{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=dental+floss",
    "query": {
      "intervention": "dental floss"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=dental+floss&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T09:22:54.496Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05600231",
      "title": "A Study of Virtually Supervised Mouth Rinses and Flossing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "LISTERINE COOL MINT Antiseptic Mouthwash",
          "type": "OTHER"
        },
        {
          "name": "LISTERINE COOL MINT ZERO Alcohol Mouthwash",
          "type": "OTHER"
        },
        {
          "name": "Reach Unflavored Waxed Dental Floss",
          "type": "OTHER"
        },
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 284,
      "start_date": "2022-04-18",
      "completion_date": "2022-07-25",
      "has_results": false,
      "last_update_posted_date": "2023-06-18",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05600231"
    },
    {
      "nct_id": "NCT01549587",
      "title": "Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "0.243% sodium fluoride",
          "type": "DRUG"
        },
        {
          "name": "toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "dental floss",
          "type": "DEVICE"
        },
        {
          "name": "0.454% stannous fluoride",
          "type": "DRUG"
        },
        {
          "name": "0.07% Cetylpyridinium chloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 746,
      "start_date": "2012-02",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2023-04-21",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01549587"
    },
    {
      "nct_id": "NCT06515483",
      "title": "Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Supragingival Plaque"
      ],
      "interventions": [
        {
          "name": "Brushing and Flossing of teeth",
          "type": "DEVICE"
        },
        {
          "name": "Brushing Only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 64,
      "start_date": "2024-10-15",
      "completion_date": "2024-12-04",
      "has_results": true,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06515483"
    },
    {
      "nct_id": "NCT01559987",
      "title": "Dental Plaque Removal Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Gum Disease"
      ],
      "interventions": [
        {
          "name": "Manual Toothbrush only",
          "type": "OTHER"
        },
        {
          "name": "MTB + Waterpik Ultra Water Flosser 'High'",
          "type": "OTHER"
        },
        {
          "name": "MTB + Floss (MTB+Floss)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 270,
      "start_date": "2012-02",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01559987"
    },
    {
      "nct_id": "NCT03876353",
      "title": "University of New Mexico Dental Hygiene",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oral Plaque Biofilm"
      ],
      "interventions": [
        {
          "name": "Floss",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2019-01-07",
      "completion_date": "2019-02-11",
      "has_results": false,
      "last_update_posted_date": "2019-03-15",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03876353"
    },
    {
      "nct_id": "NCT04954313",
      "title": "Baseline Oral Health Study: UnCoVer the Connections to General Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Diabetes Type 2"
      ],
      "interventions": [
        {
          "name": "Subgingival chlorhexidine irrigation",
          "type": "DRUG"
        },
        {
          "name": "Dental Supplies",
          "type": "OTHER"
        },
        {
          "name": "Periodonal Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 786,
      "start_date": "2021-09-28",
      "completion_date": "2025-02-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Kannapolis, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Kannapolis",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04954313"
    },
    {
      "nct_id": "NCT03237624",
      "title": "Functional Chewing Gum in Reduction of Gingival Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Functional Chitosan Chewing Gum",
          "type": "DEVICE"
        },
        {
          "name": "Control Chewing Gum",
          "type": "DEVICE"
        },
        {
          "name": "Oral hygiene measures",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2018-01-31",
      "completion_date": "2020-01-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-26",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03237624"
    },
    {
      "nct_id": "NCT01128374",
      "title": "The Effect of Non-Surgical Periodontal Therapy on Glycemic Control and Bacterial Levels in a Mexican-American Population With Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes Mellitus",
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Periodontal Scaling and root planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 134,
      "start_date": "2010-06",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-01-15",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128374"
    },
    {
      "nct_id": "NCT02906982",
      "title": "Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Discoloration",
        "Periodontal Diseases"
      ],
      "interventions": [
        {
          "name": "Gum health formulation in intra-oral device",
          "type": "OTHER"
        },
        {
          "name": "Gum health formulation on toothbrush",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Glo Science, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2015-10",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-09-20",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02906982"
    },
    {
      "nct_id": "NCT00855933",
      "title": "A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Experimental Floss",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2009-01",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2013-02-08",
      "last_synced_at": "2026-09-07T09:22:54.496Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00855933"
    }
  ]
}