{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ibuprofen+600+mg+tid",
    "query": {
      "intervention": "ibuprofen 600 mg tid"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-01T16:39:05.454Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00662896",
      "title": "To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteoarthritis",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "naproxcinod 375 mg bid",
          "type": "DRUG"
        },
        {
          "name": "naproxcinod 750 mg bid",
          "type": "DRUG"
        },
        {
          "name": "naproxen 250 mg bid",
          "type": "DRUG"
        },
        {
          "name": "naproxen 500 mg bid",
          "type": "DRUG"
        },
        {
          "name": "ibuprofen 600 mg tid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NicOx",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2008-03",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2011-06-17",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 57,
      "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Sierra Vista, Arizona + 54 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Sierra Vista",
          "state": "Arizona"
        },
        {
          "city": "Carmichael",
          "state": "California"
        },
        {
          "city": "Fair Oaks",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00662896"
    },
    {
      "nct_id": "NCT02006576",
      "title": "Prostaglandin Inhibition for Emphysema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Emphysema"
      ],
      "interventions": [
        {
          "name": "600 mg ibuprofen three times daily for 48 weeks",
          "type": "DRUG"
        },
        {
          "name": "Placebo three times daily",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "46 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "46 Years to 80 Years"
      },
      "enrollment_count": 118,
      "start_date": "2014-01-01",
      "completion_date": "2018-03-31",
      "has_results": true,
      "last_update_posted_date": "2023-12-13",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 5,
      "location_summary": "Birmingham, Alabama • Torrance, California • Denver, Colorado + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02006576"
    },
    {
      "nct_id": "NCT02915055",
      "title": "NSAID vs. Narcotics",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Multimodal Analgesia",
        "Nonsteroidal Anti-inflammatory Drugs"
      ],
      "interventions": [
        {
          "name": "Ibuprofen 600 mg",
          "type": "DRUG"
        },
        {
          "name": "standard oxycodone/acetaminophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 77,
      "start_date": "2016-09-01",
      "completion_date": "2017-03-01",
      "has_results": false,
      "last_update_posted_date": "2017-05-08",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02915055"
    },
    {
      "nct_id": "NCT04018768",
      "title": "Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "ibuprofen 600 mg",
          "type": "OTHER"
        },
        {
          "name": "Oxycodone/acetaminophen (Percocet) 5 mg/325",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2017-12-01",
      "completion_date": "2019-02-01",
      "has_results": false,
      "last_update_posted_date": "2020-05-29",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04018768"
    },
    {
      "nct_id": "NCT00267176",
      "title": "Safety and Efficacy of Lumiracoxib in Patients With Osteoarthritis and With Controlled Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Osteoarthritis",
        "Controlled Hypertension"
      ],
      "interventions": [
        {
          "name": "lumiracoxib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 1020,
      "start_date": "2005-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-02-07",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 1,
      "location_summary": "O'Fallon, Illinois",
      "locations": [
        {
          "city": "O'Fallon",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00267176"
    },
    {
      "nct_id": "NCT03243032",
      "title": "Pre-Emptive Analgesia in Dental Implant Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Ibuprofen 600 mg",
          "type": "DRUG"
        },
        {
          "name": "Local anesthetic Group 1",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral capsule",
          "type": "DRUG"
        },
        {
          "name": "Local anesthetic Control",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Satheesh Elangovan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-10-06",
      "completion_date": "2017-11-06",
      "has_results": false,
      "last_update_posted_date": "2018-10-12",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03243032"
    },
    {
      "nct_id": "NCT00346216",
      "title": "Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arthritis, Rheumatoid"
      ],
      "interventions": [
        {
          "name": "celecoxib",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Naproxen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer's Upjohn has merged with Mylan to form Viatris Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24081,
      "start_date": "2006-10-04",
      "completion_date": "2016-04-12",
      "has_results": true,
      "last_update_posted_date": "2021-03-03",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 871,
      "location_summary": "Alabaster, Alabama • Bessemer, Alabama • Birmingham, Alabama + 515 more",
      "locations": [
        {
          "city": "Alabaster",
          "state": "Alabama"
        },
        {
          "city": "Bessemer",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00346216"
    },
    {
      "nct_id": "NCT04102566",
      "title": "Optimizing Pain Control in Transurethral Resection of the Prostate",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain",
        "BPH With Urinary Obstruction",
        "BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms"
      ],
      "interventions": [
        {
          "name": "Ibuprofen 600 mg",
          "type": "DRUG"
        },
        {
          "name": "Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Benaroya Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 50,
      "start_date": "2017-12-08",
      "completion_date": "2019-12-01",
      "has_results": false,
      "last_update_posted_date": "2019-09-27",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04102566"
    },
    {
      "nct_id": "NCT07006675",
      "title": "Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tibial Fractures",
        "Pain"
      ],
      "interventions": [
        {
          "name": "600 mg Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2021-05-26",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-10-01T16:39:05.454Z",
      "location_count": 13,
      "location_summary": "Indianapolis, Indiana • Baltimore, Maryland • Cambridge, Massachusetts + 9 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07006675"
    }
  ]
}