{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=iNO", "query": { "intervention": "iNO" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 202, "total_pages": 21, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=iNO&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T05:34:22.164Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00000891", "title": "Immunologic and Virologic Consequences of Long-Term Highly Active Antiretroviral Therapy (HAART) in Subjects With Moderately Advanced HIV-1 Disease: A Follow-Up Study to ACTG 315", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Ritonavir", "type": "DRUG" }, { "name": "Saquinavir", "type": "DRUG" }, { "name": "Delavirdine mesylate", "type": "DRUG" }, { "name": "Lamivudine", "type": "DRUG" }, { "name": "Stavudine", "type": "DRUG" }, { "name": "Zidovudine", "type": "DRUG" }, { "name": "Didanosine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 34, "start_date": null, "completion_date": "2004-05", "has_results": false, "last_update_posted_date": "2021-11-04", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 3, "location_summary": "Denver, Colorado • Chicago, Illinois • Cleveland, Ohio", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000891" }, { "nct_id": "NCT01022580", "title": "Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bronchopulmonary Dysplasia" ], "interventions": [ { "name": "Infasurf surfactant (ONY, Inc.)", "type": "DRUG" }, { "name": "Sham (No Treatment)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Roberta Ballard", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Days", "maximum_age": "14 Days", "sex": "ALL", "summary": "7 Days to 14 Days" }, "enrollment_count": 511, "start_date": "2010-01", "completion_date": "2016-01", "has_results": true, "last_update_posted_date": "2021-05-13", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 21, "location_summary": "Little Rock, Arkansas • Berkeley, California • Oakland, California + 15 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Berkeley", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01022580" }, { "nct_id": "NCT01891500", "title": "Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Persistent Fetal Circulation Syndrome", "Hypertension, Pulmonary, of Newborn, Persistent", "Persistent Pulmonary Hypertension of Newborn" ], "interventions": [ { "name": "Inhaled nitric oxide", "type": "DRUG" }, { "name": "Nitrogen Gas", "type": "DRUG" }, { "name": "Crossover iNO", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Minutes", "maximum_age": "48 Hours", "sex": "ALL", "summary": "30 Minutes to 48 Hours" }, "enrollment_count": 0, "start_date": "2016-05", "completion_date": "2019-09-19", "has_results": false, "last_update_posted_date": "2020-01-07", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01891500" }, { "nct_id": "NCT01529502", "title": "Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Blood Transfusion", "Endothelial Physiopathology", "Nitric Oxide", "Pulmonary Hypertension" ], "interventions": [ { "name": "Red blood Cells auto-transfusion", "type": "PROCEDURE" }, { "name": "Inhaled Nitric Oxide (iNO) administration", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 14, "start_date": "2012-03", "completion_date": "2013-12", "has_results": true, "last_update_posted_date": "2017-05-22", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01529502" }, { "nct_id": "NCT00001048", "title": "Comparison of Anti HIV Drugs Used Alone or in Combination With Cytosine Arabinoside to Treat Progressive Multifocal Leukoencephalopathy (PML) in HIV-Infected Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV Infections", "Leukoencephalopathy, Progressive Multifocal" ], "interventions": [ { "name": "Filgrastim", "type": "DRUG" }, { "name": "Cytarabine", "type": "DRUG" }, { "name": "Zidovudine", "type": "DRUG" }, { "name": "Zalcitabine", "type": "DRUG" }, { "name": "Didanosine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 90, "start_date": null, "completion_date": "1997-04", "has_results": false, "last_update_posted_date": "2021-11-01", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 9, "location_summary": "Aurora, Colorado • Miami, Florida • Chicago, Illinois + 6 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Miami", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001048" }, { "nct_id": "NCT00000885", "title": "Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination With Nucleoside Analogs: A Rollover Study for ACTG 320", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Indinavir sulfate", "type": "DRUG" }, { "name": "Abacavir sulfate", "type": "DRUG" }, { "name": "Nelfinavir mesylate", "type": "DRUG" }, { "name": "Efavirenz", "type": "DRUG" }, { "name": "Levocarnitine", "type": "DRUG" }, { "name": "Adefovir dipivoxil", "type": "DRUG" }, { "name": "Lamivudine", "type": "DRUG" }, { "name": "Stavudine", "type": "DRUG" }, { "name": "Zidovudine", "type": "DRUG" }, { "name": "Didanosine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 440, "start_date": null, "completion_date": "2003-06", "has_results": false, "last_update_posted_date": "2021-10-28", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 52, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 32 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Jose", "state": "California" }, { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000885" }, { "nct_id": "NCT04398290", "title": "iNOPulse for COVID-19", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19", "Hypoxemia", "Hypoxemic Respiratory Failure" ], "interventions": [ { "name": "Inhaled nitric oxide (iNO)", "type": "DRUG" }, { "name": "Nitrogen gas", "type": "DRUG" }, { "name": "Oxygen gas", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Roger Alvarez", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2020-12-01", "completion_date": "2021-07-15", "has_results": false, "last_update_posted_date": "2020-08-19", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04398290" }, { "nct_id": "NCT00000902", "title": "A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children With Prior Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Ritonavir", "type": "DRUG" }, { "name": "Nelfinavir mesylate", "type": "DRUG" }, { "name": "Nevirapine", "type": "DRUG" }, { "name": "Lamivudine", "type": "DRUG" }, { "name": "Stavudine", "type": "DRUG" }, { "name": "Zidovudine", "type": "DRUG" }, { "name": "Zalcitabine", "type": "DRUG" }, { "name": "Didanosine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "21 Years", "sex": "ALL", "summary": "6 Months to 21 Years" }, "enrollment_count": 217, "start_date": null, "completion_date": "2002-04", "has_results": false, "last_update_posted_date": "2021-10-29", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 59, "location_summary": "Birmingham, Alabama • Mobile, Alabama • La Jolla, California + 42 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "La Jolla", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000902" }, { "nct_id": "NCT00000814", "title": "A Comparative Study of Combination Antiretroviral Therapy in Children and Adolescents With Advanced HIV Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Nevirapine", "type": "DRUG" }, { "name": "Zidovudine", "type": "DRUG" }, { "name": "Didanosine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "20 Years", "sex": "ALL", "summary": "6 Months to 20 Years" }, "enrollment_count": 390, "start_date": null, "completion_date": "1998-11", "has_results": false, "last_update_posted_date": "2021-10-28", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 65, "location_summary": "Birmingham, Alabama • La Jolla, California • Long Beach, California + 40 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "La Jolla", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000814" }, { "nct_id": "NCT00002060", "title": "A Multi-Center Randomized Double-Blind Placebo-Controlled Study To Investigate the Effect of Isoprinosine in Patients With AIDS Related Complex (ARC)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Inosine pranobex", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Newport Pharmaceuticals International", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "MALE", "summary": "18 Years to 75 Years · Male only" }, "enrollment_count": null, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-09-02T05:34:22.164Z", "location_count": 1, "location_summary": "Laguna Hills, California", "locations": [ { "city": "Laguna Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002060" } ] }