{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=extended+release+niacin", "query": { "intervention": "extended release niacin" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 26, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=extended+release+niacin&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-16T22:26:23.007Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01984073", "title": "Effects of Niacin On Fatty Acid Trapping", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Dyslipidemia" ], "interventions": [ { "name": "ER Niacin Oral Fat Challenge", "type": "DRUG" }, { "name": "IR Niacin Oral Fat Challenge", "type": "DRUG" }, { "name": "Placebo Oral Fat Challenge", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "22 Years to 75 Years" }, "enrollment_count": 26, "start_date": "2012-12", "completion_date": "2019-12", "has_results": false, "last_update_posted_date": "2020-07-09", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 2, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01984073" }, { "nct_id": "NCT00046267", "title": "Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections", "Hypercholesterolemia", "Hypertriglyceridemia", "Diabetes Mellitus" ], "interventions": [ { "name": "Niacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2011-03-02", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 16, "location_summary": "Los Angeles, California • San Diego, California • Stanford, California + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00046267" }, { "nct_id": "NCT04464070", "title": "Pathways of Eicosanoid Metabolism", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Metabolism of Prostaglandin D2" ], "interventions": [ { "name": "niacin", "type": "DIETARY_SUPPLEMENT" }, { "name": "aspirin", "type": "DRUG" }, { "name": "PGD2", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG", "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 10, "start_date": "2020-08-15", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-06-05", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04464070" }, { "nct_id": "NCT01178320", "title": "Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Coronary Artery Disease", "Carotid Artery Diseases", "Atherosclerosis" ], "interventions": [ { "name": "Simvastatin, simvastatin plus extended-release niacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": null, "sex": "ALL", "summary": "45 Years and older" }, "enrollment_count": 230, "start_date": "2008-03", "completion_date": "2015-02", "has_results": false, "last_update_posted_date": "2018-02-09", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 15, "location_summary": "Phoenix, Arizona • Long Beach, California • Los Angeles, California + 7 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01178320" }, { "nct_id": "NCT00300365", "title": "Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metabolic Syndrome" ], "interventions": [ { "name": "Pioglitazone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Niacin ER", "type": "DRUG" }, { "name": "Aspirin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 38, "start_date": "2005-11", "completion_date": "2010-08", "has_results": true, "last_update_posted_date": "2017-07-28", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00300365" }, { "nct_id": "NCT02702492", "title": "PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Solid Tumors", "NHL" ], "interventions": [ { "name": "KPT-9274", "type": "DRUG" }, { "name": "Niacin ER", "type": "DRUG" }, { "name": "Nivolumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Karyopharm Therapeutics Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2016-06-08", "completion_date": "2021-01-26", "has_results": true, "last_update_posted_date": "2024-11-25", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 7, "location_summary": "Los Angeles, California • Aurora, Colorado • Washington D.C., District of Columbia + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02702492" }, { "nct_id": "NCT00687076", "title": "Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Peripheral Arterial Disease" ], "interventions": [ { "name": "Ezetimibe", "type": "DRUG" }, { "name": "Niaspan", "type": "DRUG" }, { "name": "Statin therapy", "type": "DRUG" }, { "name": "Standard care", "type": "BEHAVIORAL" }, { "name": "Aspirin", "type": "DRUG" }, { "name": "Clopidogrel", "type": "DRUG" }, { "name": "Placebo Niaspan", "type": "DRUG" }, { "name": "Placebo Ezetimibe", "type": "DRUG" }, { "name": "Percutaneous transluminal angioplasty (PTA)", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "PROCEDURE" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 102, "start_date": "2004-04", "completion_date": "2010-12", "has_results": true, "last_update_posted_date": "2020-02-06", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00687076" }, { "nct_id": "NCT01221402", "title": "Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Aortocoronary Saphenous Vein Bypass Graft Atherosclerosis", "Intermediate Saphenous Vein Graft Lesions" ], "interventions": [ { "name": "extended-release niacin (Niaspan)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "North Texas Veterans Healthcare System", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 38, "start_date": "2010-10", "completion_date": "2015-11", "has_results": false, "last_update_posted_date": "2017-08-17", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01221402" }, { "nct_id": "NCT00359281", "title": "Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "atorvastatin", "type": "DRUG" }, { "name": "simvastatin", "type": "DRUG" }, { "name": "ezetimibe", "type": "DRUG" }, { "name": "fenofibrate", "type": "DRUG" }, { "name": "dextromethorphan", "type": "DRUG" }, { "name": "Extended Release Niacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aegerion Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 125, "start_date": "2006-03", "completion_date": "2007-11", "has_results": true, "last_update_posted_date": "2018-02-23", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00359281" }, { "nct_id": "NCT00626392", "title": "Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dyslipidemia" ], "interventions": [ { "name": "niacin extended-release (NER)", "type": "DRUG" }, { "name": "aspirin (ASA)", "type": "DRUG" }, { "name": "aspirin placebo (ASA Pbo)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Abbott", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 277, "start_date": "2008-02", "completion_date": "2008-04", "has_results": true, "last_update_posted_date": "2009-09-02", "last_synced_at": "2026-09-16T22:26:23.007Z", "location_count": 26, "location_summary": "Huntsville, Alabama • Scottsdale, Arizona • Tucson, Arizona + 22 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00626392" } ] }