{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=fluoride+varnish",
    "query": {
      "intervention": "fluoride varnish"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 43,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=fluoride+varnish&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T10:55:56.885Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00793507",
      "title": "Oral Health Care Early Intervention Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caries"
      ],
      "interventions": [
        {
          "name": "Oral Health Care Early Intervention Project",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "Up to 36 Months"
      },
      "enrollment_count": 1178,
      "start_date": "2008-11",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2013-02-05",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 5,
      "location_summary": "Aurora, Colorado • Delta, Colorado • Fort Collins, Colorado + 2 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Delta",
          "state": "Colorado"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Montrose",
          "state": "Colorado"
        },
        {
          "city": "Thornton",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00793507"
    },
    {
      "nct_id": "NCT04002232",
      "title": "Prevention of Enamel Demineralization Using CPP-ACP-NaF Varnish",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Demineralization"
      ],
      "interventions": [
        {
          "name": "CPP-ACP-NaF varnish",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "10 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2019-07-12",
      "completion_date": "2019-12-05",
      "has_results": false,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04002232"
    },
    {
      "nct_id": "NCT00067353",
      "title": "Yakima Head Start Fluoride Varnish Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Fluoride varnish",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "36 Months",
        "maximum_age": "71 Months",
        "sex": "ALL",
        "summary": "36 Months to 71 Months"
      },
      "enrollment_count": 500,
      "start_date": "2003-11",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2010-05-10",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 2,
      "location_summary": "Lower Valley, Yakima County, Washington",
      "locations": [
        {
          "city": "Lower Valley, Yakima County",
          "state": "Washington"
        },
        {
          "city": "Lower Valley, Yakima County",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00067353"
    },
    {
      "nct_id": "NCT03770286",
      "title": "Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries in Children",
        "Dental Caries Class II",
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "5% Fluoride Varnish",
          "type": "DEVICE"
        },
        {
          "name": "38% Silver diamine fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Super Floss",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "3 Years to 12 Years"
      },
      "enrollment_count": 51,
      "start_date": "2019-01-22",
      "completion_date": "2023-05-31",
      "has_results": true,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03770286"
    },
    {
      "nct_id": "NCT04933331",
      "title": "Early Caries Lesion Management Observational Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Initial Caries",
        "Arrested Dental Caries",
        "Cavitated Caries",
        "Dental Caries",
        "Dental Caries in Children"
      ],
      "interventions": [
        {
          "name": "Curodont Repair Fluoride Plus",
          "type": "DRUG"
        },
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer Sealant",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride varnish",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "CareQuest Institute for Oral Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 744,
      "start_date": "2020-12-07",
      "completion_date": "2024-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-24",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 4,
      "location_summary": "Dothan, Alabama • Westborough, Massachusetts • Bend, Oregon + 1 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Westborough",
          "state": "Massachusetts"
        },
        {
          "city": "Bend",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04933331"
    },
    {
      "nct_id": "NCT02645617",
      "title": "Safety Evaluation of Advantage Anti-Caries Varnish",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Varnish",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Advantage Dental Services, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "36 Months",
        "maximum_age": "60 Months",
        "sex": "ALL",
        "summary": "36 Months to 60 Months"
      },
      "enrollment_count": 12,
      "start_date": "2016-03-30",
      "completion_date": "2016-10-20",
      "has_results": true,
      "last_update_posted_date": "2020-01-21",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02645617"
    },
    {
      "nct_id": "NCT01176396",
      "title": "CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Caries prevention active intervention",
          "type": "OTHER"
        },
        {
          "name": "control treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "12 Years to 65 Years"
      },
      "enrollment_count": 460,
      "start_date": "2012-04",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2020-04-10",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01176396"
    },
    {
      "nct_id": "NCT00497029",
      "title": "Early Childhood Caries Prevention at a Pediatric Clinic",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "fluoride varnish",
          "type": "DRUG"
        },
        {
          "name": "patient education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "27 Months",
        "sex": "ALL",
        "summary": "6 Months to 27 Months"
      },
      "enrollment_count": 219,
      "start_date": "2004-06",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2023-05-08",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00497029"
    },
    {
      "nct_id": "NCT02191943",
      "title": "Lesion Progression of Approximal Caries After Resin Infiltration",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Proximal Caries"
      ],
      "interventions": [
        {
          "name": "Duraphat",
          "type": "DEVICE"
        },
        {
          "name": "Icon approximal caries infiltration kit",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DMG Dental Material Gesellschaft mbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-11",
      "completion_date": "2019-12",
      "has_results": false,
      "last_update_posted_date": "2015-01-26",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02191943"
    },
    {
      "nct_id": "NCT03916926",
      "title": "Older Adult Effectiveness of 2 Treatments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "A \"simple medical strategy\" consisting of silver diamine fluoride (SDF)",
          "type": "DEVICE"
        },
        {
          "name": "B \"typical dental strategy\" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "62 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "62 Years and older"
      },
      "enrollment_count": 568,
      "start_date": "2019-09-18",
      "completion_date": "2024-06-07",
      "has_results": true,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-09-09T10:55:56.885Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03916926"
    }
  ]
}