{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=enucleation&page=2",
    "query": {
      "intervention": "enucleation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=enucleation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-14T14:46:44.730Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05155891",
      "title": "Investigation of Prostate Artery Embolization Compared to Holmium Laser Enucleation of Prostate",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Embosphere Microspheres",
          "type": "DEVICE"
        },
        {
          "name": "HoLEP Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "50 Years and older · Male only"
      },
      "enrollment_count": 45,
      "start_date": "2022-06-17",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05155891"
    },
    {
      "nct_id": "NCT07015190",
      "title": "Neoadjuvant Darovasertib in Primary Uveal Melanoma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Uveal Melanoma"
      ],
      "interventions": [
        {
          "name": "Darovasertib",
          "type": "DRUG"
        },
        {
          "name": "Primary Local Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "IDEAYA Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 520,
      "start_date": "2026-01-25",
      "completion_date": "2031-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 35,
      "location_summary": "Scottsdale, Arizona • La Jolla, California • Los Angeles, California + 26 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07015190"
    },
    {
      "nct_id": "NCT00186888",
      "title": "Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Retinoblastoma",
        "Retinal Neoplasm"
      ],
      "interventions": [
        {
          "name": "Enucleation",
          "type": "PROCEDURE"
        },
        {
          "name": "Vincristine, Carboplatin",
          "type": "DRUG"
        },
        {
          "name": "Focal Therapies",
          "type": "PROCEDURE"
        },
        {
          "name": "External Beam Radiation",
          "type": "RADIATION"
        },
        {
          "name": "Vincristine and Topotecan",
          "type": "DRUG"
        },
        {
          "name": "Vincristine + Carboplatin + Etoposide",
          "type": "DRUG"
        },
        {
          "name": "vincristine, cyclophosphamide, and doxorubicin",
          "type": "DRUG"
        },
        {
          "name": "Vincristine, Carboplatin and Etoposide",
          "type": "DRUG"
        },
        {
          "name": "Periocular carboplatin",
          "type": "PROCEDURE"
        },
        {
          "name": "G-CSF",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "RADIATION",
        "OTHER"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 107,
      "start_date": "2005-04-07",
      "completion_date": "2024-11-12",
      "has_results": true,
      "last_update_posted_date": "2025-09-04",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00186888"
    },
    {
      "nct_id": "NCT05719220",
      "title": "Effect of Group Preoperative Pelvic Floor Training for HoLEP",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "BPH",
        "Urinary Incontinence"
      ],
      "interventions": [
        {
          "name": "Group preoperative pelvic floor training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "MALE",
        "summary": "50 Years to 90 Years · Male only"
      },
      "enrollment_count": 100,
      "start_date": "2024-02-07",
      "completion_date": "2028-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05719220"
    },
    {
      "nct_id": "NCT06531473",
      "title": "Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urologic Diseases",
        "Prostate Obstruction"
      ],
      "interventions": [
        {
          "name": "HoLEP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "MALE",
        "summary": "18 Years to 89 Years · Male only"
      },
      "enrollment_count": 278,
      "start_date": "2024-03-04",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06531473"
    },
    {
      "nct_id": "NCT07187180",
      "title": "Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "BPH With Symptomatic Lower Urinary Tract Symptoms",
        "BPH With Urinary Obstruction"
      ],
      "interventions": [
        {
          "name": "holmium laser",
          "type": "DEVICE"
        },
        {
          "name": "pulsed thulium laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smita De",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 50,
      "start_date": "2025-06-02",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-22",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07187180"
    },
    {
      "nct_id": "NCT06179654",
      "title": "Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Benign Prostatic Hyperplasia With Outflow Obstruction",
        "Urinary Retention",
        "Lower Urinary Tract Symptoms"
      ],
      "interventions": [
        {
          "name": "Preoperative pelvic floor physical therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 36,
      "start_date": "2023-11-29",
      "completion_date": "2026-10-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-21",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06179654"
    },
    {
      "nct_id": "NCT07632742",
      "title": "Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Enlarged Prostate (BPH)",
        "Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Magneto 150 holmium laser",
          "type": "DEVICE"
        },
        {
          "name": "Moses 2.0 holmium laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "MALE",
        "summary": "18 Years to 100 Years · Male only"
      },
      "enrollment_count": 180,
      "start_date": "2026-06",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07632742"
    },
    {
      "nct_id": "NCT04826887",
      "title": "SOLTIVE™ Laser Enucleation for Treatment of Benign Prostatic Hyperplasia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "BPH",
        "Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "SOLTIVE Thulium Laser",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care (Holmium Laser)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 15,
      "start_date": "2021-04-14",
      "completion_date": "2024-05-02",
      "has_results": false,
      "last_update_posted_date": "2024-10-02",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04826887"
    },
    {
      "nct_id": "NCT05082142",
      "title": "Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Kidney Calculi",
        "Urologic Diseases",
        "Benign Prostatic Hypertrophy"
      ],
      "interventions": [
        {
          "name": "Tranexamic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "MALE",
        "summary": "18 Years to 89 Years · Male only"
      },
      "enrollment_count": 110,
      "start_date": "2021-09-17",
      "completion_date": "2022-12-14",
      "has_results": true,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-09-14T14:46:44.730Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05082142"
    }
  ]
}