{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=divalproex&page=4", "query": { "intervention": "divalproex", "page": 4 }, "page_size": 10 }, "pagination": { "page": 4, "page_size": 10, "total_count": 215, "total_pages": 22, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=divalproex&page=5&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=divalproex&page=3&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-21T03:27:28.652Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01575561", "title": "This is an Open-label, Multi-center, Extension Study Designed to Evaluate the Longer Term Safety, Tolerability and Effectiveness of Lurasidone, Flexibly Dosed, Adjunctive to Lithium or Divalproex for the Treatment of Subjects With Bipolar I Disorder Who Have Participated in Study D1050296", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar I Disorder" ], "interventions": [ { "name": "Lurasidone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sumitomo Pharma America, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 377, "start_date": "2012-06", "completion_date": "2015-07", "has_results": true, "last_update_posted_date": "2016-08-22", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 25, "location_summary": "Dothan, Alabama • Glendale, California • Los Angeles, California + 22 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Glendale", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01575561" }, { "nct_id": "NCT03235531", "title": "Assessment of Valproate on Ethanol Withdrawal", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alcohol Dependence", "Alcohol Withdrawal Syndrome", "Trauma", "Heavy Drinking", "Alcohol Use Disorder" ], "interventions": [ { "name": "Valproate", "type": "DRUG" }, { "name": "Lorazepam", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "CAMC Health System", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2017-07-11", "completion_date": "2019-06-25", "has_results": false, "last_update_posted_date": "2026-08-18", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 2, "location_summary": "Charleston, West Virginia", "locations": [ { "city": "Charleston", "state": "West Virginia" }, { "city": "Charleston", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03235531" }, { "nct_id": "NCT01233609", "title": "Trial of Oral Valproic Acid for Retinitis Pigmentosa", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Retinitis Pigmentosa" ], "interventions": [ { "name": "Valproic Acid", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Foundation Fighting Blindness", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 90, "start_date": "2010-11", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-12-02", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 6, "location_summary": "Miami, Florida • Ann Arbor, Michigan • Portland, Oregon + 3 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Portland", "state": "Oregon" }, { "city": "Memphis", "state": "Tennessee" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01233609" }, { "nct_id": "NCT00012558", "title": "Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "lithium", "type": "DRUG" }, { "name": "valproate", "type": "DRUG" }, { "name": "bupropion", "type": "DRUG" }, { "name": "paroxetine", "type": "DRUG" }, { "name": "lamotrigine", "type": "DRUG" }, { "name": "risperidone", "type": "DRUG" }, { "name": "inositol", "type": "DRUG" }, { "name": "tranylcypromine", "type": "DRUG" }, { "name": "Cognitive Behavioral Therapy", "type": "BEHAVIORAL" }, { "name": "Family-focused Therapy", "type": "BEHAVIORAL" }, { "name": "Interpersonal and Social Rhythms Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": null, "sex": "ALL", "summary": "15 Years and older" }, "enrollment_count": 5000, "start_date": "1998-09", "completion_date": "2005-09", "has_results": false, "last_update_posted_date": "2007-05-04", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 11, "location_summary": "Stanford, California • Denver, Colorado • Boston, Massachusetts + 8 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Worcester", "state": "Massachusetts" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00012558" }, { "nct_id": "NCT01900730", "title": "Study of Valproic Acid (VPA) vs Placebo to Shorten Time of Indwelling Pleural Catheter", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Valproic Acid (VPA)", "type": "DRUG" }, { "name": "Questionnaires", "type": "BEHAVIORAL" }, { "name": "Pill Diary", "type": "BEHAVIORAL" }, { "name": "Drainage Diary", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2014-07-31", "completion_date": "2018-06-01", "has_results": true, "last_update_posted_date": "2020-02-25", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01900730" }, { "nct_id": "NCT01284517", "title": "Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Depression" ], "interventions": [ { "name": "Lurasidone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sumitomo Pharma America, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 356, "start_date": "2010-11", "completion_date": "2012-08", "has_results": true, "last_update_posted_date": "2013-11-26", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 22, "location_summary": "Costa Mesa, California • Riverside, California • San Diego, California + 16 more", "locations": [ { "city": "Costa Mesa", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Santa Ana", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01284517" }, { "nct_id": "NCT00207935", "title": "Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Epilepsy", "Mental Retardation", "Developmental Disabilities" ], "interventions": [ { "name": "Swallow instruction", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Children's National Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "4 Years to 18 Years" }, "enrollment_count": 20, "start_date": "2005-08", "completion_date": "2007-03", "has_results": false, "last_update_posted_date": "2008-05-05", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 1, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00207935" }, { "nct_id": "NCT00195806", "title": "Study Designed to Evaluate the Safety of Prophylactic Depakote ER in the Treatment of Adolescents With Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Migraine" ], "interventions": [ { "name": "divalproex sodium", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Abbott", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "12 Years to 17 Years" }, "enrollment_count": 315, "start_date": "2005-02", "completion_date": null, "has_results": false, "last_update_posted_date": "2007-09-03", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 1, "location_summary": "North Chicago, Illinois", "locations": [ { "city": "North Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00195806" }, { "nct_id": "NCT00794625", "title": "Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study)", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Attention Deficit Disorder With Hyperactivity" ], "interventions": [ { "name": "Valproate", "type": "DRUG" }, { "name": "Risperidone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Stimulant medication", "type": "DRUG" }, { "name": "Behavioral family counseling", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Joseph Blader", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 270, "start_date": "2008-11", "completion_date": "2013-04", "has_results": false, "last_update_posted_date": "2012-07-16", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 3, "location_summary": "Glen Oaks, New York • Stony Brook, New York • San Antonio, Texas", "locations": [ { "city": "Glen Oaks", "state": "New York" }, { "city": "Stony Brook", "state": "New York" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00794625" }, { "nct_id": "NCT00206778", "title": "Six Month Trial of Lamotrigine vs. Sodium Valproate for Treatment of Mixed Mania", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Mixed Mania Bipolar Disorder" ], "interventions": [ { "name": "Lamotrigine", "type": "DRUG" }, { "name": "Sodium Valproate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Beth Israel Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 36, "start_date": "2003-07", "completion_date": "2007-07", "has_results": false, "last_update_posted_date": "2010-11-25", "last_synced_at": "2026-10-21T03:27:28.652Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00206778" } ] }