{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=brain+natriuretic+peptide", "query": { "intervention": "brain natriuretic peptide" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 87, "total_pages": 9, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=brain+natriuretic+peptide&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-22T20:36:40.763Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01544998", "title": "Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Congestive Heart Failure" ], "interventions": [ { "name": "Nesiritide", "type": "DRUG" }, { "name": "Tadalafil", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Saline load", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "21 Years to 90 Years" }, "enrollment_count": 43, "start_date": "2012-02", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2018-03-22", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01544998" }, { "nct_id": "NCT00953472", "title": "B-type Natriuretic Peptide (BNP) in Human Hypertension", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension Stage 1" ], "interventions": [ { "name": "brain natriuretic peptide", "type": "DRUG" }, { "name": "no-added salt diet", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 8, "start_date": "2009-02", "completion_date": "2011-04", "has_results": false, "last_update_posted_date": "2011-10-12", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00953472" }, { "nct_id": "NCT00145873", "title": "Nesiritide in Chronic Heart Failure", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "nesiritide, continuous infusion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2003-08", "completion_date": "2006-09", "has_results": false, "last_update_posted_date": "2013-10-08", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00145873" }, { "nct_id": "NCT00348556", "title": "Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Cardiorenal Syndrome" ], "interventions": [ { "name": "Nesiritide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Horng Chen", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 4, "start_date": "2005-12", "completion_date": "2010-03", "has_results": true, "last_update_posted_date": "2017-11-06", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00348556" }, { "nct_id": "NCT00409578", "title": "Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Post Acute Coronary Syndrome", "Myocardial Ischemia" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Aliskiren 300 mg", "type": "DRUG" }, { "name": "Valsartan 320 mg", "type": "DRUG" }, { "name": "Aliskiren/valsartan 300/320 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1101, "start_date": "2007-02", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2011-04-19", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Investigative Site, New Jersey", "locations": [ { "city": "Investigative Site", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00409578" }, { "nct_id": "NCT00709163", "title": "Nesiritide - Dilated Cardiomyopathy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dilated Cardiomyopathy" ], "interventions": [ { "name": "Nesiritide", "type": "DRUG" }, { "name": "5% Dextrose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 20, "start_date": "2003-12", "completion_date": "2005-11", "has_results": false, "last_update_posted_date": "2008-07-03", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00709163" }, { "nct_id": "NCT03064360", "title": "Early Prediction of Major Adverse Cardiovascular Events Using Remote Monitoring", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Ischemic Heart Disease" ], "interventions": [ { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Patient Activity", "type": "DEVICE" }, { "name": "Questionnaires", "type": "BEHAVIORAL" } ], "intervention_types": [ "OTHER", "DEVICE", "BEHAVIORAL" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "105 Years", "sex": "ALL", "summary": "18 Years to 105 Years" }, "enrollment_count": 200, "start_date": "2017-02-13", "completion_date": "2020-01-01", "has_results": false, "last_update_posted_date": "2020-07-21", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03064360" }, { "nct_id": "NCT00567437", "title": "Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Aortic Stenosis" ], "interventions": [ { "name": "NT-pro-BNP levels", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 110, "start_date": "2007-12", "completion_date": "2008-12", "has_results": false, "last_update_posted_date": "2012-10-24", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00567437" }, { "nct_id": "NCT00453622", "title": "RISK Stratification Using a Combination of Cardiac Troponin T and Brain Natriuretic Peptide in Patients Receiving CRT-D", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "Cardiac Resynchronization Therapy-Defibrillator", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 222, "start_date": "2005-11", "completion_date": "2012-08", "has_results": false, "last_update_posted_date": "2019-02-04", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00453622" }, { "nct_id": "NCT00252200", "title": "BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Acute Kidney Failure" ], "interventions": [ { "name": "Neseritide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2003-03", "completion_date": "2007-10", "has_results": false, "last_update_posted_date": "2009-09-23", "last_synced_at": "2026-09-22T20:36:40.763Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00252200" } ] }