{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ingenol+mebutate", "query": { "intervention": "ingenol mebutate" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 33, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ingenol+mebutate&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T03:30:43.625Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00742391", "title": "A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Actinic Keratoses" ], "interventions": [ { "name": "PEP005 (ingenol mebutate) Gel", "type": "DRUG" }, { "name": "Vehicle gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 255, "start_date": "2008-09", "completion_date": "2009-02", "has_results": true, "last_update_posted_date": "2015-03-06", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 18, "location_summary": "Mesa, Arizona • Denver, Colorado • Kissimmee, Florida + 14 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Denver", "state": "Colorado" }, { "city": "Kissimmee", "state": "Florida" }, { "city": "Orange Park", "state": "Florida" }, { "city": "Ormond Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00742391" }, { "nct_id": "NCT01541553", "title": "A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "Cryotherapy", "type": "PROCEDURE" }, { "name": "Vehicle", "type": "DRUG" }, { "name": "Ingenol metabute", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "LEO Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 367, "start_date": "2012-03", "completion_date": "2013-07", "has_results": true, "last_update_posted_date": "2025-03-10", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 35, "location_summary": "Fremont, California • Oceanside, California • San Diego, California + 30 more", "locations": [ { "city": "Fremont", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01541553" }, { "nct_id": "NCT00432185", "title": "To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Superficial Basal Cell Carcinoma" ], "interventions": [ { "name": "PEP005", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 117, "start_date": "2007-02", "completion_date": "2010-03", "has_results": false, "last_update_posted_date": "2016-02-15", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 9, "location_summary": "Mesa, Arizona • Oceanside, California • San Diego, California + 6 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Oceanside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Clermont", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00432185" }, { "nct_id": "NCT00700063", "title": "A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "PEP005 Topical Gel", "type": "DRUG" }, { "name": "Vehicle gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 265, "start_date": "2008-06", "completion_date": "2008-10", "has_results": true, "last_update_posted_date": "2015-04-14", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 25, "location_summary": "Hot Springs, Arizona • Little Rock, Arkansas • Los Angeles, California + 20 more", "locations": [ { "city": "Hot Springs", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Riverside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00700063" }, { "nct_id": "NCT02124239", "title": "Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "Ingenol mebutate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LEO Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2014-04", "completion_date": "2014-11", "has_results": false, "last_update_posted_date": "2025-02-24", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT02124239" }, { "nct_id": "NCT00942604", "title": "A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Actinic Keratoses" ], "interventions": [ { "name": "PEP005 (ingenol mebutate) Gel", "type": "DRUG" }, { "name": "Vehicle gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 203, "start_date": "2009-07", "completion_date": "2009-10", "has_results": true, "last_update_posted_date": "2015-03-06", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 17, "location_summary": "Hot Springs, Arizona • San Diego, California • Alpharetta, Georgia + 14 more", "locations": [ { "city": "Hot Springs", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Alpharetta", "state": "Georgia" }, { "city": "Arlington Heights", "state": "Illinois" }, { "city": "Buffalo Grove", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00942604" }, { "nct_id": "NCT02748902", "title": "Exploratory Study of Efficacy and Safety of Ingenol Mebutate 0.05% Gel for Common Warts on the Hands.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Verruca Vulgaris", "Common Warts" ], "interventions": [ { "name": "ingenol mebutate 0.05% gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Neal D. Bhatia, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 16, "start_date": "2016-04-27", "completion_date": "2017-03-30", "has_results": false, "last_update_posted_date": "2017-07-17", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02748902" }, { "nct_id": "NCT00544297", "title": "A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Actinic Keratosis" ], "interventions": [ { "name": "PEP005 gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12, "start_date": "2007-10", "completion_date": "2008-01", "has_results": false, "last_update_posted_date": "2015-04-02", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 4, "location_summary": "San Diego, California • Snellville, Georgia • San Antonio, Texas + 1 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Snellville", "state": "Georgia" }, { "city": "San Antonio", "state": "Texas" }, { "city": "Tyler", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00544297" }, { "nct_id": "NCT02411851", "title": "Treatment of Actinic Keratoses (AK) on the Face", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Actinic Keratoses" ], "interventions": [ { "name": "ingenol mebutate 0.015%", "type": "DRUG" }, { "name": "dermasil lotion", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Icahn School of Medicine at Mount Sinai", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2015-03", "completion_date": "2016-06", "has_results": false, "last_update_posted_date": "2017-02-01", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02411851" }, { "nct_id": "NCT00357916", "title": "Study to Determine the Sensitizing Potential of PEP005 Topical Gel in Healthy Volunteers Using a Repeat Insult Patch Test Design", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "PEP005 Topical Gel (0.01% concentration)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peplin", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 200, "start_date": "2006-06", "completion_date": "2006-10", "has_results": false, "last_update_posted_date": "2016-04-05", "last_synced_at": "2026-09-15T03:30:43.625Z", "location_count": 1, "location_summary": "Paramus, New Jersey", "locations": [ { "city": "Paramus", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00357916" } ] }