{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=gum+chewing&page=6",
    "query": {
      "intervention": "gum chewing",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 127,
    "total_pages": 13,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=gum+chewing&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=gum+chewing&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T11:36:23.330Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07714200",
      "title": "Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Smoking Cessation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Replacement Therapy",
          "type": "DRUG"
        },
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Mobile Contingency Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Clinic-Based Smoking Cessation Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2027-03-01",
      "completion_date": "2030-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07714200"
    },
    {
      "nct_id": "NCT02994082",
      "title": "Treating Smokeless Tobacco Use in Rural Veterans",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Tailored behavioral intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral activation for elevated depressive symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Post-cessation weight gain management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alcohol use risk reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine replacement therapy - transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Bupropion sustained release",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine replacement therapy",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine replacement therapy + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Tobacco quit line",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational materials",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Mark Vander Weg",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 123,
      "start_date": "2016-12",
      "completion_date": "2020-05",
      "has_results": false,
      "last_update_posted_date": "2019-07-24",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02994082"
    },
    {
      "nct_id": "NCT03719391",
      "title": "United States Pre-Market Tobacco Application Pharmacokinetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Nicotine Dependence, Cigarettes",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Virginia Tobacco flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Cool Mint flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Mango flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Creme Brulee flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "VUSE Solo e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicorette White Ice Mint 4mg nicotine polacrilex gum",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand combustible cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 67,
      "start_date": "2018-10-19",
      "completion_date": "2018-11-28",
      "has_results": false,
      "last_update_posted_date": "2021-06-14",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03719391"
    },
    {
      "nct_id": "NCT04971954",
      "title": "Using Nicotine to Reverse Age-related Auditory Processing Deficits",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Auditory Perceptual Impairment",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Nicotine gum",
          "type": "OTHER"
        },
        {
          "name": "Placebo gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 48,
      "start_date": "2022-02-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-19",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 2,
      "location_summary": "Irvine, California • San Diego, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04971954"
    },
    {
      "nct_id": "NCT04273841",
      "title": "Impact of Sleep Deprivation and Caffeine in Medical Professionals",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Deprivation",
        "Performance"
      ],
      "interventions": [
        {
          "name": "Military Energy Gum",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Gum",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Walter Reed Army Institute of Research (WRAIR)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 7,
      "start_date": "2017-07-06",
      "completion_date": "2024-07-09",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Silver Spring, Maryland",
      "locations": [
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04273841"
    },
    {
      "nct_id": "NCT04490057",
      "title": "A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler",
          "type": "DRUG"
        },
        {
          "name": "Varenicline or bupropion",
          "type": "DRUG"
        },
        {
          "name": "Contingency Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 323,
      "start_date": "2020-07-27",
      "completion_date": "2025-10-24",
      "has_results": true,
      "last_update_posted_date": "2026-01-05",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 4,
      "location_summary": "Bridgeport, Connecticut • New Haven, Connecticut • Brooklyn, New York + 1 more",
      "locations": [
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04490057"
    },
    {
      "nct_id": "NCT07075575",
      "title": "Quit-Smoking Study for Native Hawaiians",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Disorder",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine Polacrilex Gum (2 mg)",
          "type": "DRUG"
        },
        {
          "name": "Cognitive Behavioral Group Therapy (CBGT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Hawaii",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 75,
      "start_date": "2026-04-01",
      "completion_date": "2028-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Honolulu, Hawaii",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07075575"
    },
    {
      "nct_id": "NCT00403377",
      "title": "Investigation of a Behavioral Substitute for Sunbathing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Melanoma (Skin)",
        "Skin Cancer"
      ],
      "interventions": [
        {
          "name": "Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "18 Years to 120 Years"
      },
      "enrollment_count": 307,
      "start_date": "2006-04",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2015-10-01",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00403377"
    },
    {
      "nct_id": "NCT02956616",
      "title": "Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cesarean Section"
      ],
      "interventions": [
        {
          "name": "ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Chewing Gum",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Recovery Protocol",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 118,
      "start_date": "2017-09-01",
      "completion_date": "2018-06-15",
      "has_results": true,
      "last_update_posted_date": "2019-04-25",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02956616"
    },
    {
      "nct_id": "NCT02250924",
      "title": "Caffeinated Gum to Prevent Post-Operative Ileus: A Prospective, Randomized, Placebo-controlled Trial",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "C.Surgical Procedure; Digestive System"
      ],
      "interventions": [
        {
          "name": "Caffeine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Gum",
          "type": "OTHER"
        },
        {
          "name": "wear silicone bracelet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "The Guthrie Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-01",
      "completion_date": "2020-05-28",
      "has_results": false,
      "last_update_posted_date": "2020-06-04",
      "last_synced_at": "2026-11-15T11:36:23.330Z",
      "location_count": 1,
      "location_summary": "Sayre, Pennsylvania",
      "locations": [
        {
          "city": "Sayre",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02250924"
    }
  ]
}