{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cariprazine", "query": { "intervention": "cariprazine" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 39, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cariprazine&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-11T14:01:27.465Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01058096", "title": "Safety and Efficacy of Cariprazine for Mania", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder", "Mania" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 323, "start_date": "2010-02", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2017-04-17", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 10, "location_summary": "Long Beach, California • Riverside, California • San Diego, California + 7 more", "locations": [ { "city": "Long Beach", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Lake Charles", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01058096" }, { "nct_id": "NCT01469377", "title": "Safety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Cariprazine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 819, "start_date": "2011-12-15", "completion_date": "2013-12-12", "has_results": true, "last_update_posted_date": "2018-05-01", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 39, "location_summary": "Garden Grove, California • National City, California • Oceanside, California + 34 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "National City", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01469377" }, { "nct_id": "NCT04965272", "title": "A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepressant Therapies (ADTs) Compared to Placebo in Adult Participants With Generalized Anxiety Disorder (GAD) Who Have Had an Inadequate Response to ADTs Alone", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Generalized Anxiety Disorder" ], "interventions": [ { "name": "Cariprazine 0.75 mg/day", "type": "DRUG" }, { "name": "Cariprazine 1.5 mg/day", "type": "DRUG" }, { "name": "Cariprazine 3.0 mg/day", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2021-08-18", "completion_date": "2021-08-24", "has_results": false, "last_update_posted_date": "2022-04-12", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 36, "location_summary": "Little Rock, Arkansas • Colton, California • Costa Mesa, California + 29 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Colton", "state": "California" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Culver City", "state": "California" }, { "city": "Encino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04965272" }, { "nct_id": "NCT06433635", "title": "Sequential Multiple Assignment Randomized Trial for Bipolar Depression", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar I Disorder", "Depression" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Aripiprazole/Escitalopram combination", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Lurasidone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 2726, "start_date": "2024-10-01", "completion_date": "2030-02-28", "has_results": false, "last_update_posted_date": "2025-12-16", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 17, "location_summary": "Birmingham, Alabama • Bloomington, Indiana • Baltimore, Maryland + 13 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Bloomington", "state": "Indiana" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Belmont", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06433635" }, { "nct_id": "NCT05439616", "title": "Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Autism Spectrum Disorder" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "5 Years to 17 Years" }, "enrollment_count": 161, "start_date": "2022-07-07", "completion_date": "2024-10-04", "has_results": false, "last_update_posted_date": "2025-04-04", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 34, "location_summary": "Anaheim, California • Imperial, California • Orange, California + 28 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Imperial", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Upland", "state": "California" }, { "city": "Doral", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05439616" }, { "nct_id": "NCT03739203", "title": "The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Antidepressant Therapy (ADT)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 752, "start_date": "2018-11-10", "completion_date": "2021-09-06", "has_results": true, "last_update_posted_date": "2022-09-21", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 58, "location_summary": "Dothan, Alabama • Little Rock, Arkansas • Anaheim, California + 50 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Colton", "state": "California" }, { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03739203" }, { "nct_id": "NCT05741502", "title": "An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Treatment-resistant Schizophrenia" ], "interventions": [ { "name": "Clozapine", "type": "DRUG" }, { "name": "Antipsychotics,Other (non-Clozapine)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 5, "start_date": "2023-08-16", "completion_date": "2026-01-23", "has_results": false, "last_update_posted_date": "2026-02-25", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05741502" }, { "nct_id": "NCT04578756", "title": "Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Schizophrenia", "Bipolar I Disorder", "Autism Spectrum Disorder (ASD)" ], "interventions": [ { "name": "Cariprazine Flexible Dose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "5 Years to 17 Years" }, "enrollment_count": 310, "start_date": "2021-02-01", "completion_date": "2025-10-06", "has_results": false, "last_update_posted_date": "2025-10-27", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 40, "location_summary": "Dothan, Alabama • Bentonville, Arkansas • Anaheim, California + 31 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Bentonville", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04578756" }, { "nct_id": "NCT03738215", "title": "Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 759, "start_date": "2018-11-09", "completion_date": "2021-09-30", "has_results": true, "last_update_posted_date": "2022-10-25", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 65, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Rogers, Arkansas + 59 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03738215" }, { "nct_id": "NCT04382885", "title": "Cariprazine Pediatric ASD PK Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Autism Spectrum Disorder" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "5 Years to 17 Years" }, "enrollment_count": 24, "start_date": "2020-06-26", "completion_date": "2021-12-10", "has_results": false, "last_update_posted_date": "2022-04-12", "last_synced_at": "2026-09-11T14:01:27.465Z", "location_count": 3, "location_summary": "Orange, California • Atlanta, Georgia • Decatur, Georgia", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Decatur", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04382885" } ] }