{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=amitriptyline&page=2", "query": { "intervention": "amitriptyline", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=amitriptyline&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-12T01:35:14.594Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00516503", "title": "Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Myeloproliferative Disorders", "Leukemia", "Lymphoma", "Lymphoproliferative Disorder", "Multiple Myeloma and Plasma Cell Neoplasm", "Myelodysplastic Syndromes", "Myelodysplastic/Myeloproliferative Neoplasms", "Neurotoxicity", "Pain", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "baclofen/amitriptyline/ketamine gel", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2008-02", "completion_date": "2010-01", "has_results": true, "last_update_posted_date": "2017-08-24", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 165, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Aurora, Illinois + 104 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Aurora", "state": "Illinois" }, { "city": "Bloomington", "state": "Illinois" }, { "city": "Canton", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00516503" }, { "nct_id": "NCT00564525", "title": "Study of Medication for Functional Abdominal Pain in Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Functional Gastrointestinal Disorders" ], "interventions": [ { "name": "Amitriptyline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "8 Years to 17 Years" }, "enrollment_count": 95, "start_date": "2002-10", "completion_date": "2007-06", "has_results": false, "last_update_posted_date": "2007-11-28", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00564525" }, { "nct_id": "NCT00000793", "title": "A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV Infections", "Peripheral Nervous System Disease" ], "interventions": [ { "name": "Mexiletine hydrochloride", "type": "DRUG" }, { "name": "Benztropine mesylate", "type": "DRUG" }, { "name": "Amitriptyline hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 240, "start_date": null, "completion_date": "1997-10", "has_results": false, "last_update_posted_date": "2021-10-29", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 36, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Diego, California + 23 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000793" }, { "nct_id": "NCT00124306", "title": "Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bladder Diseases", "Interstitial Cystitis" ], "interventions": [ { "name": "Amitriptyline", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 271, "start_date": "2005-02", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2026-01-12", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 9, "location_summary": "Stanford, California • Maywood, Illinois • Iowa City, Iowa + 6 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Maywood", "state": "Illinois" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00124306" }, { "nct_id": "NCT03591458", "title": "Amitriptyline in Treating Hypoglycemia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type1 Diabetes Mellitus", "Hypoglycemia Unawareness" ], "interventions": [ { "name": "Amitriptyline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "21 Years to 60 Years" }, "enrollment_count": 2, "start_date": "2018-08-01", "completion_date": "2019-06-03", "has_results": true, "last_update_posted_date": "2019-07-22", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03591458" }, { "nct_id": "NCT02670161", "title": "Quality Improvement and Practice Based Research in Neurology Using the EMR", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Brain Tumors", "Epilepsy", "Migraine", "Mild Cognitive Impairment", "Concussion", "Multiple Sclerosis", "Neuropathy", "Parkinson's", "Restless Legs Syndrome", "Stroke" ], "interventions": [ { "name": "Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Endeavor Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 3300, "start_date": "2016-05", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2025-08-24", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 1, "location_summary": "Evanston, Illinois", "locations": [ { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02670161" }, { "nct_id": "NCT01206478", "title": "Trial of Amitriptyline for Chronic Oral Food Refusal in Children 9 Months to 8 Years of Age", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Oral Food Refusal" ], "interventions": [ { "name": "Amitriptyline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Megestrol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ann Davis, PhD, MPH, ABPP", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "9 Months", "maximum_age": "8 Years", "sex": "ALL", "summary": "9 Months to 8 Years" }, "enrollment_count": 21, "start_date": "2010-08", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2016-08-15", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 3, "location_summary": "Kansas City, Kansas • New Orleans, Louisiana • Columbus, Ohio", "locations": [ { "city": "Kansas City", "state": "Kansas" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01206478" }, { "nct_id": "NCT02090998", "title": "Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Transformed Migraine", "Chronic Daily Headache" ], "interventions": [ { "name": "SPG Block with 5% Lidocaine gel", "type": "PROCEDURE" }, { "name": "Amitriptyline", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2014-05", "completion_date": "2020-03-16", "has_results": true, "last_update_posted_date": "2026-06-23", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 1, "location_summary": "New Brunswick, New Jersey", "locations": [ { "city": "New Brunswick", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT02090998" }, { "nct_id": "NCT00000817", "title": "The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared With Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections", "Peripheral Nervous System Disease" ], "interventions": [ { "name": "Amitriptyline hydrochloride", "type": "DRUG" }, { "name": "Amitriptyline hydrochloride placebo", "type": "DRUG" }, { "name": "Point acupuncture", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 260, "start_date": "1994-11", "completion_date": "1997-05", "has_results": false, "last_update_posted_date": "2021-11-03", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 11, "location_summary": "San Francisco, California • Denver, Colorado • Washington D.C., District of Columbia + 7 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000817" }, { "nct_id": "NCT02099006", "title": "Novel Topical Therapies for the Treatment of Genital Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Female Genital Diseases" ], "interventions": [ { "name": "Amitriptyline", "type": "DRUG" }, { "name": "Baclofen", "type": "DRUG" }, { "name": "Ketoprofen", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" }, { "name": "Loperamide", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "18 Years to 65 Years · Female only" }, "enrollment_count": 9, "start_date": "2013-11", "completion_date": "2015-06", "has_results": true, "last_update_posted_date": "2016-07-15", "last_synced_at": "2026-09-12T01:35:14.594Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02099006" } ] }