{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=joint+manipulation&page=2",
    "query": {
      "intervention": "joint manipulation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=joint+manipulation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T23:30:01.085Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02848456",
      "title": "The Effects of Spinal Manipulation on Central Nervous System Activity Measured by Reflexive Calf Muscle Recruitment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subluxation of Joint of Lumbar Spine"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Max Voluntary Isometric Contraction",
          "type": "PROCEDURE"
        },
        {
          "name": "SM+MVIC",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Grant Sanders",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "20 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2014-08",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2017-04-19",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02848456"
    },
    {
      "nct_id": "NCT02036905",
      "title": "Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Cervical and thoracic mobilization",
          "type": "OTHER"
        },
        {
          "name": "cervical and thoracic manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Youngstown State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2013-07",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-01-26",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 2,
      "location_summary": "Solon, Ohio • Havertown, Pennsylvania",
      "locations": [
        {
          "city": "Solon",
          "state": "Ohio"
        },
        {
          "city": "Havertown",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02036905"
    },
    {
      "nct_id": "NCT01406847",
      "title": "Central Mechanisms of Intervention for Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Spinal Mobilization",
          "type": "OTHER"
        },
        {
          "name": "Static Touch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 159,
      "start_date": "2012-08",
      "completion_date": "2017-05-01",
      "has_results": false,
      "last_update_posted_date": "2018-04-05",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01406847"
    },
    {
      "nct_id": "NCT02344485",
      "title": "Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Constipation"
      ],
      "interventions": [
        {
          "name": "OMM treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2015-01-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-13",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02344485"
    },
    {
      "nct_id": "NCT04234282",
      "title": "Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Knee Arthritis",
        "Knee Pain Chronic",
        "Knee Deformity",
        "Knee Pain Swelling",
        "Muscle Weakness",
        "Muscle Weakness Condition",
        "Power"
      ],
      "interventions": [
        {
          "name": "Manual Physical Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jennifer Moreno Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "45 Years to 74 Years"
      },
      "enrollment_count": 40,
      "start_date": "2020-01",
      "completion_date": "2020-07",
      "has_results": false,
      "last_update_posted_date": "2020-01-21",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04234282"
    },
    {
      "nct_id": "NCT03157349",
      "title": "Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Pain",
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Biofreeze",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sport and Spine Rehab Clinical Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 59,
      "start_date": "2017-03-01",
      "completion_date": "2019-02-01",
      "has_results": false,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Landover, Maryland",
      "locations": [
        {
          "city": "Landover",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03157349"
    },
    {
      "nct_id": "NCT03379168",
      "title": "Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Microfragmented Adipose Tissue (Lipogems)",
          "type": "DEVICE"
        },
        {
          "name": "Corticosteroid injection",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Dustin L. Richter, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2018-04-01",
      "completion_date": "2023-10-01",
      "has_results": true,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03379168"
    },
    {
      "nct_id": "NCT04972929",
      "title": "Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Sham Spinal Manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2023-09-15",
      "completion_date": "2025-03-12",
      "has_results": true,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04972929"
    },
    {
      "nct_id": "NCT02727049",
      "title": "Motion Capture and Analysis of NYIT Athletes",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Athletic Injuries"
      ],
      "interventions": [
        {
          "name": "Osteopathic manipulative medicine (OMM)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-02",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2017-10-12",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 2,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        },
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02727049"
    },
    {
      "nct_id": "NCT07385677",
      "title": "Comparing the Effectiveness of the 'Think in Nerve Length and Layers' (TINLL) Approach to Traditional Treatment for Patients With Lateral Elbow Pain.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lateral Elbow Tendinopathy (Tennis Elbow)"
      ],
      "interventions": [
        {
          "name": "TINLL techniques for relieving radial nerve tension",
          "type": "OTHER"
        },
        {
          "name": "Traditional techniques to stretch and strengthen muscles",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2024-11-26",
      "completion_date": "2026-11-26",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-09-22T23:30:01.085Z",
      "location_count": 1,
      "location_summary": "South Burlington, Vermont",
      "locations": [
        {
          "city": "South Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07385677"
    }
  ]
}