{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A",
    "query": {
      "intervention": "lotrafilcon A"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T20:06:57.457Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05976750",
      "title": "Air Optix® Night and Day® Aqua Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors",
        "Myopia",
        "Hyperopia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2023-10-03",
      "completion_date": "2024-07-30",
      "has_results": false,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05976750"
    },
    {
      "nct_id": "NCT06098339",
      "title": "Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Hyperopia"
      ],
      "interventions": [
        {
          "name": "Lens A (fanfilcon A)",
          "type": "DEVICE"
        },
        {
          "name": "Lens B (lotrafilcon B)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 53,
      "start_date": "2023-11-13",
      "completion_date": "2024-04-04",
      "has_results": true,
      "last_update_posted_date": "2024-08-28",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 2,
      "location_summary": "Ocoee, Florida • State College, Pennsylvania",
      "locations": [
        {
          "city": "Ocoee",
          "state": "Florida"
        },
        {
          "city": "State College",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06098339"
    },
    {
      "nct_id": "NCT05827224",
      "title": "Air Optix Daily Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B spherical soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 312,
      "start_date": "2023-08-02",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2024-08-15",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 5,
      "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05827224"
    },
    {
      "nct_id": "NCT01254747",
      "title": "Clinical Evaluation of an Investigational Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Delefilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX)",
          "type": "DEVICE"
        },
        {
          "name": "Nelfilcon A contact lens (DAILIES AquaComfort Plus)",
          "type": "DEVICE"
        },
        {
          "name": "Narafilcon A contact lens (1-DAY ACUVUE TRUEYE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIBA VISION",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2010-11",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2012-07-10",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 1,
      "location_summary": "Duluth, Georgia",
      "locations": [
        {
          "city": "Duluth",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01254747"
    },
    {
      "nct_id": "NCT01952665",
      "title": "A Multi-Center Study Comparing the Clinical Performance of Two Silicone Hydrogel Lenses Over 1 Month of Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "comfilcon A",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 63,
      "start_date": "2013-10",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2017-06-26",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 6,
      "location_summary": "Campbell, California • Whittier, California • Athens, Georgia + 3 more",
      "locations": [
        {
          "city": "Campbell",
          "state": "California"
        },
        {
          "city": "Whittier",
          "state": "California"
        },
        {
          "city": "Athens",
          "state": "Georgia"
        },
        {
          "city": "Oak Lawn",
          "state": "Illinois"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01952665"
    },
    {
      "nct_id": "NCT05992675",
      "title": "Air Optix® Night and Day® Aqua Continuous Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1256,
      "start_date": "2023-10-05",
      "completion_date": "2024-08-22",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05992675"
    },
    {
      "nct_id": "NCT05790928",
      "title": "Air Optix Night and Day Aqua (AONDA) Retrospective Study 1",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Ametropia",
        "Hyperopia",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A spherical contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 108,
      "start_date": "2023-03-25",
      "completion_date": "2023-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 4,
      "location_summary": "Tallahassee, Florida • Franklin Park, Illinois • Eden Prairie, Minnesota + 1 more",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        },
        {
          "city": "Franklin Park",
          "state": "Illinois"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05790928"
    },
    {
      "nct_id": "NCT01094743",
      "title": "Dispensing Evaluation of a Prototype Contact Lens and a Marketed Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "galyfilcon A prototype lens",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 52,
      "start_date": "2010-02-01",
      "completion_date": "2010-03-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Salem, Virginia",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01094743"
    },
    {
      "nct_id": "NCT00937105",
      "title": "Daily Wear Corneal Infiltrative Event Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Hyperopia",
        "Corneal Infiltrative Events"
      ],
      "interventions": [
        {
          "name": "lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Renu Multiplus",
          "type": "DEVICE"
        },
        {
          "name": "Clear Care",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 218,
      "start_date": "2009-11",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2014-03-10",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00937105"
    },
    {
      "nct_id": "NCT05886881",
      "title": "Air Optix Extended Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B spherical soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 505,
      "start_date": "2023-08-03",
      "completion_date": "2025-04-15",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-09-21T20:06:57.457Z",
      "location_count": 4,
      "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05886881"
    }
  ]
}