{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=hyperbaric+bupivacaine",
    "query": {
      "intervention": "hyperbaric bupivacaine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=hyperbaric+bupivacaine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T12:51:13.166Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00804609",
      "title": "Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epidural Analgesia, Obstetric"
      ],
      "interventions": [
        {
          "name": "DepoDur following epidural lidocaine",
          "type": "DRUG"
        },
        {
          "name": "DepoDur following spinal anesthetic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2008-09",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2017-10-12",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00804609"
    },
    {
      "nct_id": "NCT03967288",
      "title": "Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia, Spinal"
      ],
      "interventions": [
        {
          "name": "Chloroprocaine Injection [Clorotekal]",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride 0.75% Injection Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 27,
      "start_date": "2019-10-24",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03967288"
    },
    {
      "nct_id": "NCT06291727",
      "title": "Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia, Spinal",
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Mepivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 138,
      "start_date": "2024-02-16",
      "completion_date": "2025-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06291727"
    },
    {
      "nct_id": "NCT03324984",
      "title": "1% Chloroprocaine(PF) vs. Bupivacaine Spinals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Return of Motor and Sensory Blockade",
        "Anesthesia, Spinal",
        "Decrease Discharge Time Status Post Hemorrhoidectomy"
      ],
      "interventions": [
        {
          "name": "1% chloroprocaine",
          "type": "DRUG"
        },
        {
          "name": "0.75% bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2019-09-11",
      "completion_date": "2023-02-01",
      "has_results": true,
      "last_update_posted_date": "2025-02-28",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03324984"
    },
    {
      "nct_id": "NCT03948386",
      "title": "3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Osteoarthritis, Hip"
      ],
      "interventions": [
        {
          "name": "isobaric bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "hyperbaric bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "isobaric mepivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "18 Years to 84 Years"
      },
      "enrollment_count": 159,
      "start_date": "2019-05-13",
      "completion_date": "2019-11-11",
      "has_results": true,
      "last_update_posted_date": "2021-05-07",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 2,
      "location_summary": "Bensalem, Pennsylvania • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Bensalem",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03948386"
    },
    {
      "nct_id": "NCT03226080",
      "title": "GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hip Fractures",
        "Anesthesia, Spinal",
        "Anesthesia, General",
        "Neuromuscular Blockade"
      ],
      "interventions": [
        {
          "name": "Rocuronium",
          "type": "DRUG"
        },
        {
          "name": "Sugammadex",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loyola University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-07-19",
      "completion_date": "2020-08",
      "has_results": false,
      "last_update_posted_date": "2019-08-20",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Maywood, Illinois",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03226080"
    },
    {
      "nct_id": "NCT02369510",
      "title": "Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Spinal Anesthesia",
        "Cesarean Section"
      ],
      "interventions": [
        {
          "name": "Low-dose epinephrine",
          "type": "DRUG"
        },
        {
          "name": "High-dose epinephrine",
          "type": "DRUG"
        },
        {
          "name": "No epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 68,
      "start_date": "2015-02",
      "completion_date": "2016-05",
      "has_results": true,
      "last_update_posted_date": "2017-08-30",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02369510"
    },
    {
      "nct_id": "NCT00990574",
      "title": "A Study Comparing Two Spinal Techniques for for Cesarean Delivery Anesthesia",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypotension",
        "Headache"
      ],
      "interventions": [
        {
          "name": "Wiley Spinal Catheter",
          "type": "DEVICE"
        },
        {
          "name": "Spinal Anesthesia Group (SAG)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2009-10",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-10-08",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00990574"
    },
    {
      "nct_id": "NCT03781388",
      "title": "ED90 for Hyperbaric Bupivacaine in Super Obese Parturients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obesity, Morbid",
        "Spinal Anesthesia",
        "Cesarean Delivery"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2019-05-01",
      "completion_date": "2022-12-06",
      "has_results": true,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03781388"
    },
    {
      "nct_id": "NCT02277782",
      "title": "Intrathecal Hydromorphone for Labor Analgesia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Hydromorphone",
          "type": "DRUG"
        },
        {
          "name": "Hyperbaric bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2015-09-01",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-03-18",
      "last_synced_at": "2026-09-23T12:51:13.166Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02277782"
    }
  ]
}