{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=creatine+supplementation",
    "query": {
      "intervention": "creatine supplementation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 114,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=creatine+supplementation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T20:18:44.015Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00851006",
      "title": "Creatine Treatment for Female Adolescents With Depression Who Are Non-Responders to Fluoxetine or Escitalopram",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Creatine Monohydrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "FEMALE",
        "summary": "13 Years to 18 Years · Female only"
      },
      "enrollment_count": 13,
      "start_date": "2009-04",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-12",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00851006"
    },
    {
      "nct_id": "NCT01381354",
      "title": "Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Progressive exercise",
          "type": "OTHER"
        },
        {
          "name": "Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV",
          "type": "DEVICE"
        },
        {
          "name": "Modified paleolithic diet",
          "type": "OTHER"
        },
        {
          "name": "Omega 3 fatty acids",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Full Spectrum vitamin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Essential - hydroxytyrosol",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Maltodextrin fiber supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Mineral boost (magnesium)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Niacinamide",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Methyl B12",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Taurine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "creatine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "thiamine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "riboflavin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "N acetylcysteine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "alpha lipoic acid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "L acetyl carnitine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "methyl folate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "coenzyme Q",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "self massage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "learning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Coconut oil",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE",
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 38,
      "start_date": "2010-10",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2018-06-26",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01381354"
    },
    {
      "nct_id": "NCT06967428",
      "title": "Effect of Metabolic Modulation on a Post-acute COVID-19 Vaccination Syndrome (PACVS) Cohort",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vaccine Adverse Reaction",
        "Post Acute Covid-19 Vaccination Syndrome"
      ],
      "interventions": [
        {
          "name": "Combined metabolic modulator",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Rice Protein Powder with Vitamin C",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Independent Medical Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-09-01",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06967428"
    },
    {
      "nct_id": "NCT02661334",
      "title": "Measuring Uniformed Servicemembers' Fitness Scores on Creatine Loading and Exercise",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Fitness"
      ],
      "interventions": [
        {
          "name": "Creatine Monohydrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Rice Flour",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "David Grant U.S. Air Force Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 6,
      "start_date": "2015-08-01",
      "completion_date": "2018-02-13",
      "has_results": false,
      "last_update_posted_date": "2020-04-03",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Fairfield, California",
      "locations": [
        {
          "city": "Fairfield",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02661334"
    },
    {
      "nct_id": "NCT00005674",
      "title": "Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS]",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Creatine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Center for Research Resources (NCRR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005674"
    },
    {
      "nct_id": "NCT00352196",
      "title": "Janssen Asperger's MRS (Magnetic Resonance Spectroscopy Risperidone Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Asperger's Disorder"
      ],
      "interventions": [
        {
          "name": "Risperidone",
          "type": "DRUG"
        },
        {
          "name": "Magnetic Resonance Spectroscopy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2001-11",
      "completion_date": "2007-05",
      "has_results": false,
      "last_update_posted_date": "2015-01-14",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00352196"
    },
    {
      "nct_id": "NCT00531843",
      "title": "The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Venous Thromboembolism"
      ],
      "interventions": [
        {
          "name": "fondaparinux sodium",
          "type": "DRUG"
        },
        {
          "name": "sequential compression devices",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mary Knudson, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 105,
      "start_date": "2007-12",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2013-12-24",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00531843"
    },
    {
      "nct_id": "NCT00005766",
      "title": "Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Creatinine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Center for Research Resources (NCRR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005766"
    },
    {
      "nct_id": "NCT00016653",
      "title": "Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Muscular Dystrophy, Duchenne"
      ],
      "interventions": [
        {
          "name": "Creatine Monohydrate",
          "type": "DRUG"
        },
        {
          "name": "Glutamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cooperative International Neuromuscular Research Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "9 Years",
        "sex": "MALE",
        "summary": "5 Years to 9 Years · Male only"
      },
      "enrollment_count": 48,
      "start_date": "2000-06",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2011-10-27",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00016653"
    },
    {
      "nct_id": "NCT06018480",
      "title": "The Effect of NADPH Oxidase and Creatine Supplementation on Microvascular Blood Flow Regulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Creatine Monohydrate",
          "type": "OTHER"
        },
        {
          "name": "Maltodextrin (Placebo)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 9,
      "start_date": "2023-08-29",
      "completion_date": "2024-01-30",
      "has_results": false,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-09-03T20:18:44.015Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06018480"
    }
  ]
}