{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=leukocyte+esterase+test",
    "query": {
      "intervention": "leukocyte esterase test"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-14T19:35:31.481Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04390607",
      "title": "Leukocyte Esterase Sensor Test",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "leukocyte esterase electrochemical assay",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 230,
      "start_date": "2020-11-01",
      "completion_date": "2021-10-31",
      "has_results": false,
      "last_update_posted_date": "2020-09-23",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04390607"
    },
    {
      "nct_id": "NCT07784829",
      "title": "Rapid UTI Diagnostics in Lower Urinary Tract Dysfunction Among Catheter Users",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurogenic Bladder Disorder",
        "Lower Urinary Tract Disorder",
        "Urinary Tract Infection (Diagnosis)"
      ],
      "interventions": [
        {
          "name": "urine Resazurin Reduction Ratio",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "USQNB",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-09",
      "completion_date": "2029-07",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07784829"
    },
    {
      "nct_id": "NCT06951009",
      "title": "Establishing Baseline Sysmex UF-5000 Flow Cytometer Results in Healthy Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urethritis",
        "Healthy Men Age 18-50 With no Urethral Symptoms"
      ],
      "interventions": [
        {
          "name": "Colli-Pee",
          "type": "DEVICE"
        },
        {
          "name": "standard of care 60 mL urine cup",
          "type": "DEVICE"
        },
        {
          "name": "Urinalysis",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sysmex UP-5000",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 20,
      "start_date": "2025-04-09",
      "completion_date": "2025-05-07",
      "has_results": true,
      "last_update_posted_date": "2026-08-17",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06951009"
    },
    {
      "nct_id": "NCT03704766",
      "title": "Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Joint Infection",
        "Infection of Hip Joint (Disorder)",
        "Infection of Shoulder Joint",
        "Septic Arthritis"
      ],
      "interventions": [
        {
          "name": "Synovial Alpha-defensin assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Neutrophil elastase assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial lactate assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Staphylococcus spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Candida spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Enterococcus faecalis assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial bacterial culture by BacT/Alert",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Gram Stain",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Leukocyte Esterase Test Strips",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial PCR for Kingella kingae",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum erythrocyte sedimentation rate (ESR)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum D-dimer",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Procalcitonin",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Cultures",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Optional blood testing per standard of care (ASO, anti-strep, ANA, anti-DS-DNA, HLA-B27, RF, Lyme and other inflammatory/ rheumatologic markers )",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 442,
      "start_date": "2016-06-28",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • New York, New York • Collierville, Tennessee",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Collierville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03704766"
    },
    {
      "nct_id": "NCT04614870",
      "title": "DETEC® Esterase for Screening Wound Infection at Point of Care",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Venous Leg Ulcer",
        "Pressure Ulcer"
      ],
      "interventions": [
        {
          "name": "DETEC® Esterase",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Progenitec Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2022-05-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 1,
      "location_summary": "Arlington, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04614870"
    },
    {
      "nct_id": "NCT05440032",
      "title": "LE as a Marker for Periprosthetic Joint Infection",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prosthetic-joint Infection"
      ],
      "interventions": [
        {
          "name": "Semi-quantitative electrochemical leukocyte esterse test strip",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Roche Chemstrip",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Center for Innovation and Research Organization",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2023-12-07",
      "completion_date": "2024-03",
      "has_results": false,
      "last_update_posted_date": "2024-01-30",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 8,
      "location_summary": "Denver, Colorado • Weston, Florida • Louisville, Kentucky + 5 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Weston",
          "state": "Florida"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05440032"
    },
    {
      "nct_id": "NCT02032732",
      "title": "Utilization of Leukocyte Esterase in the Diagnosis of Pediatric Joint Infections",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Joint Infection",
        "Septic Arthritis"
      ],
      "interventions": [
        {
          "name": "leukocyte esterase test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Months to 18 Years"
      },
      "enrollment_count": 9,
      "start_date": "2013-12",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2018-11-29",
      "last_synced_at": "2026-09-14T19:35:31.481Z",
      "location_count": 1,
      "location_summary": "Chattanooga, Tennessee",
      "locations": [
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02032732"
    }
  ]
}