{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lidocaine%2C+epinephrine+%28Local+anesthetic%29&page=2",
    "query": {
      "intervention": "lidocaine, epinephrine (Local anesthetic)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 81,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lidocaine%2C+epinephrine+%28Local+anesthetic%29&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lidocaine%2C+epinephrine+%28Local+anesthetic%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T21:15:13.946Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03913845",
      "title": "The Impact of Retropubic Lidocaine vs Saline on Postoperative Urinary Retention Following Midurethral Sling",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Stress Urinary Incontinence"
      ],
      "interventions": [
        {
          "name": "lidocaine with epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Normal saline with epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "West Penn Allegheny Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 99 Years · Female only"
      },
      "enrollment_count": 150,
      "start_date": "2019-11-25",
      "completion_date": "2024-11-14",
      "has_results": true,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 4,
      "location_summary": "Bethel Park, Pennsylvania • Jefferson Hills, Pennsylvania • Pittsburgh, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Bethel Park",
          "state": "Pennsylvania"
        },
        {
          "city": "Jefferson Hills",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Wexford",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03913845"
    },
    {
      "nct_id": "NCT01796808",
      "title": "Fat Grafting for Pedal Fat Pad Atrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pedal Fat Pad Atrophy"
      ],
      "interventions": [
        {
          "name": "Pedal Fat Grafting",
          "type": "PROCEDURE"
        },
        {
          "name": "Local anesthetic",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2013-03",
      "completion_date": "2017-04",
      "has_results": false,
      "last_update_posted_date": "2018-02-14",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01796808"
    },
    {
      "nct_id": "NCT06057675",
      "title": "Tranexamic Acid in Nasal Mohs Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Bleeding",
        "Skin Cancer Face"
      ],
      "interventions": [
        {
          "name": "Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine)",
          "type": "DRUG"
        },
        {
          "name": "Control (1% lidocaine with 1:100,000 epinephrine)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2024-03-19",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06057675"
    },
    {
      "nct_id": "NCT01622049",
      "title": "Selective Laser Photocoagulation of Communicating Vessels in Twin-Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Selective Laser Photocoagulation of Communicating Vessels",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 77,
      "start_date": "2006-10",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2013-03-14",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01622049"
    },
    {
      "nct_id": "NCT05300685",
      "title": "Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Urethral Stricture, Male"
      ],
      "interventions": [
        {
          "name": "Standard Buccal Harvest",
          "type": "DRUG"
        },
        {
          "name": "Basic buccal procedure + Long acting local",
          "type": "DRUG"
        },
        {
          "name": "Basic buccal procedure + Buccal block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 60,
      "start_date": "2022-02-15",
      "completion_date": "2026-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05300685"
    },
    {
      "nct_id": "NCT00583011",
      "title": "Local Anesthesia and Pain Perception During an Amniocentesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Local Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "Placebo Group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 76,
      "start_date": "2007-10",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2021-02-03",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00583011"
    },
    {
      "nct_id": "NCT04880707",
      "title": "Twin Block, Pain Medications and Third Molar Extractions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "Twin block local anesthetic nerve block using standard dental anesthetic",
          "type": "DRUG"
        },
        {
          "name": "Twin block with placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2024-03-11",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04880707"
    },
    {
      "nct_id": "NCT05294640",
      "title": "Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Eyelid Tumor",
        "Eyelid Bump",
        "Eyelid Deformity",
        "Eyelid Abscess",
        "Eyelid Boil",
        "Eyelid Papilloma",
        "Anesthesia, Local",
        "Ophthalmology"
      ],
      "interventions": [
        {
          "name": "0.9% Bacteriostatic Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "Eyelid Lesion Removal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 95,
      "start_date": "2022-05-17",
      "completion_date": "2023-02-21",
      "has_results": true,
      "last_update_posted_date": "2025-07-08",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05294640"
    },
    {
      "nct_id": "NCT00889642",
      "title": "Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Local Anesthesia"
      ],
      "interventions": [
        {
          "name": "Iontophoretic Drug Delivery System with Lidocaine/Epinephrine",
          "type": "DEVICE"
        },
        {
          "name": "Iontophoretic Drug Delivery System with Epinephrine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dharma Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2009-05",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2009-06-23",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 2,
      "location_summary": "Anaheim, California • Overland Park, Missouri",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Overland Park",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00889642"
    },
    {
      "nct_id": "NCT07527039",
      "title": "Pectoral Block in Breast Reduction for Pain Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Macromastia (Symptomatic)"
      ],
      "interventions": [
        {
          "name": "Pectoral II Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Post Operative Pain Relievers",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 80,
      "start_date": "2026-04-01",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-10-10T21:15:13.946Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07527039"
    }
  ]
}