{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=clozapine", "query": { "intervention": "clozapine" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 63, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=clozapine&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T05:41:41.129Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00289861", "title": "Risperidone Augmentation in Patients With Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia" ], "interventions": [ { "name": "Risperidone", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 24, "start_date": "2003-02", "completion_date": "2007-03", "has_results": false, "last_update_posted_date": "2013-10-31", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00289861" }, { "nct_id": "NCT04325386", "title": "Clozapine CHAMPION-ECHO Educational Study to Improve Clozapine Use.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Schizophrenia Schizoaffective" ], "interventions": [ { "name": "ECHO Intervention", "type": "OTHER" }, { "name": "eTAU", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Maryland, Baltimore", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "22 Years to 85 Years" }, "enrollment_count": 266, "start_date": "2020-02-01", "completion_date": "2024-09-20", "has_results": true, "last_update_posted_date": "2025-08-12", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 1, "location_summary": "Catonsville, Maryland", "locations": [ { "city": "Catonsville", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04325386" }, { "nct_id": "NCT00169039", "title": "Clozapine Versus Chlorpromazine for Treatment-Unresponsive Schizophrenia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia" ], "interventions": [ { "name": "Clozapine", "type": "DRUG" }, { "name": "Chlorpromazine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Harvard Medical School (HMS and HSDM)", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "19 Years to 60 Years" }, "enrollment_count": 66, "start_date": "1994-12", "completion_date": "2002-02", "has_results": false, "last_update_posted_date": "2015-04-07", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 1, "location_summary": "Jamaica Plain, Massachusetts", "locations": [ { "city": "Jamaica Plain", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00169039" }, { "nct_id": "NCT00156637", "title": "A Study of Strategies to Improve Schizophrenia Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder" ], "interventions": [ { "name": "Team-Based Quality Improvement Intervention", "type": "BEHAVIORAL" }, { "name": "Opinion Leader Intervention", "type": "BEHAVIORAL" }, { "name": "Team Based Quality Improvement", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "US Department of Veterans Affairs", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 106, "start_date": "2005-06", "completion_date": "2008-03", "has_results": false, "last_update_posted_date": "2015-04-07", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 4, "location_summary": "Fayetteville, Arkansas • No. Little Rock, Arkansas • Dayton, Ohio + 1 more", "locations": [ { "city": "Fayetteville", "state": "Arkansas" }, { "city": "No. Little Rock", "state": "Arkansas" }, { "city": "Dayton", "state": "Ohio" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00156637" }, { "nct_id": "NCT02600741", "title": "Family Intervention in Recent Onset Schizophrenia Treatment (FIRST)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Schizophrenia" ], "interventions": [ { "name": "Caregiver psycho-education and skills training", "type": "OTHER" }, { "name": "Caregiver support available at the study site", "type": "OTHER" }, { "name": "Paliperidone palmitate", "type": "DRUG" }, { "name": "Chlorpromazine", "type": "DRUG" }, { "name": "Droperidol", "type": "DRUG" }, { "name": "Fluphenazine", "type": "DRUG" }, { "name": "Haloperidol", "type": "DRUG" }, { "name": "Loxapine", "type": "DRUG" }, { "name": "Perphenazine", "type": "DRUG" }, { "name": "Pimozide", "type": "DRUG" }, { "name": "Prochlorperazine", "type": "DRUG" }, { "name": "Thiothixene", "type": "DRUG" }, { "name": "Thioridazine", "type": "DRUG" }, { "name": "Trifluoperazine", "type": "DRUG" }, { "name": "Aripiprazole", "type": "DRUG" }, { "name": "Asenapine", "type": "DRUG" }, { "name": "Clozapine", "type": "DRUG" }, { "name": "Iloperidone", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Paliperidone", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Risperidone", "type": "DRUG" }, { "name": "Ziprasidone", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Janssen Scientific Affairs, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 296, "start_date": "2015-07-24", "completion_date": "2018-07-05", "has_results": false, "last_update_posted_date": "2019-01-23", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 34, "location_summary": "Bullhead City, Arizona • Oceanside, California • Denver, Colorado + 31 more", "locations": [ { "city": "Bullhead City", "state": "Arizona" }, { "city": "Oceanside", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Lauderdale Lakes", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02600741" }, { "nct_id": "NCT01639872", "title": "Clozapine for Cannabis Use in Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Schizophrenia", "Cannabis Abuse", "Cannabis Dependence", "Dual Diagnosis" ], "interventions": [ { "name": "Clozapine", "type": "DRUG" }, { "name": "Risperidone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dartmouth-Hitchcock Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 49, "start_date": "2013-05-01", "completion_date": "2017-03-29", "has_results": true, "last_update_posted_date": "2020-05-05", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 9, "location_summary": "Garden Grove, California • Oakland, California • Miami, Florida + 6 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Worcester", "state": "Massachusetts" }, { "city": "Grand Rapids", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01639872" }, { "nct_id": "NCT00029458", "title": "Clozapine for Treatment-Resistant Mania", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Clozapine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 42, "start_date": "2002-01", "completion_date": "2005-10", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00029458" }, { "nct_id": "NCT00177164", "title": "Risperdal Consta for Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar I Disorder" ], "interventions": [ { "name": "Injectable Risperidone (Consta) or oral antipsychotic", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 50, "start_date": "2003-11", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2016-04-19", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 4, "location_summary": "Bridgeville, Pennsylvania • DuBois, Pennsylvania • McKeesport, Pennsylvania + 1 more", "locations": [ { "city": "Bridgeville", "state": "Pennsylvania" }, { "city": "DuBois", "state": "Pennsylvania" }, { "city": "McKeesport", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00177164" }, { "nct_id": "NCT00042224", "title": "Electroconvulsive Therapy in Clozapine Refractory Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Schizophrenia" ], "interventions": [ { "name": "Electroconvulsive Therapy (ECT)", "type": "PROCEDURE" }, { "name": "Clozapine", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 39, "start_date": "2000-12", "completion_date": "2008-07", "has_results": true, "last_update_posted_date": "2017-05-15", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 1, "location_summary": "Glen Oaks, New York", "locations": [ { "city": "Glen Oaks", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00042224" }, { "nct_id": "NCT02893371", "title": "Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Lithium Carbonate", "type": "DRUG" }, { "name": "Lamotrigine", "type": "DRUG" }, { "name": "Valproic Acid", "type": "DRUG" }, { "name": "Oxcarbazepine", "type": "DRUG" }, { "name": "Carbamazepine", "type": "DRUG" }, { "name": "Ziprasidone", "type": "DRUG" }, { "name": "Risperidone", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Aripiprazole", "type": "DRUG" }, { "name": "Fluoxetine / Olanzapine", "type": "DRUG" }, { "name": "Haloperidol", "type": "DRUG" }, { "name": "Perphenazine", "type": "DRUG" }, { "name": "Clozapine", "type": "DRUG" }, { "name": "Asenapine", "type": "DRUG" }, { "name": "Lurasidone", "type": "DRUG" }, { "name": "Paliperidone", "type": "DRUG" }, { "name": "Mirtazapine", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Desvenlafaxine", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" }, { "name": "Fluoxetine", "type": "DRUG" }, { "name": "Fluvoxamine", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Vilazodone", "type": "DRUG" }, { "name": "Doxepin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of New Mexico", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1037352, "start_date": "2016-09", "completion_date": "2019-06-30", "has_results": false, "last_update_posted_date": "2024-03-12", "last_synced_at": "2026-09-02T05:41:41.129Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT02893371" } ] }