{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=high+dose+FDC+placebo", "query": { "intervention": "high dose FDC placebo" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=high+dose+FDC+placebo&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-21T15:45:48.049Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03337308", "title": "A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hyperlipidemias" ], "interventions": [ { "name": "Bempedoic Acid + Ezetimibe Fixed-Dose Combination", "type": "COMBINATION_PRODUCT" }, { "name": "Bempedoic Acid", "type": "DRUG" }, { "name": "Ezetimibe", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "COMBINATION_PRODUCT", "DRUG" ], "sponsor": "Esperion Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 382, "start_date": "2017-10-23", "completion_date": "2018-07-18", "has_results": true, "last_update_posted_date": "2020-04-08", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 5, "location_summary": "Ames, Iowa • Nashua, New Hampshire • Statesville, North Carolina + 2 more", "locations": [ { "city": "Ames", "state": "Iowa" }, { "city": "Nashua", "state": "New Hampshire" }, { "city": "Statesville", "state": "North Carolina" }, { "city": "Wilmington", "state": "North Carolina" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03337308" }, { "nct_id": "NCT01559116", "title": "Characterization of 24-hour Lung Function Profiles of Inhaled Tiotropium + Olodaterol Fixed Dose Combination in Patients Suffering From Chronic Obstructive Pulmonary Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "tiotropium + olodaterol", "type": "DRUG" }, { "name": "tiotropium", "type": "DRUG" }, { "name": "olodaterol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Respimat", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 219, "start_date": "2012-03", "completion_date": "2013-08", "has_results": true, "last_update_posted_date": "2015-07-16", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 4, "location_summary": "Jasper, Alabama • Easley, South Carolina • Greenville, South Carolina + 1 more", "locations": [ { "city": "Jasper", "state": "Alabama" }, { "city": "Easley", "state": "South Carolina" }, { "city": "Greenville", "state": "South Carolina" }, { "city": "Spartanburg", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01559116" }, { "nct_id": "NCT01422876", "title": "Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "high dose FDC", "type": "DRUG" }, { "name": "BI 10773 high dose", "type": "DRUG" }, { "name": "high dose FDC placebo", "type": "DRUG" }, { "name": "low dose FDC placebo", "type": "DRUG" }, { "name": "high dose BI 10773 placebo", "type": "DRUG" }, { "name": "low dose FDC", "type": "DRUG" }, { "name": "BI 10773 low dose", "type": "DRUG" }, { "name": "linagliptin", "type": "DRUG" }, { "name": "linagliptin placebo", "type": "DRUG" }, { "name": "BI 10773 low dose placebo", "type": "DRUG" }, { "name": "low dose BI 10773 placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1405, "start_date": "2011-08", "completion_date": "2013-09", "has_results": true, "last_update_posted_date": "2015-04-02", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 112, "location_summary": "Birmingham, Alabama • Foley, Alabama • Mobile, Alabama + 90 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Foley", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Pell City", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01422876" }, { "nct_id": "NCT05800015", "title": "A Trial to Learn How the Combination of Fianlimab With Cemiplimab and Chemotherapy Works Compared With Cemiplimab and Chemotherapy for Treating Adult Patients With Advanced Non-small Cell Lung Cancer", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Non-small Cell Lung Cancer" ], "interventions": [ { "name": "fianlimab", "type": "DRUG" }, { "name": "cemiplimab", "type": "DRUG" }, { "name": "Pemetrexed", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 160, "start_date": "2023-08-08", "completion_date": "2031-12-23", "has_results": false, "last_update_posted_date": "2026-07-15", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 29, "location_summary": "Tucson, Arizona • Yuma, Arizona • Cerritos, California + 24 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Yuma", "state": "Arizona" }, { "city": "Cerritos", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05800015" }, { "nct_id": "NCT05608291", "title": "A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Melanoma" ], "interventions": [ { "name": "Fianlimab", "type": "DRUG" }, { "name": "Cemiplimab", "type": "DRUG" }, { "name": "Pembrolizumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 1564, "start_date": "2023-01-16", "completion_date": "2030-04-03", "has_results": false, "last_update_posted_date": "2026-07-06", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 28, "location_summary": "La Jolla, California • San Francisco, California • Santa Monica, California + 21 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Englewood", "state": "Colorado" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05608291" }, { "nct_id": "NCT03531905", "title": "Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes", "Diabetes Mellitus, Type 2", "Cholesterolemia" ], "interventions": [ { "name": "Bempedoic acid + Ezetimibe FDC Oral Tablet", "type": "DRUG" }, { "name": "Ezetimibe 10 mg Oral Tablet", "type": "DRUG" }, { "name": "Placebo Oral Tablet", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Esperion Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 242, "start_date": "2018-05-09", "completion_date": "2019-06-18", "has_results": true, "last_update_posted_date": "2020-04-09", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 4, "location_summary": "Lincoln, California • Miami, Florida • Louisville, Kentucky + 1 more", "locations": [ { "city": "Lincoln", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Suffolk", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03531905" }, { "nct_id": "NCT01525615", "title": "A Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Respimat inhaler", "type": "DEVICE" }, { "name": "tiotropium+olodaterol (low dose)", "type": "DRUG" }, { "name": "tiotropium + olodaterol (high dose)", "type": "DRUG" }, { "name": "placebo to tiotropium+olodaterol", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "40 Years to 75 Years" }, "enrollment_count": 404, "start_date": "2012-02", "completion_date": "2013-09", "has_results": true, "last_update_posted_date": "2016-08-29", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 15, "location_summary": "Torrance, California • Hartford, Connecticut • Springfield, Illinois + 12 more", "locations": [ { "city": "Torrance", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Springfield", "state": "Illinois" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Livonia", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01525615" }, { "nct_id": "NCT02006732", "title": "Tiotropium+Olodaterol Fixed Dose Combination (FDC) in Chronic Obstructive Pulmonary Disease (OTEMTO 2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "olodaterol", "type": "DRUG" }, { "name": "tiotropium", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 809, "start_date": "2013-11", "completion_date": "2014-11", "has_results": true, "last_update_posted_date": "2016-01-20", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 20, "location_summary": "Jasper, Alabama • Stamford, Connecticut • Clearwater, Florida + 17 more", "locations": [ { "city": "Jasper", "state": "Alabama" }, { "city": "Stamford", "state": "Connecticut" }, { "city": "Clearwater", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "Duluth", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02006732" }, { "nct_id": "NCT01533922", "title": "Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Tiotropium", "type": "DRUG" }, { "name": "Olodaterol", "type": "DRUG" }, { "name": "Tiotropium + Olodaterol", "type": "DRUG" }, { "name": "Respimat", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "40 Years to 75 Years" }, "enrollment_count": 295, "start_date": "2012-03", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2015-09-15", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 8, "location_summary": "Torrance, California • Hartford, Connecticut • Livonia, Michigan + 5 more", "locations": [ { "city": "Torrance", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Livonia", "state": "Michigan" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Easley", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01533922" }, { "nct_id": "NCT01964352", "title": "Tiotropium + Olodaterol Fixed Dose Combination (FDC) in Chronic Obstructive Pulmonary Disease (OTEMTO 1)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "tiotropium", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" }, { "name": "olodaterol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 813, "start_date": "2013-11", "completion_date": "2014-11", "has_results": true, "last_update_posted_date": "2015-11-25", "last_synced_at": "2026-09-21T15:45:48.049Z", "location_count": 20, "location_summary": "Wheat Ridge, Colorado • Clearwater, Florida • Panama City, Florida + 17 more", "locations": [ { "city": "Wheat Ridge", "state": "Colorado" }, { "city": "Clearwater", "state": "Florida" }, { "city": "Panama City", "state": "Florida" }, { "city": "Coeur d'Alene", "state": "Idaho" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01964352" } ] }