{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=bupropion+%2B+lozenge&page=2", "query": { "intervention": "bupropion + lozenge", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 26, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=bupropion+%2B+lozenge&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=bupropion+%2B+lozenge&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T13:36:41.603Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01576640", "title": "Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Nicotine Dependence", "Schizophrenia" ], "interventions": [ { "name": "NRT", "type": "DRUG" }, { "name": "Bupropion SR 150mg bid", "type": "DRUG" }, { "name": "Relapse Prevention-Oriented Cognitive Behavioral Therapy", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 17, "start_date": "2005-12", "completion_date": "2007-10", "has_results": false, "last_update_posted_date": "2015-05-21", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01576640" }, { "nct_id": "NCT01309217", "title": "Dissemination of Tobacco Tactics for Hospitalized Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Tobacco Tactics Intervention", "type": "BEHAVIORAL" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1528, "start_date": "2011-07", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2014-11-18", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 6, "location_summary": "Grand Rapids, Michigan • Livonia, Michigan • Muskegon, Michigan + 2 more", "locations": [ { "city": "Grand Rapids", "state": "Michigan" }, { "city": "Livonia", "state": "Michigan" }, { "city": "Muskegon", "state": "Michigan" }, { "city": "Muskegon", "state": "Michigan" }, { "city": "Oakland", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01309217" }, { "nct_id": "NCT02873754", "title": "Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "Cognitive Behavioral Counseling", "type": "BEHAVIORAL" }, { "name": "Mobile Contingency Management", "type": "BEHAVIORAL" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Transdermal nicotine patch", "type": "DRUG" }, { "name": "Nicotine polacrilex", "type": "DRUG" }, { "name": "Nicotine lozenge", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 11, "start_date": "2017-01", "completion_date": "2017-07", "has_results": true, "last_update_posted_date": "2018-07-13", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02873754" }, { "nct_id": "NCT04501016", "title": "A Stepped Care Approach to Treating Tobacco Use in Rural Veterans", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Tobacco Cessation" ], "interventions": [ { "name": "Tailored behavioral counseling", "type": "BEHAVIORAL" }, { "name": "Tobacco cessation pharmacotherapy", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Iowa City Veterans Affairs Medical Center", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 100, "start_date": "2020-09", "completion_date": "2023-09", "has_results": false, "last_update_posted_date": "2020-08-06", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT04501016" }, { "nct_id": "NCT00320697", "title": "Smoking Relapse Prevention in Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder", "Smokers" ], "interventions": [ { "name": "bupropion + nicotine patch + nicotine gum or lozenges", "type": "DRUG" }, { "name": "Placebo pill + placebo patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "North Suffolk Mental Health Association", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 25, "start_date": "2006-04", "completion_date": "2009-08", "has_results": false, "last_update_posted_date": "2016-09-27", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00320697" }, { "nct_id": "NCT02420015", "title": "Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia", "Cigarette Smoking" ], "interventions": [ { "name": "Nicotine replacement therapy", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "cognitive-behavioral smoking cessation counseling", "type": "BEHAVIORAL" }, { "name": "Mobile Contingency Management", "type": "BEHAVIORAL" }, { "name": "Stay Quit Coach", "type": "BEHAVIORAL" }, { "name": "SMS text messaging", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 35, "start_date": "2017-03-27", "completion_date": "2019-01-24", "has_results": true, "last_update_posted_date": "2019-07-10", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02420015" }, { "nct_id": "NCT03670316", "title": "Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "HIV", "AIDS", "Smoking Cessation" ], "interventions": [ { "name": "Algorithm Treatment", "type": "DRUG" }, { "name": "Quitline only", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 371, "start_date": "2020-08-17", "completion_date": "2025-06-30", "has_results": true, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT03670316" }, { "nct_id": "NCT01592695", "title": "Tailored Tobacco Quitline for Rural Veterans", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cigarette Smoking" ], "interventions": [ { "name": "Nicotine replacement therapy - transdermal nicotine patch", "type": "DRUG" }, { "name": "Tailored behavioral intervention", "type": "BEHAVIORAL" }, { "name": "Tobacco quit line referral", "type": "BEHAVIORAL" }, { "name": "Nicotine replacement therapy - nicotine gum", "type": "DRUG" }, { "name": "Nicotine replacement therapy - nicotine lozenge", "type": "DRUG" }, { "name": "Bupropion Sustained Release", "type": "DRUG" }, { "name": "Varenicline", "type": "DRUG" }, { "name": "Combination pharmacotherapy - transdermal nicotine patch + nicotine gum", "type": "DRUG" }, { "name": "Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge", "type": "DRUG" }, { "name": "Combination pharmacotherapy - transdermal nicotine patch + bupropion", "type": "DRUG" }, { "name": "Alcohol use risk reduction", "type": "BEHAVIORAL" }, { "name": "Behavioral activation for the treatment of depression", "type": "BEHAVIORAL" }, { "name": "Behavioral management of post-cessation weight gain", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Iowa City Veterans Affairs Medical Center", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 63, "start_date": "2012-06", "completion_date": "2013-06", "has_results": true, "last_update_posted_date": "2019-08-02", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT01592695" }, { "nct_id": "NCT04604509", "title": "Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cigarette Smoking-Related Carcinoma" ], "interventions": [ { "name": "Bupropion Hydrochloride Controlled-release", "type": "DRUG" }, { "name": "Nicotine Replacement", "type": "DRUG" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Tobacco Cessation Counseling", "type": "OTHER" }, { "name": "Varenicline", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2010, "start_date": "2020-08-04", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2026-05-04", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04604509" }, { "nct_id": "NCT07714200", "title": "Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use Disorder" ], "interventions": [ { "name": "Cognitive Behavioral Therapy for Smoking Cessation", "type": "BEHAVIORAL" }, { "name": "Nicotine Replacement Therapy", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Varenicline", "type": "DRUG" }, { "name": "Mobile Contingency Management", "type": "BEHAVIORAL" }, { "name": "Clinic-Based Smoking Cessation Counseling", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2027-03-01", "completion_date": "2030-09-01", "has_results": false, "last_update_posted_date": "2026-07-20", "last_synced_at": "2026-10-04T13:36:41.603Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07714200" } ] }