{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=clinical+Whole+Genome+Sequencing&page=2", "query": { "intervention": "clinical Whole Genome Sequencing", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 41, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=clinical+Whole+Genome+Sequencing&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=clinical+Whole+Genome+Sequencing&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T13:36:53.129Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03525431", "title": "Clinical Utility of Pediatric Whole Exome Sequencing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Encephalopathy", "Birth Defect", "Intellectual Disability", "Multiple Congenital Anomaly", "Metabolic Disease", "Epilepsy", "Neuro-Degenerative Disease", "Cerebral Palsy", "Developmental Delay", "Developmental Defect" ], "interventions": [ { "name": "Whole Exome Sequencing", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "25 Years", "sex": "ALL", "summary": "Up to 25 Years" }, "enrollment_count": 529, "start_date": "2017-08-01", "completion_date": "2022-05-13", "has_results": true, "last_update_posted_date": "2023-07-18", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 4, "location_summary": "Fresno, California • Oakland, California • San Francisco, California", "locations": [ { "city": "Fresno", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03525431" }, { "nct_id": "NCT02699190", "title": "LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Leukodystrophy", "White Matter Disease", "4H Syndrome", "Adrenoleukodystrophy", "AMN", "ALD", "ALD (Adrenoleukodystrophy)", "X-linked Adrenoleukodystrophy", "X-ALD", "Adrenomyeloneuropathy", "Aicardi Goutieres Syndrome", "AGS", "Alexander Disease", "Alexanders Leukodystrophy", "AxD", "ADLD", "Canavan Disease", "CTX", "Cerebrotendinous Xanthomatoses", "Krabbe Disease", "GALC Deficiency", "Globoid Leukodystrophy", "TUBB4A-Related Leukodystrophy", "H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum", "HBSL", "HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity", "LBSL", "Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)", "Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation", "ALSP", "CSF1R Gene Mutation", "HCC - Hypomyelination and Congenital Cataract", "MLC1", "Megalencephalic Leukoencephalopathy With Subcortical Cysts 1", "MLD", "Metachromatic Leukodystrophy", "PMD", "Pelizaeus-Merzbacher Disease", "PLP1 Null Syndrome", "PLP1 Gene Duplication | Blood or Tissue | Mutations", "Pelizaeus-Merzbacher-Like Disease, 1", "Peroxisomal Biogenesis Disorder", "Zellweger Syndrome", "Refsum Disease", "Salla Disease", "Sialic Storage Disease", "Sjögren", "Sjogren-Larsson Syndrome", "Van Der Knapp Disease", "Vanishing White Matter Disease", "Charcot-Marie-Tooth", "CMT", "Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency", "Allan-Herndon-Dudley Syndrome", "Cadasil", "Cockayne Syndrome", "Multiple Sulfatase Deficiency", "Gangliosidoses", "GM2 Gangliosidosis", "BPAN", "Labrune Syndrome", "LCC", "Mucopolysaccharidoses", "TBCK-Related Intellectual Disability Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 236, "start_date": "2017-01-06", "completion_date": "2024-10-31", "has_results": true, "last_update_posted_date": "2025-11-10", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02699190" }, { "nct_id": "NCT05676099", "title": "TSC Biosample Repository and Natural History Database", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Tuberous Sclerosis", "Lymphangioleiomyomatosis" ], "interventions": [ { "name": "Phlebotomy", "type": "PROCEDURE" }, { "name": "Buccal (cheek) swab", "type": "PROCEDURE" }, { "name": "Genetic Testing", "type": "GENETIC" }, { "name": "Tissue donation after routine clinical procedure", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "GENETIC", "OTHER" ], "sponsor": "National Tuberous Sclerosis Association", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 5000, "start_date": "2016-01", "completion_date": "2050-12", "has_results": false, "last_update_posted_date": "2026-06-24", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 24, "location_summary": "Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 19 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Loma Linda", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05676099" }, { "nct_id": "NCT01775072", "title": "Genomic Profiling in Cancer Patients", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Solid Tumors", "Hematologic Cancers" ], "interventions": [ { "name": "molecular profiling of tumors", "type": "GENETIC" }, { "name": "Clinical Germline Analysis", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 200, "start_date": "2013-01", "completion_date": "2027-01", "has_results": false, "last_update_posted_date": "2026-09-24", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 18, "location_summary": "Bridgeport, Connecticut • Hartford, Connecticut • Norwalk, Connecticut + 13 more", "locations": [ { "city": "Bridgeport", "state": "Connecticut" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Norwalk", "state": "Connecticut" }, { "city": "Miami", "state": "Florida" }, { "city": "Basking Ridge", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT01775072" }, { "nct_id": "NCT03482141", "title": "Clinical Utility of Prenatal Whole Exome Sequencing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Structural Anomalies", "Cardiac Anomalies", "Central Nervous System Anomalies", "Thorax Anomalies", "Genito-urinary Anomalies", "Gastrointestinal Anomalies", "Skeletal Anomalies", "Multiple Anomalies" ], "interventions": [ { "name": "Whole Exome Sequencing (WES)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "FEMALE", "summary": "18 Years to 64 Years · Female only" }, "enrollment_count": 316, "start_date": "2017-08-01", "completion_date": "2022-05-13", "has_results": true, "last_update_posted_date": "2023-04-14", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03482141" }, { "nct_id": "NCT04424901", "title": "Trial of Open Label Dipyridamole- In Hospitalized Patients With COVID-19", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19 Pneumonia", "Vascular Complications" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Dipyridamole Tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "UConn Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 41, "start_date": "2020-05-03", "completion_date": "2022-04-24", "has_results": true, "last_update_posted_date": "2023-04-21", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 1, "location_summary": "Farmington, Connecticut", "locations": [ { "city": "Farmington", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT04424901" }, { "nct_id": "NCT06976502", "title": "Health eHeart BioBank", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Diseases", "Cardiac Diseases", "Vascular Diseases", "Cardiovascular Diseases" ], "interventions": [ { "name": "Blood Draw", "type": "PROCEDURE" }, { "name": "Tissue Collection", "type": "PROCEDURE" }, { "name": "DNA Collection", "type": "PROCEDURE" }, { "name": "Medical Chart Review", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500000, "start_date": "2025-04-01", "completion_date": "2035-12", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06976502" }, { "nct_id": "NCT03276637", "title": "Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy Adults", "Genetic Predisposition to Disease" ], "interventions": [ { "name": "Whole exome sequencing", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 105, "start_date": "2017-08-23", "completion_date": "2020-01-11", "has_results": true, "last_update_posted_date": "2024-10-02", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 3, "location_summary": "Boston, Massachusetts • Houston, Texas • San Antonio, Texas", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03276637" }, { "nct_id": "NCT01902901", "title": "Clinical Implementation of Carrier Status Using Next Generation Sequencing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Genetic Disorders" ], "interventions": [ { "name": "Whole Genome Sequencing", "type": "GENETIC" }, { "name": "Carrier status testing", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Kaiser Permanente", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "21 Years to 50 Years" }, "enrollment_count": 384, "start_date": "2014-01", "completion_date": "2018-05", "has_results": true, "last_update_posted_date": "2019-04-17", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01902901" }, { "nct_id": "NCT03290469", "title": "NICUSeq: A Trial to Evaluate the Clinical Utility of Human Whole Genome Sequencing (WGS) Compared to Standard of Care in Acute Care Neonates and Infants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Rare Diseases" ], "interventions": [ { "name": "clinical whole genome sequencing (cWGS)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Illumina, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "120 Days", "sex": "ALL", "summary": "1 Day to 120 Days" }, "enrollment_count": 355, "start_date": "2017-09-14", "completion_date": "2020-01-13", "has_results": false, "last_update_posted_date": "2020-11-18", "last_synced_at": "2026-10-04T13:36:53.129Z", "location_count": 5, "location_summary": "Orange, California • St Louis, Missouri • Omaha, Nebraska + 2 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Omaha", "state": "Nebraska" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03290469" } ] }