{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A+contact+lenses&page=2",
    "query": {
      "intervention": "lotrafilcon A contact lenses",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 32,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A+contact+lenses&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+A+contact+lenses&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-11T07:34:57.501Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01254747",
      "title": "Clinical Evaluation of an Investigational Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Delefilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX)",
          "type": "DEVICE"
        },
        {
          "name": "Nelfilcon A contact lens (DAILIES AquaComfort Plus)",
          "type": "DEVICE"
        },
        {
          "name": "Narafilcon A contact lens (1-DAY ACUVUE TRUEYE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIBA VISION",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2010-11",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2012-07-10",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 1,
      "location_summary": "Duluth, Georgia",
      "locations": [
        {
          "city": "Duluth",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01254747"
    },
    {
      "nct_id": "NCT05338333",
      "title": "Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 101,
      "start_date": "2022-05-27",
      "completion_date": "2022-09-01",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 8,
      "location_summary": "Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05338333"
    },
    {
      "nct_id": "NCT01526902",
      "title": "Proclear 1-D Multifocal Nondispensing Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "omafilcon A / PC 1-D MF",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B / Air Optix MF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 49,
      "start_date": "2012-02",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2014-04-07",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01526902"
    },
    {
      "nct_id": "NCT01423773",
      "title": "Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ocular Comfort"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A test contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon A control contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Ultra-High Resolution Optical Coherence Tomographer (OCT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIBA VISION",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2011-08",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2013-06-28",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01423773"
    },
    {
      "nct_id": "NCT03026257",
      "title": "Clinical Assessment of a HYDRAGLYDE® Regimen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Myopia",
        "Hypermetropia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B contact lenses with added wetting agent",
          "type": "DEVICE"
        },
        {
          "name": "Samfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent",
          "type": "DEVICE"
        },
        {
          "name": "Hydrogen peroxide-based contact lens solution with added wetting agent",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon C contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Habitual Multi-Purpose Solution (HMPS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon, a Novartis Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 323,
      "start_date": "2017-02-13",
      "completion_date": "2017-08-18",
      "has_results": true,
      "last_update_posted_date": "2018-08-14",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 5,
      "location_summary": "Birmingham, Alabama • Cleveland, Ohio • Columbus, Ohio + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03026257"
    },
    {
      "nct_id": "NCT01763047",
      "title": "Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "etafilcon A",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 298,
      "start_date": "2012-11",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 19,
      "location_summary": "Mission Viejo, California • Jacksonville, Florida • Saint Augustine, Florida + 15 more",
      "locations": [
        {
          "city": "Mission Viejo",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Saint Augustine",
          "state": "Florida"
        },
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01763047"
    },
    {
      "nct_id": "NCT05886881",
      "title": "Air Optix Extended Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B spherical soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 505,
      "start_date": "2023-08-03",
      "completion_date": "2025-04-15",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 4,
      "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05886881"
    },
    {
      "nct_id": "NCT02328937",
      "title": "Central Corneal Swelling With Silicone Hydrogel Materials",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Swelling"
      ],
      "interventions": [
        {
          "name": "etafilcon A",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B",
          "type": "DEVICE"
        },
        {
          "name": "comfilcon A",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 41,
      "start_date": "2014-11",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02328937"
    },
    {
      "nct_id": "NCT00727402",
      "title": "Longitudinal Evaluation of Silicone Hydrogel (LASH) Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Corneal Infiltrates"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 205,
      "start_date": "2006-10",
      "completion_date": "2009-10",
      "has_results": true,
      "last_update_posted_date": "2012-02-15",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00727402"
    },
    {
      "nct_id": "NCT05956535",
      "title": "Air Optix® Night and Day® Aqua Therapeutic Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bullous Keratopathy",
        "Corneal Erosion",
        "Entropion",
        "Corneal Edema",
        "Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2023-09-26",
      "completion_date": "2024-10-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-13",
      "last_synced_at": "2026-10-11T07:34:57.501Z",
      "location_count": 3,
      "location_summary": "Delray Beach, Florida • St Louis, Missouri • Fort Worth, Texas",
      "locations": [
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05956535"
    }
  ]
}