{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=levodopa&page=11", "query": { "intervention": "levodopa", "page": 11 }, "page_size": 10 }, "pagination": { "page": 11, "page_size": 10, "total_count": 253, "total_pages": 26, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=levodopa&page=12&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=levodopa&page=10&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-27T15:53:03.495Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00456794", "title": "12-Week, Double-Blind, Placebo-Controlled Study of 20 and 60 mg/Day Istradefylline in Parkinson's Disease Patients on Levodopa/Carbodopa", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "Istradefylline (KW-6002)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyowa Kirin, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 325, "start_date": "2002-03", "completion_date": "2003-10", "has_results": false, "last_update_posted_date": "2024-04-25", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 1, "location_summary": "Princeton, New Jersey", "locations": [ { "city": "Princeton", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00456794" }, { "nct_id": "NCT00024622", "title": "PET Scanning in Parkinson s Disease", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Schizophrenia", "Parkinson's Disease" ], "interventions": [ { "name": "O-15 Water", "type": "DRUG" }, { "name": "18F-Fluoro-L-dopa", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 502, "start_date": "2002-03-15", "completion_date": null, "has_results": false, "last_update_posted_date": "2026-10-27", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00024622" }, { "nct_id": "NCT00634556", "title": "Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Tourette Syndrome" ], "interventions": [ { "name": "levodopa solution 2mg/ml for i.v. use", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 49, "start_date": "2006-02", "completion_date": "2010-10", "has_results": false, "last_update_posted_date": "2018-02-12", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00634556" }, { "nct_id": "NCT02453386", "title": "Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Idiopathic Parkinson's Disease" ], "interventions": [ { "name": "tozadenant", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biotie Therapies Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "30 Years to 80 Years" }, "enrollment_count": 449, "start_date": "2015-07", "completion_date": "2018-01-12", "has_results": true, "last_update_posted_date": "2019-04-03", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 40, "location_summary": "Birmingham, Alabama • Sun City, Arizona • Loma Linda, California + 37 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Loma Linda", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Oxnard", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02453386" }, { "nct_id": "NCT00660673", "title": "Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Advanced Parkinson's Disease" ], "interventions": [ { "name": "Levodopa-Carbidopa Intestinal Gel (LCIG)", "type": "DRUG" }, { "name": "CADD-Legacy® 1400 ambulatory infusion pump", "type": "DEVICE" }, { "name": "Percutaneous Endoscopic Gastrostomy with jejunal extension tube (PEG-J)", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "99 Years", "sex": null, "summary": "30 Years to 99 Years" }, "enrollment_count": 262, "start_date": "2009-11-13", "completion_date": "2021-11-30", "has_results": true, "last_update_posted_date": "2022-12-02", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 31, "location_summary": "Birmingham, Alabama • Encinitas, California • Fountain Valley, California + 25 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Encinitas", "state": "California" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Englewood", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00660673" }, { "nct_id": "NCT04000919", "title": "Effects of 5HTP and LDOPA on CNS Excitability After SCI", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "5HTP", "type": "DRUG" }, { "name": "L-DOPA", "type": "DRUG" }, { "name": "Placebo oral tablet", "type": "DRUG" }, { "name": "Carbidopa", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jessica M D'Amico", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 30, "start_date": "2019-06-19", "completion_date": "2023-12-30", "has_results": false, "last_update_posted_date": "2022-10-17", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 1, "location_summary": "Louisville, Kentucky", "locations": [ { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT04000919" }, { "nct_id": "NCT01770145", "title": "Apokyn for Motor IMProvement of Morning AKinesia Trial (AM IMPAKT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Parkinson's Disease", "Motor Symptoms", "Akinesia", "Hypomobility", "Delayed Levodopa Onset" ], "interventions": [ { "name": "APOKYN", "type": "DRUG" }, { "name": "L-dopa", "type": "DRUG" }, { "name": "Trimethobenzamide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 127, "start_date": "2012-12", "completion_date": "2014-04", "has_results": true, "last_update_posted_date": "2023-08-14", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 12, "location_summary": "Los Angeles, California • Reseda, California • Washington D.C., District of Columbia + 9 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Reseda", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01770145" }, { "nct_id": "NCT01491529", "title": "Evaluation of the Efficacy and Safety of Modified Release AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dyskinesias", "Parkinson Disease", "Movement Disorders", "Parkinsonian Disorders", "Anti-Dyskinesia Agents" ], "interventions": [ { "name": "AFQ056", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "30 Years to 80 Years" }, "enrollment_count": 154, "start_date": "2012-04", "completion_date": "2013-04", "has_results": false, "last_update_posted_date": "2020-12-23", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 5, "location_summary": "Sunnyvale, California • Englewood, Colorado • Tampa, Florida + 2 more", "locations": [ { "city": "Sunnyvale", "state": "California" }, { "city": "Englewood", "state": "Colorado" }, { "city": "Tampa", "state": "Florida" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01491529" }, { "nct_id": "NCT02605434", "title": "A Study to Assess the Safety and Efficacy of the of the Gastric-retentive AP-CD/LD in Advanced Parkinson's Patients", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "Accordion Pill™ Carbidopa/Levodopa", "type": "DRUG" }, { "name": "Sinemet®", "type": "DRUG" }, { "name": "Placebo -AP-CD/LD", "type": "DRUG" }, { "name": "Placebo- Sinemet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Intec Pharma Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 420, "start_date": "2016-03", "completion_date": "2019-12", "has_results": false, "last_update_posted_date": "2019-08-08", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 36, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Fountain Valley, California + 32 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02605434" }, { "nct_id": "NCT00001849", "title": "New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cushing Syndrome", "Endocrine Disease" ], "interventions": [ { "name": "Pentetreotide", "type": "DRUG" }, { "name": "18F-DOPA", "type": "DRUG" }, { "name": "CT scan", "type": "DEVICE" }, { "name": "MRI", "type": "DEVICE" }, { "name": "18-FDG", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 95, "start_date": "1999-05-20", "completion_date": "2019-04-26", "has_results": true, "last_update_posted_date": "2021-04-14", "last_synced_at": "2026-10-27T15:53:03.495Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001849" } ] }