{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=beta-glucan",
    "query": {
      "intervention": "beta-glucan"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 46,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=beta-glucan&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T18:00:59.297Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00002098",
      "title": "Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Lentinan",
          "type": "DRUG"
        },
        {
          "name": "Didanosine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AJI Pharma USA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 50,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Maitland, Florida",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00002098"
    },
    {
      "nct_id": "NCT00682032",
      "title": "The Effect of Beta-glucan in Non-Small Cell Lung Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non Small Cell Lung Cancer"
      ],
      "interventions": [
        {
          "name": "beta-glucan",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2008-10",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2025-01-10",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00682032"
    },
    {
      "nct_id": "NCT00109525",
      "title": "Early Diagnosis of Candidiasis in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infection",
        "Candida",
        "Candidiasis",
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Days",
        "maximum_age": "120 Days",
        "sex": "ALL",
        "summary": "3 Days to 120 Days"
      },
      "enrollment_count": 1500,
      "start_date": "2004-03",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2019-03-22",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 20,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00109525"
    },
    {
      "nct_id": "NCT03925597",
      "title": "Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prebiotics"
      ],
      "interventions": [
        {
          "name": "Fiber cycles ARM 1",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 2",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 3",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 4",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 5",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 7",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 8",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 9",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 10",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 11",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 12",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 13",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 14",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 15",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 16",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 17",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 18",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 19",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 20",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 21",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 22",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 23",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fiber cycles ARM 24",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-01-21",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-26",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03925597"
    },
    {
      "nct_id": "NCT02132403",
      "title": "(PM-01) IMPRIME PGG® With BTH1704 and Gemcitabine for Advanced Pancreatic Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pancreatic Cancer"
      ],
      "interventions": [
        {
          "name": "BTH1704",
          "type": "DRUG"
        },
        {
          "name": "IMPRIME PGG",
          "type": "DRUG"
        },
        {
          "name": "Gemcitabine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2014-08",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-05-01",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02132403"
    },
    {
      "nct_id": "NCT05524688",
      "title": "Beta-glucan and Fatigue in HSCT Survivors",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Autologous Haemopoietic Stem Cell Transplant"
      ],
      "interventions": [
        {
          "name": "Beta-glucan",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 3,
      "start_date": "2023-02-10",
      "completion_date": "2023-08-28",
      "has_results": false,
      "last_update_posted_date": "2023-10-24",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05524688"
    },
    {
      "nct_id": "NCT04513028",
      "title": "Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Melanoma Stage III",
        "Melanoma Stage IV"
      ],
      "interventions": [
        {
          "name": "Beta-Glucan",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Kelly McMasters",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2020-11-03",
      "completion_date": "2027-01-15",
      "has_results": false,
      "last_update_posted_date": "2025-10-30",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04513028"
    },
    {
      "nct_id": "NCT04209075",
      "title": "Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Biomebliss",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Metformin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "10 Years to 25 Years"
      },
      "enrollment_count": 6,
      "start_date": "2020-03-10",
      "completion_date": "2021-07-15",
      "has_results": true,
      "last_update_posted_date": "2022-08-30",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04209075"
    },
    {
      "nct_id": "NCT01829373",
      "title": "Lung Cancer Vaccine Plus Oral Dietary Supplement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "vaccine 1650-G",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Edward Hirschowitz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2011-10",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2013-04-11",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01829373"
    },
    {
      "nct_id": "NCT02939547",
      "title": "Study of the Pharmacokinetics of Trappsol and Effects on Potential Biomarkers of Niemann-Pick C1 (NPC1)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Niemann-Pick Disease, Type C1"
      ],
      "interventions": [
        {
          "name": "Hydroxypropyl-beta-cyclodextrin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cyclo Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2017-10-11",
      "completion_date": "2020-02-10",
      "has_results": false,
      "last_update_posted_date": "2021-02-21",
      "last_synced_at": "2026-09-03T18:00:59.297Z",
      "location_count": 2,
      "location_summary": "Oakland, California • Morristown, New Jersey",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Morristown",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02939547"
    }
  ]
}