{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=combined+therapy+treatment&page=19", "query": { "intervention": "combined therapy treatment", "page": 19 }, "page_size": 10 }, "pagination": { "page": 19, "page_size": 10, "total_count": 12515, "total_pages": 1252, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=combined+therapy+treatment&page=20&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=combined+therapy+treatment&page=18&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-14T02:57:28.330Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00516958", "title": "Pilot Study of the Safety and Clinical Efficacy of Topical Dermacyn™ Wound Care to Treat Mild Diabetic Foot Infections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Foot Ulcer, Diabetic" ], "interventions": [ { "name": "Topical Dermacyn", "type": "DRUG" }, { "name": "Topical Dermacyn and Levofloxacin", "type": "DRUG" }, { "name": "Topical Saline and Levofloxacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Oculus Innovative Sciences, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 65, "start_date": "2007-05", "completion_date": "2007-12", "has_results": false, "last_update_posted_date": "2008-01-14", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 16, "location_summary": "Tucson, Arizona • La Jolla, California • Los Angeles, California + 13 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Santa Rosa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00516958" }, { "nct_id": "NCT04501978", "title": "ACTIV-3: Therapeutics for Inpatients With COVID-19", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Covid19" ], "interventions": [ { "name": "LY3819253", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Remdesivir", "type": "BIOLOGICAL" }, { "name": "VIR-7831", "type": "BIOLOGICAL" }, { "name": "BRII-196/BRII-198", "type": "BIOLOGICAL" }, { "name": "AZD7442", "type": "BIOLOGICAL" }, { "name": "MP0420", "type": "DRUG" }, { "name": "PF-07304814", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2753, "start_date": "2020-08-04", "completion_date": "2023-07-14", "has_results": false, "last_update_posted_date": "2023-08-25", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 98, "location_summary": "Tucson, Arizona • Chula Vista, California • Fresno, California + 64 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Chula Vista", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "La Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04501978" }, { "nct_id": "NCT07261085", "title": "A Study to Learn How Paxlovid [Nirmatrelvir-ritonavir/PF-07321332] Works in COVID-19 Patients Who Are Elderly or Have Medical Conditions.", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "COVID-19" ], "interventions": [ { "name": "nirmatrelvir-ritonavir", "type": "DRUG" }, { "name": "No treatment", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 99000, "start_date": "2025-10-27", "completion_date": "2026-02-26", "has_results": false, "last_update_posted_date": "2026-06-29", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07261085" }, { "nct_id": "NCT00002215", "title": "A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Emivirine", "type": "DRUG" }, { "name": "Nelfinavir mesylate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Triangle Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": null, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002215" }, { "nct_id": "NCT03960125", "title": "Photodynamic Therapy and Microvesicles", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Photodynamic Therapy", "Microvesicle Particle" ], "interventions": [ { "name": "Photodynamic Therapy", "type": "DEVICE" }, { "name": "4% Imipramine", "type": "DRUG" }, { "name": "Base Cream", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Wright State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "21 Years to 45 Years" }, "enrollment_count": 0, "start_date": "2021-03-29", "completion_date": "2022-09", "has_results": false, "last_update_posted_date": "2022-09-13", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 1, "location_summary": "Fairborn, Ohio", "locations": [ { "city": "Fairborn", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03960125" }, { "nct_id": "NCT00000640", "title": "A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pneumonia, Pneumocystis Carinii", "HIV Infections" ], "interventions": [ { "name": "Primaquine", "type": "DRUG" }, { "name": "Sulfamethoxazole-Trimethoprim", "type": "DRUG" }, { "name": "Dapsone", "type": "DRUG" }, { "name": "Clindamycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 290, "start_date": null, "completion_date": "1994-09", "has_results": false, "last_update_posted_date": "2021-11-03", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 32, "location_summary": "Los Angeles, California • Palo Alto, California • San Francisco, California + 23 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Jose", "state": "California" }, { "city": "San Mateo", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000640" }, { "nct_id": "NCT00645710", "title": "Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Liver Metastases", "Recurrent Colon Cancer", "Recurrent Rectal Cancer", "Stage IV Colon Cancer", "Stage IV Rectal Cancer" ], "interventions": [ { "name": "gemcitabine hydrochloride", "type": "DRUG" }, { "name": "floxuridine", "type": "DRUG" }, { "name": "proteomic profiling", "type": "GENETIC" }, { "name": "matrix-assisted laser desorption/ionization time of flight mass spectrometry", "type": "OTHER" }, { "name": "liquid chromatography", "type": "OTHER" }, { "name": "yttrium Y 90 anti-CEA monoclonal antibody cT84.66", "type": "RADIATION" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "mass spectrometry", "type": "OTHER" }, { "name": "pharmacological study", "type": "OTHER" } ], "intervention_types": [ "DRUG", "GENETIC", "OTHER", "RADIATION" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 16, "start_date": "2005-02-11", "completion_date": "2018-02-07", "has_results": true, "last_update_posted_date": "2019-03-28", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00645710" }, { "nct_id": "NCT05790213", "title": "Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "Androgen Deprivation Therapy (ADT)", "type": "DRUG" }, { "name": "Focal prostate ablation (focal therapy)", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 57, "start_date": "2025-05-05", "completion_date": "2028-12-18", "has_results": false, "last_update_posted_date": "2026-06-16", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05790213" }, { "nct_id": "NCT00147758", "title": "WelChol® and Sulfonylurea in Treating Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Colesevelam hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 400, "start_date": "2004-06", "completion_date": "2006-08", "has_results": false, "last_update_posted_date": "2012-01-18", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 45, "location_summary": "Birmingham, Alabama • Tuscumbia, Alabama • Little Rock, Arkansas + 42 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tuscumbia", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Searcy", "state": "Arkansas" }, { "city": "Concord", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00147758" }, { "nct_id": "NCT05036226", "title": "COAST Therapy in Advanced Solid Tumors and Prostate Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Prostate Cancer Recurrent", "Solid Tumor, Adult" ], "interventions": [ { "name": "Hydroxychloroquine, Metformin, Sirolimus", "type": "COMBINATION_PRODUCT" }, { "name": "Hydroxychloroquine, Metformin, Sirolimus, Dasatanib", "type": "COMBINATION_PRODUCT" }, { "name": "Hydroxychloroquine, Metformin, Sirolimus, Nelfinavir", "type": "COMBINATION_PRODUCT" }, { "name": "Hydroxychloroquine, Metformin, Sirolimus, Nelfinavir, Dasatinib", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 76, "start_date": "2022-03-03", "completion_date": "2028-05-21", "has_results": false, "last_update_posted_date": "2026-05-13", "last_synced_at": "2026-10-14T02:57:28.330Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05036226" } ] }