", "has_results": true, "last_update_posted_date": "2015-09-18", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 16, "location_summary": "Lincoln, California • Los Angeles, California • Palo Alto, California + 13 more", "locations": [ { "city": "Lincoln", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01399008" }, { "nct_id": "NCT00643123", "title": "Allopurinol Add-on Treatment for Refractory Mania", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder", "Mixed Mania", "Treatment-Resistant Mania" ], "interventions": [ { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 40, "start_date": "2007-09", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2019-05-08", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00643123" }, { "nct_id": "NCT01077284", "title": "Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hyperuricosuria", "Kidney Stones" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 99, "start_date": "2010-02", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2013-02-15", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 28, "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Tucson, Arizona + 25 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01077284" }, { "nct_id": "NCT06276556", "title": "Extension Study of ABP-671 in Participants With Gout", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Gout" ], "interventions": [ { "name": "ABP-671", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Atom Therapeutics Co., Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "19 Years to 75 Years" }, "enrollment_count": 43, "start_date": "2024-04-22", "completion_date": "2024-09-05", "has_results": false, "last_update_posted_date": "2025-07-16", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 33, "location_summary": "Tempe, Arizona • Tucson, Arizona • Anaheim, California + 24 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Brooksville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06276556" }, { "nct_id": "NCT03226899", "title": "A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Gout", "Chronic Kidney Disease (CKD)" ], "interventions": [ { "name": "Lesinurad", "type": "DRUG" }, { "name": "XOI", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "colchicine", "type": "DRUG" }, { "name": "corticosteroids", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ironwood Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 242, "start_date": "2017-07-19", "completion_date": "2019-02-25", "has_results": true, "last_update_posted_date": "2021-11-04", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 70, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Covina, California + 59 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Covina", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03226899" }, { "nct_id": "NCT04040816", "title": "Placebo Controlled, Multiple Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAP-001 in Gout Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout", "Hyperuricemia" ], "interventions": [ { "name": "SAP-001", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shanton Pharma Co., Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 40, "start_date": "2019-01-01", "completion_date": "2020-08-30", "has_results": false, "last_update_posted_date": "2021-11-05", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 6, "location_summary": "Birmingham, Alabama • Anaheim, California • South Miami, Florida + 3 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Anaheim", "state": "California" }, { "city": "South Miami", "state": "Florida" }, { "city": "Meridian", "state": "Idaho" }, { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04040816" }, { "nct_id": "NCT01320722", "title": "Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Renal Function", "Endothelial Function", "Blood Pressure", "Overweight", "Obesity" ], "interventions": [ { "name": "Vitamin D ergocalciferol", "type": "DRUG" }, { "name": "Probenecid", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 242, "start_date": "2011-03", "completion_date": "2015-06", "has_results": true, "last_update_posted_date": "2017-06-29", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01320722" }, { "nct_id": "NCT05818085", "title": "Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Gout" ], "interventions": [ { "name": "ABP-671", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Atom Therapeutics Co., Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "19 Years to 75 Years" }, "enrollment_count": 300, "start_date": "2023-08-11", "completion_date": "2025-03-30", "has_results": false, "last_update_posted_date": "2025-12-22", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 35, "location_summary": "Tempe, Arizona • Tuscon, Arizona • Anaheim, California + 27 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "Tuscon", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Brooksville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05818085" }, { "nct_id": "NCT01637623", "title": "Study of Cardiovascular Disease and Obstructive Sleep Apnea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour)", "Hypertension" ], "interventions": [ { "name": "Losartan", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 87, "start_date": "2012-06", "completion_date": "2015-06", "has_results": true, "last_update_posted_date": "2020-08-14", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 4, "location_summary": "Green Bay, Wisconsin • La Crosse, Wisconsin • Madison, Wisconsin + 1 more", "locations": [ { "city": "Green Bay", "state": "Wisconsin" }, { "city": "La Crosse", "state": "Wisconsin" }, { "city": "Madison", "state": "Wisconsin" }, { "city": "Marshfield", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01637623" }, { "nct_id": "NCT01459796", "title": "Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Gout" ], "interventions": [ { "name": "Rilonacept", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 220, "start_date": "2011-11", "completion_date": "2013-06", "has_results": true, "last_update_posted_date": "2017-07-18", "last_synced_at": "2026-09-29T10:58:24.240Z", "location_count": 74, "location_summary": "Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 71 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Sierra Vista", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01459796" } ] }