{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=aminolevulinic+acid&page=4",
    "query": {
      "intervention": "aminolevulinic acid",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 132,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=aminolevulinic+acid&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=aminolevulinic+acid&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-11T01:27:27.904Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07862647",
      "title": "TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Glioblastom WHO Grade 4",
        "GBM",
        "bGBM",
        "Butterfly GBM",
        "Bihemispheric GBM",
        "Glioblastoma"
      ],
      "interventions": [
        {
          "name": "5-ALA",
          "type": "DRUG"
        },
        {
          "name": "Porphyrin Metabolite Activation (PoMA) with LIDU ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Alpheus Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-10-29",
      "completion_date": "2028-03-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-09",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07862647"
    },
    {
      "nct_id": "NCT01445691",
      "title": "More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Benign Neoplasms, Brain",
        "Brain Cancer",
        "Brain Neoplasms, Benign",
        "Brain Neoplasms, Malignant",
        "Brain Tumor, Primary",
        "Brain Tumor, Recurrent",
        "Brain Tumors",
        "Intracranial Neoplasms",
        "Neoplasms, Brain",
        "Neoplasms, Intracranial",
        "Primary Brain Neoplasms",
        "Primary Malignant Brain Neoplasms",
        "Primary Malignant Brain Tumors",
        "Gliomas",
        "Glioblastoma"
      ],
      "interventions": [
        {
          "name": "5-ALA (Gliolan)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Constantinos Hadjipanayis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-11",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 6,
      "location_summary": "Atlanta, Georgia • Ann Arbor, Michigan • Detroit, Michigan + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01445691"
    },
    {
      "nct_id": "NCT07053852",
      "title": "Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Actinic Keratoses",
        "Photodamage"
      ],
      "interventions": [
        {
          "name": "Ameluz",
          "type": "DRUG"
        },
        {
          "name": "Sciton HEROic",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Sherrif Ibrahim",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2025-06-27",
      "completion_date": "2025-12-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-02",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Victor, New York",
      "locations": [
        {
          "city": "Victor",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07053852"
    },
    {
      "nct_id": "NCT00571974",
      "title": "Treatment of Oral Premalignant Lesions With 5-ALA PDT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Leukoplakia",
        "Erythroplakia"
      ],
      "interventions": [
        {
          "name": "PDL-585, ScleroPLUS laser",
          "type": "DEVICE"
        },
        {
          "name": "5-Aminolevulinic Acid (Levulan KerastickTM)",
          "type": "DRUG"
        },
        {
          "name": "Fluorescence Diagnosis Imaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 29,
      "start_date": "2007-01",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2015-03-24",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00571974"
    },
    {
      "nct_id": "NCT07756671",
      "title": "Photodynamic Therapy For Onychomycosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Onychomycosis of Toenail"
      ],
      "interventions": [
        {
          "name": "ALA 10% gel",
          "type": "DRUG"
        },
        {
          "name": "PDT",
          "type": "DEVICE"
        },
        {
          "name": "Urea",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 5,
      "start_date": "2026-08-10",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-06",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 3,
      "location_summary": "Arlington, Texas • Houston, Texas • Webster, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Webster",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07756671"
    },
    {
      "nct_id": "NCT01403311",
      "title": "A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Glioma"
      ],
      "interventions": [
        {
          "name": "5-Aminolevuline Acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2010-10",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2014-03-26",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01403311"
    },
    {
      "nct_id": "NCT06525571",
      "title": "Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bladder Cancer"
      ],
      "interventions": [
        {
          "name": "Cysview",
          "type": "DRUG"
        },
        {
          "name": "Karl Storz D-Light C Photodynamic Diagnostic (PDD) system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2024-12-20",
      "completion_date": "2028-01-04",
      "has_results": false,
      "last_update_posted_date": "2025-11-18",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06525571"
    },
    {
      "nct_id": "NCT06252727",
      "title": "Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Soft Tissue Sarcoma",
        "Soft Tissue Sarcoma Adult"
      ],
      "interventions": [
        {
          "name": "Aminolevulinic Acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-07",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2024-08-15",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06252727"
    },
    {
      "nct_id": "NCT04055688",
      "title": "Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Brain Tumor",
        "Glioma"
      ],
      "interventions": [
        {
          "name": "Orbeye surgical videomicroscope",
          "type": "DEVICE"
        },
        {
          "name": "5-Aminolevulinic Acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2019-08-15",
      "completion_date": "2021-02-23",
      "has_results": false,
      "last_update_posted_date": "2022-05-31",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04055688"
    },
    {
      "nct_id": "NCT04223570",
      "title": "Portable Measurement of Protoporphyrin IX in the Skin",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Photodynamic Therapy",
        "Protoporphyrin IX"
      ],
      "interventions": [
        {
          "name": "Portable Apple Smart Phone Protoporphyrin IX Spectrometer Camera",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 219,
      "start_date": "2022-12-01",
      "completion_date": "2025-05-20",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-10-11T01:27:27.904Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04223570"
    }
  ]
}