{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=labetalol", "query": { "intervention": "labetalol" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 42, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=labetalol&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-01T23:30:05.915Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00293735", "title": "Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Preeclampsia", "Pregnancy Induced Hypertension", "Gestational Hypertension", "Chronic Hypertension", "Superimposed Preeclampsia" ], "interventions": [ { "name": "labetalol (seizure prevention)", "type": "DRUG" }, { "name": "MgSO4 (seizure prevention)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "15 Years to 60 Years · Female only" }, "enrollment_count": 0, "start_date": "2015-06", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-01-13", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00293735" }, { "nct_id": "NCT00848991", "title": "Comparison of Propofol to Precedex With Propofol for Emergence and Recovery in Patients Having Craniotomy Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cranitomy Surgery" ], "interventions": [ { "name": "Precedex", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cooper Health System", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 15, "start_date": "2009-02", "completion_date": "2010-02", "has_results": false, "last_update_posted_date": "2012-02-10", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "Camden, New Jersey", "locations": [ { "city": "Camden", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00848991" }, { "nct_id": "NCT00194974", "title": "Treatment Targets for Chronic Hypertension in Pregnancy", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Pregnancy Toxemia", "Hypertension", "Proteinuria" ], "interventions": [ { "name": "methyldopa", "type": "DRUG" }, { "name": "labetalol", "type": "DRUG" }, { "name": "nifedipine", "type": "DRUG" }, { "name": "clonidine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "FEMALE", "summary": "18 Years to 50 Years · Female only" }, "enrollment_count": 0, "start_date": "2004-07", "completion_date": "2005-03", "has_results": false, "last_update_posted_date": "2017-01-30", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00194974" }, { "nct_id": "NCT07746271", "title": "Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension in Pregnancy", "Obstetrical Complications" ], "interventions": [ { "name": "Anti-hypertensive medication titrated to a BP goal of <140/90 mmHg", "type": "DRUG" }, { "name": "Usual Care: Anti-hypertensive medication for BP ≥160/110 mmHg titrated to a goal of < 160/110 mmHg", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "The George Washington University Biostatistics Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": "56 Years", "sex": "FEMALE", "summary": "14 Years to 56 Years · Female only" }, "enrollment_count": 4120, "start_date": "2026-08-15", "completion_date": "2030-04-30", "has_results": false, "last_update_posted_date": "2026-08-05", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 14, "location_summary": "Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Francisco", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "New York", "state": "New York" }, { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07746271" }, { "nct_id": "NCT03511118", "title": "Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lactating Women on Select DOI", "Breastfed Infants of Mothers on Select DOI" ], "interventions": [ { "name": "Tranexamic acid (TXA)", "type": "DRUG" }, { "name": "labetalol", "type": "DRUG" }, { "name": "metformin", "type": "DRUG" }, { "name": "nifedipine", "type": "DRUG" }, { "name": "clindamycin", "type": "DRUG" }, { "name": "oxycodone", "type": "DRUG" }, { "name": "azithromycin", "type": "DRUG" }, { "name": "escitalopram", "type": "DRUG" }, { "name": "sertraline", "type": "DRUG" }, { "name": "ondansetron", "type": "DRUG" }, { "name": "Ciprofloxacin", "type": "DRUG" }, { "name": "Doxycycline", "type": "DRUG" }, { "name": "Levofloxacin", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" }, { "name": "Sumatriptan", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Cyclobenzaprine", "type": "DRUG" }, { "name": "Furosemide", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Hydroxyurea", "type": "DRUG" }, { "name": "Rosuvastatin", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Trazodone", "type": "DRUG" }, { "name": "Valganciclovir", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Verapamil", "type": "DRUG" }, { "name": "Remdesivir", "type": "DRUG" }, { "name": "Anakinra", "type": "DRUG" }, { "name": "Tocilizumab", "type": "DRUG" }, { "name": "Fluvoxamine", "type": "DRUG" }, { "name": "Amoxicillin", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Hydrocodone", "type": "DRUG" }, { "name": "Levetiracetam", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Buprenorphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1600, "start_date": "2018-10-04", "completion_date": "2028-07-31", "has_results": false, "last_update_posted_date": "2026-07-29", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 20, "location_summary": "La Jolla, California • Loma Linda, California • Chicago, Illinois + 15 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03511118" }, { "nct_id": "NCT00000297", "title": "Effects of Labetalol on Nicotine Administration in Humans - 14", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Tobacco Use Disorder" ], "interventions": [ { "name": "Labetalol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Drug Abuse (NIDA)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "21 Years to 55 Years" }, "enrollment_count": 0, "start_date": "1998-10", "completion_date": "2001-12", "has_results": false, "last_update_posted_date": "2017-01-12", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000297" }, { "nct_id": "NCT03506724", "title": "Response to Anti-hypertensives in Pregnant and Postpartum Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension in Pregnancy", "Preeclampsia" ], "interventions": [ { "name": "Nifedipine", "type": "DRUG" }, { "name": "Labetalol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Icahn School of Medicine at Mount Sinai", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "FEMALE", "summary": "18 Years to 55 Years · Female only" }, "enrollment_count": 109, "start_date": "2017-09-11", "completion_date": "2019-04-05", "has_results": true, "last_update_posted_date": "2021-05-24", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 2, "location_summary": "Brooklyn, New York • New York, New York", "locations": [ { "city": "Brooklyn", "state": "New York" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03506724" }, { "nct_id": "NCT03661346", "title": "Esmolol vs. Labetalol in Endoscopic Sinus Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Sinusitis" ], "interventions": [ { "name": "Labetalol", "type": "DRUG" }, { "name": "Esmolol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Medical Branch, Galveston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2017-03-01", "completion_date": "2018-03-30", "has_results": true, "last_update_posted_date": "2021-02-08", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "Galveston, Texas", "locations": [ { "city": "Galveston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03661346" }, { "nct_id": "NCT04755764", "title": "Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Systolic Hypertension", "Pregnancy Related", "Diastolic Hypertension", "Cardiac Output, Low", "Cardiac Output, High" ], "interventions": [ { "name": "Labetalol", "type": "DRUG" }, { "name": "Atenolol", "type": "DRUG" }, { "name": "Nifedipine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Marshall University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "18 Years to 45 Years · Female only" }, "enrollment_count": 60, "start_date": "2021-03-03", "completion_date": "2025-12", "has_results": false, "last_update_posted_date": "2025-05-13", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "Huntington, West Virginia", "locations": [ { "city": "Huntington", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04755764" }, { "nct_id": "NCT01248169", "title": "Impedance Cardiographic (ICG) Assessment of Pregnant Women With Severe Hypertension to Assess Impact of Standard Therapy", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pregnancy; Proteinuria, With Hypertension (Severe Pre-eclampsia)", "Delivery; Proteinuria, With Gestational Hypertension (Pre-eclampsia, Severe)", "Pregnancy; Hypertension, Gestational Hypertension, With Albuminuria (Severe Pre-eclampsia)" ], "interventions": [], "intervention_types": [], "sponsor": "University of Mississippi Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "18 Years to 45 Years · Female only" }, "enrollment_count": 30, "start_date": "2009-12", "completion_date": "2013-11", "has_results": false, "last_update_posted_date": "2013-12-12", "last_synced_at": "2026-09-01T23:30:05.915Z", "location_count": 1, "location_summary": "Jackson, Mississippi", "locations": [ { "city": "Jackson", "state": "Mississippi" } ], "official_url": "https://clinicaltrials.gov/study/NCT01248169" } ] }