{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=bupivacaine+and+epinephrine&page=2", "query": { "intervention": "bupivacaine and epinephrine", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 160, "total_pages": 16, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=bupivacaine+and+epinephrine&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=bupivacaine+and+epinephrine&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-09T08:03:17.122Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01583166", "title": "Voiding Function After Mid-Urethral Slings With and Without Local Anesthetic: Randomized Controlled Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stress Urinary Incontinence" ], "interventions": [ { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Massachusetts, Worcester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 90, "start_date": "2012-03", "completion_date": "2016-05", "has_results": true, "last_update_posted_date": "2018-11-28", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Worcester, Massachusetts", "locations": [ { "city": "Worcester", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01583166" }, { "nct_id": "NCT04284930", "title": "Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain, Postoperative" ], "interventions": [ { "name": "Depobupivacaine", "type": "DRUG" }, { "name": "OnQ pump", "type": "DRUG" }, { "name": "0.25% Bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 21, "start_date": "2016-02", "completion_date": "2017-11", "has_results": true, "last_update_posted_date": "2021-01-07", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04284930" }, { "nct_id": "NCT00398866", "title": "A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Osteoarthritis" ], "interventions": [ { "name": "Synvisc (Hylan G-F20; hyaluronan injection)", "type": "DRUG" }, { "name": "Bupivicaine (local anesthesia injection)", "type": "DRUG" }, { "name": "Kenalog (triamcinolone; corticosteroid injection)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hospital for Special Surgery, New York", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "95 Years", "sex": "ALL", "summary": "45 Years to 95 Years" }, "enrollment_count": 200, "start_date": "2006-08", "completion_date": "2013-03", "has_results": true, "last_update_posted_date": "2017-07-07", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00398866" }, { "nct_id": "NCT02365727", "title": "Exparel vs Exparel Plus ACB in TKAs", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Knee Osteoarthritis" ], "interventions": [ { "name": "Liposomal bupivacaine", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Clonidine", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Hawkins Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 0, "start_date": "2015-04", "completion_date": "2015-08", "has_results": false, "last_update_posted_date": "2016-01-14", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Greenville, South Carolina", "locations": [ { "city": "Greenville", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02365727" }, { "nct_id": "NCT02296099", "title": "Trial Liposomal Bupivacaine Following Retropubic Suburethral Sling for Stress Urinary Incontinence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Urinary Incontinence, Stress" ], "interventions": [ { "name": "liposomal bupivacaine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "TriHealth Inc.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 114, "start_date": "2014-11", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2018-08-16", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02296099" }, { "nct_id": "NCT06471348", "title": "Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Post Operative Pain", "Spinal Fusion" ], "interventions": [ { "name": "Bupivacaine liposome injectable suspension", "type": "DRUG" }, { "name": "Bupivacaine Hydrochloride and Epinephrine Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 128, "start_date": "2025-08-15", "completion_date": "2028-08-31", "has_results": false, "last_update_posted_date": "2025-10-22", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06471348" }, { "nct_id": "NCT06354023", "title": "Human Growth Hormone Injections in the Knee Joint to Treat Osteoarthritis", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Osteoarthritis, Knee" ], "interventions": [ { "name": "Recombinant human growth hormone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "John Sledge", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "72 Years", "sex": "ALL", "summary": "18 Years to 72 Years" }, "enrollment_count": 23, "start_date": "2025-02-08", "completion_date": "2026-02-08", "has_results": false, "last_update_posted_date": "2024-10-04", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Santa Monica, California", "locations": [ { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06354023" }, { "nct_id": "NCT02741713", "title": "Analgesic Benefit of PECS Blocks for Biceps Tenodesis Shoulder Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Biceps Tendonitis" ], "interventions": [ { "name": "PECS \"Pectoralis\" 1 and 2 Blocks", "type": "PROCEDURE" }, { "name": "Interscalene Block", "type": "PROCEDURE" }, { "name": "Sham Block", "type": "PROCEDURE" }, { "name": "Solution for Injection in Interscalene Block", "type": "DRUG" }, { "name": "Solution for Injection in Sham Block", "type": "DRUG" }, { "name": "Solution for Injection PECS Blocks", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2016-04", "completion_date": "2017-06-29", "has_results": true, "last_update_posted_date": "2018-08-27", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02741713" }, { "nct_id": "NCT01206608", "title": "Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects Undergoing Augmentation Mammoplasty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "SKY0402 + bupivacaine HCl", "type": "DRUG" }, { "name": "Mid-dose SKY0402 + bupivacaine HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pacira Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "FEMALE", "summary": "18 Years to 40 Years · Female only" }, "enrollment_count": 40, "start_date": "2008-03", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2021-03-02", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01206608" }, { "nct_id": "NCT01243112", "title": "Effectiveness Study of Different Local Anesthetic Mixtures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain" ], "interventions": [ { "name": "1% Lidocaine with Epinephrine (1:100,000)", "type": "DRUG" }, { "name": "0.25% Bupivacaine with Epinephrine (1:200,000)", "type": "DRUG" }, { "name": "0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000)", "type": "DRUG" }, { "name": "1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Scott and White Hospital & Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 25, "start_date": "2010-05", "completion_date": "2010-09", "has_results": true, "last_update_posted_date": "2011-12-02", "last_synced_at": "2026-10-09T08:03:17.122Z", "location_count": 1, "location_summary": "Temple, Texas", "locations": [ { "city": "Temple", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01243112" } ] }