{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=amlodipine+and+olmesartan", "query": { "intervention": "amlodipine and olmesartan" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=amlodipine+and+olmesartan&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-28T13:39:37.267Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00185120", "title": "Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Olmesartan medoxomil", "type": "DRUG" }, { "name": "Hydroclorothiazide", "type": "DRUG" }, { "name": "Benazepril", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 152, "start_date": "2005-09", "completion_date": "2006-09", "has_results": false, "last_update_posted_date": "2012-01-18", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 20, "location_summary": "Mobile, Alabama • Long Beach, California • Los Angeles, California + 17 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Roseville", "state": "California" }, { "city": "Santa Ana", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00185120" }, { "nct_id": "NCT00834600", "title": "Renin Profiling in Selection of Initial Antihypertensive Drug", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "olmesartan, hydrochlorothiazide, amlodipine", "type": "DRUG" }, { "name": "hydrochlorothiazide (HCTZ) or olmesartan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Louis & Rachel Rudin Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "40 Years to 85 Years" }, "enrollment_count": 185, "start_date": "2005-12", "completion_date": "2011-10", "has_results": false, "last_update_posted_date": "2012-04-19", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 5, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" }, { "city": "The Bronx", "state": "New York" }, { "city": "The Bronx", "state": "New York" }, { "city": "The Bronx", "state": "New York" }, { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00834600" }, { "nct_id": "NCT00791258", "title": "A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Who do Not Respond to Single Drug Treatment of Their High Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "amlodipine and olmesartan medoxomil tablets", "type": "DRUG" }, { "name": "hydrochlorothiazide tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 999, "start_date": "2008-11", "completion_date": "2009-09", "has_results": true, "last_update_posted_date": "2019-01-09", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 72, "location_summary": "Birmingham, Alabama • Green Valley, Arizona • Mesa, Arizona + 69 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Green Valley", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00791258" }, { "nct_id": "NCT00654745", "title": "18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 Diabetics", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Type 2 Diabetes", "Hypertension" ], "interventions": [ { "name": "Amlodipine", "type": "DRUG" }, { "name": "amlodipine / olmesartan medoxomil combination", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 207, "start_date": "2008-05", "completion_date": "2009-06", "has_results": true, "last_update_posted_date": "2010-07-13", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 21, "location_summary": "Los Angeles, California • Sylmar, California • Tustin, California + 18 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Sylmar", "state": "California" }, { "city": "Tustin", "state": "California" }, { "city": "Aventura", "state": "Florida" }, { "city": "DeLand", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00654745" }, { "nct_id": "NCT00185133", "title": "Study of Co-administration of Olmesartan Medoxomil Plus Amlodipine in Patients With Mild to Severe Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Olmesartan medoxomil", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1900, "start_date": "2005-05", "completion_date": "2007-01", "has_results": false, "last_update_posted_date": "2018-12-24", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 139, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 136 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Tuscumbia", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00185133" }, { "nct_id": "NCT00649389", "title": "Safety and Efficacy Study of a Triple Combination Therapy in Subjects With Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Olmesartan medoxomil", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 2500, "start_date": "2008-05", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2019-01-09", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 228, "location_summary": "Birmingham, Alabama • Columbiana, Alabama • Gulf Shores, Alabama + 225 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Columbiana", "state": "Alabama" }, { "city": "Gulf Shores", "state": "Alabama" }, { "city": "Hoover", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00649389" }, { "nct_id": "NCT05103332", "title": "Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Indapamide", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" }, { "name": "Olmesartan", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Zilebesiran", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alnylam Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 663, "start_date": "2021-11-05", "completion_date": "2024-09-13", "has_results": true, "last_update_posted_date": "2025-11-03", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 74, "location_summary": "Mesa, Arizona • Tempe, Arizona • Bell Gardens, California + 62 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Bell Gardens", "state": "California" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05103332" }, { "nct_id": "NCT00772499", "title": "Vascular Improvement With Olmesartan Medoxomil Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "olmesartan medoxomil + hydrochlorothiazide + amlodipine + hydralazine if necessary to control blood pressure", "type": "DRUG" }, { "name": "atenolol+ hydrochlorothiazide + amlodipine + hydralazine if necessary to control blood pressure", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 100, "start_date": "2002-11", "completion_date": "2005-07", "has_results": false, "last_update_posted_date": "2008-10-15", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00772499" }, { "nct_id": "NCT01271374", "title": "Changes in Endothelial Function and Biomarkers in African Americans (AA) With Metabolic Syndrome", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "amlodipine and olmesartan", "type": "DRUG" }, { "name": "losartan and HCTZ", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "InVasc Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 80, "start_date": "2010-04", "completion_date": "2011-12", "has_results": false, "last_update_posted_date": "2011-05-05", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 1, "location_summary": "Tucker, Georgia", "locations": [ { "city": "Tucker", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01271374" }, { "nct_id": "NCT04467931", "title": "ACEI or ARB and COVID-19 Severity and Mortality in US Veterans", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertension", "COVID" ], "interventions": [ { "name": "ACEI/ARB", "type": "DRUG" }, { "name": "Non-ACEI/ARB", "type": "DRUG" }, { "name": "ACEI", "type": "DRUG" }, { "name": "ARB", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22213, "start_date": "2020-01-19", "completion_date": "2020-12-31", "has_results": false, "last_update_posted_date": "2021-04-28", "last_synced_at": "2026-09-28T13:39:37.267Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04467931" } ] }