{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cooling+device&page=2",
    "query": {
      "intervention": "cooling device",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=cooling+device&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T07:06:07.305Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03289364",
      "title": "Penguin Cold Caps in the Prevention of Hair Loss in Breast Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Penguin Cold Caps",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Providence Health & Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2017-08-24",
      "completion_date": "2021-08-19",
      "has_results": true,
      "last_update_posted_date": "2026-04-28",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03289364"
    },
    {
      "nct_id": "NCT07422376",
      "title": "Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alopecia"
      ],
      "interventions": [
        {
          "name": "Paxman Scalp Cooling System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Charles Mays",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-03-01",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Kingsport, Tennessee",
      "locations": [
        {
          "city": "Kingsport",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07422376"
    },
    {
      "nct_id": "NCT00670124",
      "title": "Hypothermia to Prevent High Intracranial Pressure in Patients With Acute Liver Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Liver Failure",
        "Intracranial Hypertension"
      ],
      "interventions": [
        {
          "name": "Hypothermia by the use of Blanketrol II, Cincinnati Sub-Zero",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rigshospitalet, Denmark",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2005-01",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2014-11-05",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00670124"
    },
    {
      "nct_id": "NCT04936061",
      "title": "Transnasal Cooling for Migraine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine",
        "Episodic Migraine",
        "Migraine With Aura",
        "Migraine Without Aura"
      ],
      "interventions": [
        {
          "name": "CoolStat active device",
          "type": "DEVICE"
        },
        {
          "name": "CoolStat sham device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CoolTech LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 24,
      "start_date": "2021-10-14",
      "completion_date": "2022-09-30",
      "has_results": true,
      "last_update_posted_date": "2023-09-29",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 3,
      "location_summary": "Scottsdale, Arizona • East Lansing, Michigan • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04936061"
    },
    {
      "nct_id": "NCT06874361",
      "title": "Cooling to Alleviate Migraine #3",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine With or Without Aura",
        "Migraine",
        "Migraine Headache"
      ],
      "interventions": [
        {
          "name": "Mi-Helper",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mi-Helper, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 156,
      "start_date": "2025-03-24",
      "completion_date": "2025-12-15",
      "has_results": true,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Indian Harbour Beach, Florida",
      "locations": [
        {
          "city": "Indian Harbour Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06874361"
    },
    {
      "nct_id": "NCT06729632",
      "title": "Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Noise Exposure",
        "Noise-induced Hearing Loss",
        "Noise; Adverse Effect",
        "Mild Therapeutic Hypothermia",
        "Cooling",
        "Occupational Exposure",
        "Occupational Health",
        "Hidden Hearing Loss"
      ],
      "interventions": [
        {
          "name": "Cold pack-delivered mild therapeutic hypothermia",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Restorear Devices LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 116,
      "start_date": "2024-12-19",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06729632"
    },
    {
      "nct_id": "NCT06585709",
      "title": "OUD (Opioid Use Disorder) Target Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Active repetitive Transcranial Magnetic Stimulation (rTMS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham repetitive Transcranial Magnetic Stimulation (rTMS)",
          "type": "DEVICE"
        },
        {
          "name": "High Ventral Striatal Reactivity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Low Ventral Striatal Reactivity",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2024-12-31",
      "completion_date": "2026-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06585709"
    },
    {
      "nct_id": "NCT04839861",
      "title": "Examining the Impacts of Parent-Child Interactive Activities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emotional Regulation"
      ],
      "interventions": [
        {
          "name": "Mightier Family Games",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mightier online gameplay",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Neuromotion Labs",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 42,
      "start_date": "2021-05-07",
      "completion_date": "2021-10-13",
      "has_results": false,
      "last_update_posted_date": "2021-10-20",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04839861"
    },
    {
      "nct_id": "NCT06983041",
      "title": "Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vulvovaginal Candidiasis (VVC)",
        "Yeast Vaginitis"
      ],
      "interventions": [
        {
          "name": "vaginal cooling device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Coologics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "49 Years",
        "sex": "FEMALE",
        "summary": "22 Years to 49 Years · Female only"
      },
      "enrollment_count": 55,
      "start_date": "2025-05-22",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 10,
      "location_summary": "Jacksonville, Florida • Miami, Florida • Smyrna, Georgia + 7 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Smyrna",
          "state": "Georgia"
        },
        {
          "city": "Snellville",
          "state": "Georgia"
        },
        {
          "city": "Idaho Falls",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06983041"
    },
    {
      "nct_id": "NCT05849181",
      "title": "Localized Body Cooling Technology on Sleep and Metabolism in African, American With Overweight and Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight or Obesity"
      ],
      "interventions": [
        {
          "name": "Moona Device",
          "type": "DEVICE"
        },
        {
          "name": "Inactive Moona Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 18,
      "start_date": "2024-03-25",
      "completion_date": "2025-08-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-09-11T07:06:07.305Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05849181"
    }
  ]
}