{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=iLet-based+bionic+pancreas",
    "query": {
      "intervention": "iLet-based bionic pancreas"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T00:14:26.791Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06449677",
      "title": "Bionic Pancreas in CFRD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cystic Fibrosis-related Diabetes"
      ],
      "interventions": [
        {
          "name": "iLet Bionic Pancreas System (BP)",
          "type": "DEVICE"
        },
        {
          "name": "Usual Care (UC)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2024-09-24",
      "completion_date": "2027-03-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 16,
      "location_summary": "Aurora, Colorado • New Haven, Connecticut • Atlanta, Georgia + 13 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06449677"
    },
    {
      "nct_id": "NCT04200313",
      "title": "The Insulin-Only Bionic Pancreas Pivotal Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus",
        "Type 1 Diabetes",
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Bionic Pancreas (BP) with Aspart or Lispro",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Bionic Pancreas with Fiasp (BPFiasp)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Usual Care (UC)",
          "type": "OTHER"
        },
        {
          "name": "BP Guidance Insulin Dosing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "OTHER"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 440,
      "start_date": "2020-03-31",
      "completion_date": "2022-01-14",
      "has_results": true,
      "last_update_posted_date": "2025-02-20",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 16,
      "location_summary": "Orange, California • San Diego, California • Stanford, California + 13 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04200313"
    },
    {
      "nct_id": "NCT03840278",
      "title": "The Bihormonal iLet Bionic Pancreas Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Bihormonal iLet Bionic Pancreas",
          "type": "DEVICE"
        },
        {
          "name": "Insulin-only Bionic Pancreas",
          "type": "DEVICE"
        },
        {
          "name": "Dasiglucagon",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2019-05-15",
      "completion_date": "2019-07-03",
      "has_results": true,
      "last_update_posted_date": "2019-12-16",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03840278"
    },
    {
      "nct_id": "NCT02701257",
      "title": "The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus Type 1"
      ],
      "interventions": [
        {
          "name": "iPhone bionic pancreas",
          "type": "DEVICE"
        },
        {
          "name": "iLet bionic pancreas",
          "type": "DEVICE"
        },
        {
          "name": "Xeris Xerisol glucagon",
          "type": "DRUG"
        },
        {
          "name": "Lilly glucagon",
          "type": "DRUG"
        },
        {
          "name": "iLet infusion set",
          "type": "DEVICE"
        },
        {
          "name": "Contact Detach infusion set",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2016-03",
      "completion_date": "2018-05",
      "has_results": true,
      "last_update_posted_date": "2019-11-18",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02701257"
    },
    {
      "nct_id": "NCT05168657",
      "title": "Feasibility of Closed-loop Automated Insulin Delivery System by Primary Care & Endocrinology, in Person & Via Telehealth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1",
        "Type 1 Diabetes",
        "Diabetes, Autoimmune",
        "Diabetes type1",
        "Autoimmune Diabetes",
        "Diabetes Mellitus, Brittle",
        "Diabetes Mellitus, Insulin-Dependent",
        "Diabetes Mellitus, Insulin-Dependent, 1",
        "Diabetes Mellitus, Juvenile-Onset",
        "Diabetes Mellitus, Ketosis-Prone",
        "Diabetes Mellitus, Sudden-Onset",
        "Insulin-Dependent Diabetes Mellitus 1",
        "Juvenile-Onset Diabetes",
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Bionic Pancreas",
          "type": "DEVICE"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 54,
      "start_date": "2022-03-31",
      "completion_date": "2023-05-23",
      "has_results": true,
      "last_update_posted_date": "2024-10-21",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Boston, Massachusetts",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05168657"
    },
    {
      "nct_id": "NCT03816761",
      "title": "Research Study to Look at Fast-acting Insulin Aspart With the Insulin Pump System 'iLet™' in Adults With Type 1 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Fast-acting insulin aspart",
          "type": "DRUG"
        },
        {
          "name": "iLet™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Novo Nordisk A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 24,
      "start_date": "2019-02-25",
      "completion_date": "2019-06-10",
      "has_results": true,
      "last_update_posted_date": "2020-06-11",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03816761"
    },
    {
      "nct_id": "NCT02971228",
      "title": "Feasibility Trial Testing the Bionic Pancreas With ZP4207",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Insulin Lispro",
          "type": "DRUG"
        },
        {
          "name": "ZP4207 (dasiglucagon)",
          "type": "DRUG"
        },
        {
          "name": "Glucagon",
          "type": "DRUG"
        },
        {
          "name": "iPhone-based bionic pancreas",
          "type": "DEVICE"
        },
        {
          "name": "iLet-based bionic pancreas",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Zealand Pharma",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2016-11",
      "completion_date": "2017-06-07",
      "has_results": true,
      "last_update_posted_date": "2021-03-23",
      "last_synced_at": "2026-09-04T00:14:26.791Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02971228"
    }
  ]
}