{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cefuroxime", "query": { "intervention": "cefuroxime" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cefuroxime&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T23:59:27.919Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03014687", "title": "Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Antibiotics", "Pituitary Adenoma" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "84 Years", "sex": "ALL", "summary": "18 Years to 84 Years" }, "enrollment_count": 116, "start_date": "2017-07-01", "completion_date": "2019-07", "has_results": false, "last_update_posted_date": "2018-08-15", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03014687" }, { "nct_id": "NCT00492973", "title": "Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Osteoarthritis", "Post-traumatic; Arthrosis" ], "interventions": [ { "name": "methylprednisolone acetate", "type": "DRUG" }, { "name": "active comparator", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New Lexington Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "95 Years", "sex": "ALL", "summary": "18 Years to 95 Years" }, "enrollment_count": 101, "start_date": "2006-03", "completion_date": "2008-02", "has_results": true, "last_update_posted_date": "2013-12-19", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT00492973" }, { "nct_id": "NCT07492134", "title": "APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Uncomplicated Diverticulitis" ], "interventions": [ { "name": "Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Metronidazole", "type": "DRUG" }, { "name": "Cefuroxime", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 100, "start_date": "2026-07-07", "completion_date": "2028-10-01", "has_results": false, "last_update_posted_date": "2026-07-08", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT07492134" }, { "nct_id": "NCT06406114", "title": "Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Drug Allergy", "Cephalosporin Allergy", "Drug Hypersensitivity", "Antibiotic Allergy", "Beta Lactam Adverse Reaction", "Drug-Induced Anaphylaxis", "Cephalosporin Reaction" ], "interventions": [ { "name": "Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing", "type": "DRUG" }, { "name": "Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge", "type": "DRUG" }, { "name": "Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge", "type": "DRUG" }, { "name": "Dissimilar cephalosporin (ceftriaxone or cefazolin) antibiotic double-blind placebo-controlled drug challenge", "type": "DRUG" }, { "name": "Amoxicillin double-blind placebo-controlled drug challenge", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 300, "start_date": "2025-05-05", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2026-05-26", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 6, "location_summary": "Scottsdale, Arizona • San Francisco, California • Boston, Massachusetts + 3 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "San Francisco", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Rochester", "state": "New York" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT06406114" }, { "nct_id": "NCT01659866", "title": "Antibiotic Prophylaxis for Transrectal Prostate Biopsy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Infection" ], "interventions": [ { "name": "Ciprofloxacin", "type": "DRUG" }, { "name": "trimethoprim-sulfamethoxazole", "type": "DRUG" }, { "name": "cefuroxime", "type": "DRUG" }, { "name": "ceftriaxone", "type": "DRUG" }, { "name": "gentamicin", "type": "DRUG" }, { "name": "amikacin", "type": "DRUG" }, { "name": "aztreonam", "type": "DRUG" }, { "name": "imipenem", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": "90 Years", "sex": "MALE", "summary": "30 Years to 90 Years · Male only" }, "enrollment_count": 563, "start_date": "2012-08", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2019-06-25", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01659866" }, { "nct_id": "NCT00000752", "title": "Preventing Frequent Sinus Infections in HIV-Infected Patients", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV Infections", "Sinusitis" ], "interventions": [ { "name": "Pseudoephedrine hydrochloride", "type": "DRUG" }, { "name": "Guaifenesin", "type": "DRUG" }, { "name": "Cefuroxime axetil", "type": "DRUG" }, { "name": "Beclomethasone dipropionate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 0, "start_date": null, "completion_date": "1993-02", "has_results": false, "last_update_posted_date": "2021-10-28", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 10, "location_summary": "San Diego, California • San Francisco, California • The Bronx, New York + 1 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "The Bronx", "state": "New York" }, { "city": "The Bronx", "state": "New York" }, { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000752" }, { "nct_id": "NCT00132938", "title": "PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Chronic Bronchitis" ], "interventions": [ { "name": "telithromycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": 5660, "start_date": "2004-01", "completion_date": "2006-05", "has_results": false, "last_update_posted_date": "2011-06-08", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00132938" }, { "nct_id": "NCT02800785", "title": "The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Appendicitis" ], "interventions": [ { "name": "Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin", "type": "DRUG" }, { "name": "Appendectomy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1552, "start_date": "2016-05", "completion_date": "2021-09-01", "has_results": true, "last_update_posted_date": "2023-05-06", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 25, "location_summary": "Sylmar, California • Torrance, California • Aurora, Colorado + 14 more", "locations": [ { "city": "Sylmar", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT02800785" }, { "nct_id": "NCT02297815", "title": "Comparative Effectiveness of Antibiotics for Respiratory Infections", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Acute Otitis Media", "Acute Sinusitis", "Group A Streptococcal Pharyngitis" ], "interventions": [ { "name": "Broad-spectrum antibiotics", "type": "DRUG" }, { "name": "Narrow-spectrum antibiotics", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Months to 12 Years" }, "enrollment_count": 2472, "start_date": "2014-01", "completion_date": "2016-04", "has_results": true, "last_update_posted_date": "2019-07-08", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02297815" }, { "nct_id": "NCT01434173", "title": "Risk of Acute Liver Injury in Users of Antimicrobials", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Drug-Induced Liver Injury" ], "interventions": [ { "name": "Moxifloxacin (Avelox, BAY12-8039)", "type": "DRUG" }, { "name": "Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1299056, "start_date": "2001-07", "completion_date": "2009-03", "has_results": false, "last_update_posted_date": "2014-07-08", "last_synced_at": "2026-09-02T23:59:27.919Z", "location_count": 1, "location_summary": "Many Locations, Delaware", "locations": [ { "city": "Many Locations", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT01434173" } ] }