{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=diffusion+tensor+imaging", "query": { "intervention": "diffusion tensor imaging" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 100, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=diffusion+tensor+imaging&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T11:03:51.403Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03811405", "title": "Physiology, Imaging and Modeling of Essential Tremor", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Essential Tremor", "Parkinson Disease", "Dystonia" ], "interventions": [ { "name": "Active biphasic pulse stimulation---Home Settings", "type": "DEVICE" }, { "name": "Active biphasic pulse stimulation---VIN Biphasic", "type": "DEVICE" }, { "name": "Active biphasic pulse stimulation---Stimulator Off", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 12, "start_date": "2021-04-01", "completion_date": "2025-06-01", "has_results": false, "last_update_posted_date": "2025-06-26", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 2, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03811405" }, { "nct_id": "NCT03808675", "title": "Aerobic Exercise in Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "Aerobic walking", "type": "BEHAVIORAL" }, { "name": "Usual care with PD specific health education", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 57, "start_date": "2019-07-01", "completion_date": "2024-09-30", "has_results": true, "last_update_posted_date": "2026-03-12", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 2, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" }, { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT03808675" }, { "nct_id": "NCT02359565", "title": "Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Constitutional Mismatch Repair Deficiency Syndrome", "Lynch Syndrome", "Malignant Glioma", "Recurrent Brain Neoplasm", "Recurrent Childhood Ependymoma", "Recurrent Diffuse Intrinsic Pontine Glioma", "Recurrent Medulloblastoma", "Refractory Brain Neoplasm", "Refractory Diffuse Intrinsic Pontine Glioma", "Refractory Ependymoma", "Refractory Medulloblastoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Conventional Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Diffusion Tensor Imaging", "type": "PROCEDURE" }, { "name": "Diffusion Weighted Imaging", "type": "PROCEDURE" }, { "name": "Dynamic Contrast-enhanced MR Perfusion", "type": "PROCEDURE" }, { "name": "Dynamic Susceptibility Contrast-Perfusion-Weighted Imaging", "type": "PROCEDURE" }, { "name": "Magnetic Resonance Spectroscopic Imaging", "type": "PROCEDURE" }, { "name": "Pembrolizumab", "type": "BIOLOGICAL" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "30 Years", "sex": "ALL", "summary": "1 Year to 30 Years" }, "enrollment_count": 71, "start_date": "2015-06-03", "completion_date": "2027-01-16", "has_results": false, "last_update_posted_date": "2026-07-20", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 11, "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02359565" }, { "nct_id": "NCT02076152", "title": "FMISO PET Study of Glioblastoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Recurrent Glioblastoma" ], "interventions": [ { "name": "FMISO PET", "type": "DEVICE" }, { "name": "MRI", "type": "DEVICE" }, { "name": "Bevacizumab", "type": "DRUG" }, { "name": "CCNU", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2014-02", "completion_date": "2019-04", "has_results": true, "last_update_posted_date": "2021-07-30", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02076152" }, { "nct_id": "NCT05658731", "title": "Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Brain Tumor", "Head and Neck Cancer" ], "interventions": [ { "name": "substructure informed planning", "type": "RADIATION" }, { "name": "Neurocognitive Testing", "type": "OTHER" }, { "name": "MRI", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "RADIATION", "OTHER", "DIAGNOSTIC_TEST" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "1 Year", "maximum_age": "26 Years", "sex": "ALL", "summary": "1 Year to 26 Years" }, "enrollment_count": 338, "start_date": "2023-05-17", "completion_date": "2035-12", "has_results": false, "last_update_posted_date": "2026-06-29", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 2, "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05658731" }, { "nct_id": "NCT00940615", "title": "The Effect of Aerobic Exercise on Mild Traumatic Brain Injury", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Traumatic Brain Injury" ], "interventions": [ { "name": "aerobic exercise", "type": "OTHER" }, { "name": "stretching/toning", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "US Department of Veterans Affairs", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 24, "start_date": "2009-09", "completion_date": "2010-09", "has_results": false, "last_update_posted_date": "2015-06-26", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00940615" }, { "nct_id": "NCT00730002", "title": "Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Neuropsychiatric Systemic Lupus Erythematosus" ], "interventions": [ { "name": "Magnetic Resonance Angiography (MRA)", "type": "PROCEDURE" }, { "name": "Magnetic resonance imaging", "type": "PROCEDURE" }, { "name": "MRA", "type": "PROCEDURE" }, { "name": "diffusion Imaging", "type": "PROCEDURE" }, { "name": "perfusion imaging.", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 66, "start_date": "2008-03", "completion_date": "2014-12", "has_results": false, "last_update_posted_date": "2015-12-14", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00730002" }, { "nct_id": "NCT02277561", "title": "Voxel Based Diffusion Tensor Imaging in Predicting Response in Patients With Brain Metastases Undergoing Whole Brain Radiation Therapy or Stereotactic Radiosurgery", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tumors Metastatic to Brain", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "diffusion tensor imaging", "type": "PROCEDURE" }, { "name": "whole-brain radiation therapy", "type": "RADIATION" }, { "name": "stereotactic radiosurgery", "type": "RADIATION" }, { "name": "contrast-enhanced magnetic resonance imaging", "type": "PROCEDURE" }, { "name": "diffusion-weighted magnetic resonance imaging", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "RADIATION" ], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 0, "start_date": "2013-04", "completion_date": "2014-12", "has_results": false, "last_update_posted_date": "2020-03-04", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02277561" }, { "nct_id": "NCT04820881", "title": "Cerebrovascular Reactivity and Oxygen Metabolism as Markers of Neurodegeneration After Traumatic Brain Injury", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Neurodegenerative Diseases" ], "interventions": [], "intervention_types": [], "sponsor": "Washington D.C. Veterans Affairs Medical Center", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "50 Years to 80 Years" }, "enrollment_count": 60, "start_date": "2021-10-01", "completion_date": "2024-09", "has_results": false, "last_update_posted_date": "2022-04-27", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 1, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04820881" }, { "nct_id": "NCT03600740", "title": "Advancing Pre-operative Targeting for Deep Brain Stimulation in the Globus Pallidus Internus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Parkinson Disease" ], "interventions": [ { "name": "DBS Programming", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2018-08-17", "completion_date": "2020-05-18", "has_results": true, "last_update_posted_date": "2021-04-29", "last_synced_at": "2026-09-02T11:03:51.403Z", "location_count": 3, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03600740" } ] }