{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cetylpyridinium+chloride+Mouthwash",
    "query": {
      "intervention": "cetylpyridinium chloride Mouthwash"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cetylpyridinium+chloride+Mouthwash&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T04:00:48.585Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04748783",
      "title": "Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "COVID19",
        "Coronavirus Infection",
        "SARS CoV-2 Infection"
      ],
      "interventions": [
        {
          "name": "Water",
          "type": "OTHER"
        },
        {
          "name": "Peroxyl",
          "type": "OTHER"
        },
        {
          "name": "Periogard",
          "type": "DRUG"
        },
        {
          "name": "Colgate Total Zero",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 2,
      "start_date": "2021-03-26",
      "completion_date": "2021-04-07",
      "has_results": true,
      "last_update_posted_date": "2022-02-16",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04748783"
    },
    {
      "nct_id": "NCT06933368",
      "title": "A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Crest Cavity Protection Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Experimental Mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2025-04-21",
      "completion_date": "2025-08-14",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06933368"
    },
    {
      "nct_id": "NCT07619729",
      "title": "Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetes Type 2",
        "Periodontal Disease",
        "Caries"
      ],
      "interventions": [
        {
          "name": "Diabetes Oral Health Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stannous Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2026-05-26",
      "completion_date": "2028-01-02",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Long Island City, New York",
      "locations": [
        {
          "city": "Long Island City",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07619729"
    },
    {
      "nct_id": "NCT02002442",
      "title": "Dental Implants and Mouth Rinse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Reduction in Bacterial Counts Through the Use of Mouthwash"
      ],
      "interventions": [
        {
          "name": "Mouthwash",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2013-11",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2018-12-05",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02002442"
    },
    {
      "nct_id": "NCT02366689",
      "title": "Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Triclosan/fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "stannous fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "fluoride only toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Cetylpyridinium chloride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Fluoride only mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 179,
      "start_date": "2014-06",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-03-30",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Cedar Knolls, New Jersey",
      "locations": [
        {
          "city": "Cedar Knolls",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02366689"
    },
    {
      "nct_id": "NCT07211061",
      "title": "A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Sodium Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "electric toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "Cetylpyridinium Chloride (CPC)",
          "type": "DRUG"
        },
        {
          "name": "manual toothbrush",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 69,
      "start_date": "2011-09-21",
      "completion_date": "2011-11-10",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07211061"
    },
    {
      "nct_id": "NCT06660069",
      "title": "A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste)",
          "type": "DRUG"
        },
        {
          "name": "CPC Mouthwash (Parodontax Active Gum Health Mouthwash)",
          "type": "DRUG"
        },
        {
          "name": "Regular Fluoride Toothpaste (Crest Cavity Protection)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 199,
      "start_date": "2024-11-18",
      "completion_date": "2025-03-11",
      "has_results": true,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06660069"
    },
    {
      "nct_id": "NCT04584684",
      "title": "Mouth Rinses for Inactivation of COVID-19",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Covid19",
        "Coronavirus Infection",
        "SARS-CoV-2 Infection"
      ],
      "interventions": [
        {
          "name": "0.9% w/v NaCL Saline",
          "type": "OTHER"
        },
        {
          "name": "1.5% w/v Hydrogen Peroxide",
          "type": "DRUG"
        },
        {
          "name": "0.12% Chlorohexidine Gluconate",
          "type": "DRUG"
        },
        {
          "name": "27% Ethanol plus essential oils",
          "type": "DRUG"
        },
        {
          "name": "0.5% w/v Povidone-iodide",
          "type": "DRUG"
        },
        {
          "name": "0.075% Cetylpyridinium Chloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 128,
      "start_date": "2020-12-18",
      "completion_date": "2021-10-21",
      "has_results": true,
      "last_update_posted_date": "2024-03-25",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04584684"
    },
    {
      "nct_id": "NCT06244303",
      "title": "Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gingivitis",
        "Plaque"
      ],
      "interventions": [
        {
          "name": "manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F)",
          "type": "DRUG"
        },
        {
          "name": "manual toothbrush + Colgate dental cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 82,
      "start_date": "2024-01-22",
      "completion_date": "2024-04-16",
      "has_results": false,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Costa Mesa, California",
      "locations": [
        {
          "city": "Costa Mesa",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06244303"
    },
    {
      "nct_id": "NCT05178173",
      "title": "Efficacy of Oral Rinses for Inactivation of COVID-19 (MOR2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COVID-19",
        "Coronavirus Infection",
        "SARS CoV 2 Infection"
      ],
      "interventions": [
        {
          "name": "Placebo Comparator: Sterile Water",
          "type": "OTHER"
        },
        {
          "name": "27% Ethanol plus essential oils",
          "type": "OTHER"
        },
        {
          "name": "0.075% Cetylpyridinium Chloride",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 230,
      "start_date": "2022-01-20",
      "completion_date": "2023-07-12",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-10-09T04:00:48.585Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05178173"
    }
  ]
}