{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=fluid+restriction",
    "query": {
      "intervention": "fluid restriction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=fluid+restriction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T05:57:04.936Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04675775",
      "title": "The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cirrhosis",
        "Ascites",
        "Liver Diseases",
        "Frailty",
        "Sarcopenia",
        "Hepatic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Medically-tailored meals (MTM)",
          "type": "OTHER"
        },
        {
          "name": "Protein supplements",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Nutrition education handout",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2021-01-21",
      "completion_date": "2023-03-05",
      "has_results": true,
      "last_update_posted_date": "2024-03-06",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04675775"
    },
    {
      "nct_id": "NCT00115063",
      "title": "LOSS- Louisiana Obese Subjects Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "group sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "sibutramine, orlistat, diethylpropion",
          "type": "DRUG"
        },
        {
          "name": "Low Calorie Diet, Health One",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensive Medical Combination Therapy for Obesity",
          "type": "OTHER"
        },
        {
          "name": "Control Condition",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Pennington Biomedical Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "20 Years to 60 Years"
      },
      "enrollment_count": 390,
      "start_date": "2005-07",
      "completion_date": "2008-01",
      "has_results": true,
      "last_update_posted_date": "2016-02-22",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00115063"
    },
    {
      "nct_id": "NCT01876706",
      "title": "UroLift System TOlerability and ReCovery When Administering Local Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "UroLift® System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NeoTract, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "50 Years and older · Male only"
      },
      "enrollment_count": 51,
      "start_date": "2013-04",
      "completion_date": "2018-09-04",
      "has_results": true,
      "last_update_posted_date": "2019-03-20",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 7,
      "location_summary": "San Diego, California • Daytona Beach, Florida • St. Petersburg, Florida + 4 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Daytona Beach",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01876706"
    },
    {
      "nct_id": "NCT01428050",
      "title": "The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pancreaticoduodenectomy"
      ],
      "interventions": [
        {
          "name": "3% NaCl Solution",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringers Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 264,
      "start_date": "2011-05",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2015-03-18",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01428050"
    },
    {
      "nct_id": "NCT03137446",
      "title": "Restrictive Intravenous Fluids Trial in Sepsis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Septic Shock",
        "Severe Sepsis"
      ],
      "interventions": [
        {
          "name": "Intravenous Fluid Cap",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rhode Island Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 113,
      "start_date": "2017-04-20",
      "completion_date": "2018-03-30",
      "has_results": false,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03137446"
    },
    {
      "nct_id": "NCT00731978",
      "title": "NIRF Trial: Near-Infrared Spectroscopy for Intraoperative Restriction of Fluids Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Surgery"
      ],
      "interventions": [
        {
          "name": "Restricted intraoperative fluid management",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hutchinson Technology Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2008-09",
      "completion_date": "2009-10",
      "has_results": false,
      "last_update_posted_date": "2009-10-29",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 2,
      "location_summary": "Stanford, California • San Antonio, Texas",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00731978"
    },
    {
      "nct_id": "NCT07653620",
      "title": "Hydration & Female Life Stages",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration",
        "Menstruation",
        "Pre-menopause",
        "Peri-menopausal Women",
        "Post-menopausal Women",
        "Hydration"
      ],
      "interventions": [
        {
          "name": "placebo beverage",
          "type": "OTHER"
        },
        {
          "name": "electrolyte beverage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "PepsiCo Global R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 72,
      "start_date": "2026-06",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 2,
      "location_summary": "Bradenton, Florida • Valhalla, New York",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Valhalla",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07653620"
    },
    {
      "nct_id": "NCT00321269",
      "title": "Depression and Congestive Heart Failure in Outpatients.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Single Illness Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Comorbid Illness Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 134,
      "start_date": "2007-10",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2015-12-24",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa • Columbia, Missouri",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00321269"
    },
    {
      "nct_id": "NCT05547165",
      "title": "Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ductus Arteriosus, Patent"
      ],
      "interventions": [
        {
          "name": "Percutaneous Patent Ductus Arteriosus Closure (PPC)",
          "type": "DEVICE"
        },
        {
          "name": "Responsive Management Intervention",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Echocardiogram, cardiac",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "COMBINATION_PRODUCT",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "32 Days",
        "sex": "ALL",
        "summary": "7 Days to 32 Days"
      },
      "enrollment_count": 240,
      "start_date": "2023-02-21",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-03-30",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 19 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05547165"
    },
    {
      "nct_id": "NCT06107335",
      "title": "Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pre-Eclampsia"
      ],
      "interventions": [
        {
          "name": "Human Albumin (colloid)",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringer's Injection (crystalloid)",
          "type": "DRUG"
        },
        {
          "name": "Edwards HemoSphere monitor with ClearSight-Acumen finger cuff",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2025-07-01",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-09-09T05:57:04.936Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06107335"
    }
  ]
}