{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=light&page=4",
    "query": {
      "intervention": "light",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 2795,
    "total_pages": 280,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=light&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=light&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T03:04:25.281Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07090226",
      "title": "Diffuse Cutaneous Scleroderma (DSSc) SFDI Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Systemic Scleroderma",
        "Diffuse Cutaneous Scleroderma"
      ],
      "interventions": [
        {
          "name": "Spatial-frequency domain imaging (SFDI)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2025-11-06",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07090226"
    },
    {
      "nct_id": "NCT07753889",
      "title": "Relationships Among Pupil Responses to Light, Circadian Rhythms, and Sleep",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Circadian Rhythm",
        "Pupillometry",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Ocular light exposure from portable light box",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Elizabeth B Klerman MD PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 100,
      "start_date": "2027-09-01",
      "completion_date": "2035-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-08",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07753889"
    },
    {
      "nct_id": "NCT02658708",
      "title": "Bright Light on Fatigue in Women Being Treated for Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Breast Neoplasms",
        "Breast Cancer",
        "Cancer of Breast",
        "Cancer of the Breast"
      ],
      "interventions": [
        {
          "name": "Bright blue-green light using light visor cap",
          "type": "OTHER"
        },
        {
          "name": "Dim red light using light visor cap",
          "type": "OTHER"
        },
        {
          "name": "European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Epworth Sleepiness Scale",
          "type": "OTHER"
        },
        {
          "name": "Pittsburgh Sleep Quality Index",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue",
          "type": "OTHER"
        },
        {
          "name": "Digital foot candle datalogging light meter (Extech Instrument, Model SDL400)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Polysomnography (Easy Ambulatory 2 Cadwell, Kennewick, WA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Horne-Ostberg Morningness-Eveningness Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Daily Fatigue and Sleep Log",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 19,
      "start_date": "2015-10-12",
      "completion_date": "2017-05-09",
      "has_results": false,
      "last_update_posted_date": "2017-09-25",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02658708"
    },
    {
      "nct_id": "NCT00096278",
      "title": "Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II or Stage III Colon Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Colon Adenocarcinoma",
        "Stage IIA Colon Cancer AJCC v7",
        "Stage IIB Colon Cancer AJCC v7",
        "Stage IIC Colon Cancer AJCC v7",
        "Stage IIIA Colon Cancer AJCC v7",
        "Stage IIIB Colon Cancer AJCC v7",
        "Stage IIIC Colon Cancer AJCC v7"
      ],
      "interventions": [
        {
          "name": "Bevacizumab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fluorouracil",
          "type": "DRUG"
        },
        {
          "name": "Leucovorin Calcium",
          "type": "DRUG"
        },
        {
          "name": "Oxaliplatin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2710,
      "start_date": "2004-09-15",
      "completion_date": "2012-12-31",
      "has_results": true,
      "last_update_posted_date": "2019-07-30",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00096278"
    },
    {
      "nct_id": "NCT01324908",
      "title": "Biomarkers in Predicting Response in Patients With Graft-Versus-Host Disease Undergoing Extracorporeal Photophoresis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Graft Versus Host Disease (GVHD)"
      ],
      "interventions": [
        {
          "name": "extracorporeal photopheresis",
          "type": "PROCEDURE"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Vanderbilt-Ingram Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2011-07",
      "completion_date": "2020-11-16",
      "has_results": false,
      "last_update_posted_date": "2021-01-14",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 4,
      "location_summary": "Atlanta, Georgia • Boston, Massachusetts • Nashville, Tennessee + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01324908"
    },
    {
      "nct_id": "NCT05219955",
      "title": "Caregiver Stress and Sleep Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depressive Symptoms",
        "Caregiver Burden"
      ],
      "interventions": [
        {
          "name": "Morning Action Plan Execution",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Activity Strategy-based Session with Therapist",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention-based Session with Therapist",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Advance sleep-wake time",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2022-07-15",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05219955"
    },
    {
      "nct_id": "NCT01500135",
      "title": "Comparison of Efficacy and Safety of TachoSil® Versus Surgicel® Original for the Secondary Hemostatic Treatment of Needle Hole Bleeding in Vascular Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bleeding"
      ],
      "interventions": [
        {
          "name": "TachoSil®",
          "type": "DRUG"
        },
        {
          "name": "Surgicel® Original",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2012-03",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2017-02-08",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 37,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Long Beach, California + 25 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01500135"
    },
    {
      "nct_id": "NCT03095235",
      "title": "Dietary Riboflavin (Vitamin B-2) and Cornea Cross-Linking",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keratoconus",
        "Cornea Ectasia"
      ],
      "interventions": [
        {
          "name": "Dietary riboflavin",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-05-01",
      "completion_date": "2021-03-08",
      "has_results": false,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03095235"
    },
    {
      "nct_id": "NCT07179003",
      "title": "A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Abscess"
      ],
      "interventions": [
        {
          "name": "Standard of care breast abscess drainage",
          "type": "PROCEDURE"
        },
        {
          "name": "Methylene Blue",
          "type": "DRUG"
        },
        {
          "name": "Lipid Emulsion",
          "type": "DRUG"
        },
        {
          "name": "Insertion of optical fiber",
          "type": "DEVICE"
        },
        {
          "name": "Laser illumination",
          "type": "DEVICE"
        },
        {
          "name": "Photodynamic therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2027-07",
      "completion_date": "2032-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07179003"
    },
    {
      "nct_id": "NCT06079853",
      "title": "Nurse Suicide: Physiologic Sleep Health Promotion Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Suicide",
        "Nurse's Role",
        "Work Environment Adverse Effects",
        "Sleep",
        "Stress",
        "Mental Health Wellness 1"
      ],
      "interventions": [
        {
          "name": "PureSomni Sleep Health Product Kit",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2023-09-08",
      "completion_date": "2024-09-01",
      "has_results": true,
      "last_update_posted_date": "2024-11-25",
      "last_synced_at": "2026-10-20T03:04:25.281Z",
      "location_count": 1,
      "location_summary": "Cortlandt Manor, New York",
      "locations": [
        {
          "city": "Cortlandt Manor",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06079853"
    }
  ]
}