{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A+contact+lenses", "query": { "intervention": "lotrafilcon A contact lenses" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 32, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A+contact+lenses&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-07T23:34:51.057Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05886881", "title": "Air Optix Extended Wear Contact Lenses", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Refractive Errors" ], "interventions": [ { "name": "Lotrafilcon B spherical soft contact lenses", "type": "DEVICE" }, { "name": "Lotrafilcon B spherical soft contact lenses with comfort additive", "type": "DEVICE" }, { "name": "Lotrafilcon B toric soft contact lenses with comfort additive", "type": "DEVICE" }, { "name": "Comfilcon A spherical soft contact lenses", "type": "DEVICE" }, { "name": "Comfilcon A toric soft contact lenses", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 505, "start_date": "2023-08-03", "completion_date": "2025-04-15", "has_results": false, "last_update_posted_date": "2025-08-14", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 4, "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 1 more", "locations": [ { "city": "Orlando", "state": "Florida" }, { "city": "Medina", "state": "Minnesota" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT05886881" }, { "nct_id": "NCT01254747", "title": "Clinical Evaluation of an Investigational Soft Contact Lens", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia" ], "interventions": [ { "name": "Delefilcon A contact lens", "type": "DEVICE" }, { "name": "Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX)", "type": "DEVICE" }, { "name": "Nelfilcon A contact lens (DAILIES AquaComfort Plus)", "type": "DEVICE" }, { "name": "Narafilcon A contact lens (1-DAY ACUVUE TRUEYE)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "CIBA VISION", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 130, "start_date": "2010-11", "completion_date": "2010-12", "has_results": true, "last_update_posted_date": "2012-07-10", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 1, "location_summary": "Duluth, Georgia", "locations": [ { "city": "Duluth", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01254747" }, { "nct_id": "NCT01699750", "title": "Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia", "Astigmatism", "Refractive Error" ], "interventions": [ { "name": "Lotrafilcon B contact lenses", "type": "DEVICE" }, { "name": "Senofilcon A contact lenses", "type": "DEVICE" }, { "name": "OPTI-FREE® PUREMOIST® MPDS", "type": "DEVICE" }, { "name": "BIOTRUE®", "type": "DEVICE" }, { "name": "Balafilcon A contact lenses", "type": "DEVICE" }, { "name": "ReNu® Multiplus®", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 109, "start_date": "2012-12", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2014-12-08", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01699750" }, { "nct_id": "NCT01244516", "title": "Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia" ], "interventions": [ { "name": "galyfilcon A, BC 8.30", "type": "DEVICE" }, { "name": "lotrafilcon B, BC 8.60", "type": "DEVICE" }, { "name": "comfilcon A, BC 8.60", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johnson & Johnson Vision Care, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "39 Years", "sex": "ALL", "summary": "18 Years to 39 Years" }, "enrollment_count": 540, "start_date": "2010-09-01", "completion_date": "2010-11-01", "has_results": true, "last_update_posted_date": "2018-06-19", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 35, "location_summary": "Brea, California • Campbell, California • Cupertino, California + 31 more", "locations": [ { "city": "Brea", "state": "California" }, { "city": "Campbell", "state": "California" }, { "city": "Cupertino", "state": "California" }, { "city": "Mission Viejo", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01244516" }, { "nct_id": "NCT05338333", "title": "Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Presbyopia" ], "interventions": [ { "name": "Lehfilcon A multifocal contact lenses", "type": "DEVICE" }, { "name": "Lotrafilcon B multifocal contact lenses", "type": "DEVICE" }, { "name": "CLEAR CARE®", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 101, "start_date": "2022-05-27", "completion_date": "2022-09-01", "has_results": true, "last_update_posted_date": "2023-09-13", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 8, "location_summary": "Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more", "locations": [ { "city": "Maitland", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Pittsburg", "state": "Kansas" }, { "city": "Eden Prairie", "state": "Minnesota" }, { "city": "Medina", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05338333" }, { "nct_id": "NCT01526902", "title": "Proclear 1-D Multifocal Nondispensing Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Presbyopia" ], "interventions": [ { "name": "omafilcon A / PC 1-D MF", "type": "DEVICE" }, { "name": "lotrafilcon B / Air Optix MF", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "CooperVision, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "40 Years to 65 Years" }, "enrollment_count": 49, "start_date": "2012-02", "completion_date": "2012-05", "has_results": true, "last_update_posted_date": "2014-04-07", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 1, "location_summary": "Bloomington, Indiana", "locations": [ { "city": "Bloomington", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01526902" }, { "nct_id": "NCT02708524", "title": "Clinical Study of Approved and Investigational Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Visual Acuity" ], "interventions": [ { "name": "Senofilcon C Contact Lens", "type": "DEVICE" }, { "name": "Comfilcon A Contact Lens", "type": "DEVICE" }, { "name": "Lotrafilcon B Contact Lens", "type": "DEVICE" }, { "name": "Samfilcon A Contact Lens", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johnson & Johnson Vision Care, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 554, "start_date": "2016-01", "completion_date": "2016-03", "has_results": true, "last_update_posted_date": "2016-11-09", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 18, "location_summary": "Montgomery, Alabama • Fruit Cove, Florida • Jacksonville, Florida + 14 more", "locations": [ { "city": "Montgomery", "state": "Alabama" }, { "city": "Fruit Cove", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Longwood", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02708524" }, { "nct_id": "NCT00975585", "title": "Clinical Performance Comparison of Two Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia" ], "interventions": [ { "name": "senofilcon A", "type": "DEVICE" }, { "name": "lotrafilcon B", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johnson & Johnson Vision Care, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 379, "start_date": "2009-08-01", "completion_date": "2009-10-01", "has_results": true, "last_update_posted_date": "2018-06-19", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 25, "location_summary": "North Little Rock, Arkansas • Campbell, California • Colorado Springs, Colorado + 21 more", "locations": [ { "city": "North Little Rock", "state": "Arkansas" }, { "city": "Campbell", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00975585" }, { "nct_id": "NCT05805345", "title": "Clinical Comparison of Toric Contact Lenses Fit Characteristics", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Astigmatism", "Refractive Errors" ], "interventions": [ { "name": "Delefilcon A toric soft contact lens", "type": "DEVICE" }, { "name": "Lehfilcon A toric soft contact lens", "type": "DEVICE" }, { "name": "Lotrafilcon B toric soft contact lens", "type": "DEVICE" }, { "name": "Verofilcon A toric soft contact lens", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2023-04", "completion_date": "2023-05", "has_results": false, "last_update_posted_date": "2023-05-19", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 7, "location_summary": "Los Angeles, California • Longwood, Florida • Maitland, Florida + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Longwood", "state": "Florida" }, { "city": "Maitland", "state": "Florida" }, { "city": "Pittsburg", "state": "Kansas" }, { "city": "Granville", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05805345" }, { "nct_id": "NCT01094743", "title": "Dispensing Evaluation of a Prototype Contact Lens and a Marketed Contact Lens", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia" ], "interventions": [ { "name": "galyfilcon A prototype lens", "type": "DEVICE" }, { "name": "lotrafilcon B lens", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johnson & Johnson Vision Care, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "39 Years", "sex": "ALL", "summary": "18 Years to 39 Years" }, "enrollment_count": 52, "start_date": "2010-02-01", "completion_date": "2010-03-01", "has_results": true, "last_update_posted_date": "2018-06-19", "last_synced_at": "2026-10-07T23:34:51.057Z", "location_count": 2, "location_summary": "Jacksonville, Florida • Salem, Virginia", "locations": [ { "city": "Jacksonville", "state": "Florida" }, { "city": "Salem", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01094743" } ] }