{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=codeine%2FAPAP&page=6", "query": { "intervention": "codeine/APAP", "page": 6 }, "page_size": 10 }, "pagination": { "page": 6, "page_size": 10, "total_count": 127, "total_pages": 13, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=codeine%2FAPAP&page=7&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=codeine%2FAPAP&page=5&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-26T23:13:18.908Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04642404", "title": "CBD for Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Odontalgia", "Toothache" ], "interventions": [ { "name": "Epidiolex 100 mg/mL Oral Solution", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 64, "start_date": "2021-03-01", "completion_date": "2023-03-13", "has_results": true, "last_update_posted_date": "2024-05-09", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04642404" }, { "nct_id": "NCT07348627", "title": "Opioid-Sparing Joint Replacement", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain Management", "Opioid Consumption" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Oxycodone 5 mg", "type": "DRUG" }, { "name": "Multimodal Non-Opioid Analgesia", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2026-03-19", "completion_date": "2028-08", "has_results": false, "last_update_posted_date": "2026-04-17", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07348627" }, { "nct_id": "NCT06484439", "title": "Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Pain, Post-operative", "Third Molar", "Oral Surgery", "Pain, Acute" ], "interventions": [ { "name": "Ketorolac", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Hydrocodone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "United States Naval Medical Center, San Diego", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "44 Years", "sex": "ALL", "summary": "18 Years to 44 Years" }, "enrollment_count": 80, "start_date": "2018-02-14", "completion_date": "2021-12-01", "has_results": false, "last_update_posted_date": "2024-07-10", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06484439" }, { "nct_id": "NCT02858310", "title": "E7 TCR T Cells for Human Papillomavirus-Associated Cancers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Papillomavirus Infections", "Cervical Intraepithelial Neoplasia", "Carcinoma In Situ", "Vulvar Neoplasms", "Vulvar Diseases" ], "interventions": [ { "name": "E7 TCR cells", "type": "BIOLOGICAL" }, { "name": "Aldesleukin", "type": "DRUG" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "EKG", "type": "DIAGNOSTIC_TEST" }, { "name": "Biopsy", "type": "PROCEDURE" }, { "name": "Chest CT and MRI or PET", "type": "DIAGNOSTIC_TEST" }, { "name": "PFT", "type": "DIAGNOSTIC_TEST" }, { "name": "Granisetron", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Droperidol", "type": "DRUG" }, { "name": "Prochlorperazine", "type": "DRUG" }, { "name": "Diphenoxylate HCL", "type": "DRUG" }, { "name": "Atropine sulfate", "type": "DRUG" }, { "name": "Codeine sulfate", "type": "DRUG" }, { "name": "Loperamide", "type": "DRUG" }, { "name": "Indomethacin", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Diphenhydramine HCL", "type": "DRUG" }, { "name": "Hydroxyzine HCL", "type": "DRUG" }, { "name": "Meperidine", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "DIAGNOSTIC_TEST", "PROCEDURE" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 224, "start_date": "2017-01-27", "completion_date": "2025-07-02", "has_results": true, "last_update_posted_date": "2026-03-09", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 2, "location_summary": "Bethesda, Maryland • New Brunswick, New Jersey", "locations": [ { "city": "Bethesda", "state": "Maryland" }, { "city": "New Brunswick", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT02858310" }, { "nct_id": "NCT06973785", "title": "Non-Narcotic Pain Control After ACL Reconstruction", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "ACL - Anterior Cruciate Ligament Rupture", "ACL Injuries" ], "interventions": [ { "name": "dispense of study drug", "type": "DRUG" }, { "name": "Ketorolac", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "15 Years to 55 Years" }, "enrollment_count": 30, "start_date": "2025-07-15", "completion_date": "2027-06-15", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 3, "location_summary": "Coral Springs, Florida • Garfield, Ohio • Strongsville, Ohio", "locations": [ { "city": "Coral Springs", "state": "Florida" }, { "city": "Garfield", "state": "Ohio" }, { "city": "Strongsville", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06973785" }, { "nct_id": "NCT05974501", "title": "Pre vs Post Block in Total Knee Arthroplasty (TKA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Knee Osteoarthritis", "Arthroplasty Complications", "Postoperative Pain" ], "interventions": [ { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Lyrica", "type": "DRUG" }, { "name": "Celebrex", "type": "DRUG" }, { "name": "Meloxicam", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 84, "start_date": "2023-09-29", "completion_date": "2024-01-22", "has_results": true, "last_update_posted_date": "2025-02-12", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05974501" }, { "nct_id": "NCT02601027", "title": "Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast - Female" ], "interventions": [ { "name": "Transversus Abdominis Plane (TAP) block", "type": "PROCEDURE" }, { "name": "Nimbus Infusion Pump IV Administration", "type": "DEVICE" }, { "name": "Bupivacaine infusion", "type": "DRUG" }, { "name": "Acetominophen", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 120, "start_date": "2015-11", "completion_date": "2021-06", "has_results": true, "last_update_posted_date": "2021-09-23", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02601027" }, { "nct_id": "NCT03137030", "title": "A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Opioid-Related Disorders", "Pain, Acute", "Pain, Postoperative" ], "interventions": [ { "name": "GRT7014 - Abuse Deterrend Tablet", "type": "DRUG" }, { "name": "Norco 5Mg-325Mg Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Grünenthal GmbH", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 0, "start_date": "2017-09", "completion_date": "2018-01", "has_results": false, "last_update_posted_date": "2017-07-21", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "Lenexa, Kansas", "locations": [ { "city": "Lenexa", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03137030" }, { "nct_id": "NCT04423107", "title": "Assessment of Postop Hypospadias Pain", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypospadias" ], "interventions": [ { "name": "Acetaminophen, Ibuprofen", "type": "DRUG" }, { "name": "Acetaminophen, Ibuprofen, Oxycodone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "23 Months", "sex": "MALE", "summary": "6 Months to 23 Months · Male only" }, "enrollment_count": 150, "start_date": "2020-07-01", "completion_date": "2023-01", "has_results": false, "last_update_posted_date": "2020-07-31", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "Oklahoma City, Oklahoma", "locations": [ { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT04423107" }, { "nct_id": "NCT00685295", "title": "Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Pain, Fracture, Sprain" ], "interventions": [ { "name": "Fentanyl", "type": "DRUG" }, { "name": "Lansoprazole", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 60, "start_date": "2008-08", "completion_date": "2009-02", "has_results": true, "last_update_posted_date": "2017-02-09", "last_synced_at": "2026-10-26T23:13:18.908Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00685295" } ] }