{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+B",
    "query": {
      "intervention": "lotrafilcon B"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=lotrafilcon+B&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-17T22:08:45.990Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05827224",
      "title": "Air Optix Daily Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B spherical soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 312,
      "start_date": "2023-08-02",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2024-08-15",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 5,
      "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05827224"
    },
    {
      "nct_id": "NCT03881670",
      "title": "On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hyperopia",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B with Hydraluxe",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 24,
      "start_date": "2018-12-07",
      "completion_date": "2019-02-08",
      "has_results": true,
      "last_update_posted_date": "2020-03-10",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03881670"
    },
    {
      "nct_id": "NCT05886894",
      "title": "Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B multifocal soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A multifocal soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 351,
      "start_date": "2023-08-08",
      "completion_date": "2025-06-20",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05886894"
    },
    {
      "nct_id": "NCT05886881",
      "title": "Air Optix Extended Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B spherical soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 505,
      "start_date": "2023-08-03",
      "completion_date": "2025-04-15",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 4,
      "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05886881"
    },
    {
      "nct_id": "NCT01151371",
      "title": "Clinical Evaluation Of Two Daily Disposable Contact Lenses And A Monthly Replacement Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "narafilcon B contact lens",
          "type": "DEVICE"
        },
        {
          "name": "nelfilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 452,
      "start_date": "2010-02-01",
      "completion_date": "2010-04-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 28,
      "location_summary": "Brea, California • Canoga Park, California • Corona, California + 23 more",
      "locations": [
        {
          "city": "Brea",
          "state": "California"
        },
        {
          "city": "Canoga Park",
          "state": "California"
        },
        {
          "city": "Corona",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01151371"
    },
    {
      "nct_id": "NCT01094743",
      "title": "Dispensing Evaluation of a Prototype Contact Lens and a Marketed Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "galyfilcon A prototype lens",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 52,
      "start_date": "2010-02-01",
      "completion_date": "2010-03-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Salem, Virginia",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01094743"
    },
    {
      "nct_id": "NCT06098339",
      "title": "Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Hyperopia"
      ],
      "interventions": [
        {
          "name": "Lens A (fanfilcon A)",
          "type": "DEVICE"
        },
        {
          "name": "Lens B (lotrafilcon B)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 53,
      "start_date": "2023-11-13",
      "completion_date": "2024-04-04",
      "has_results": true,
      "last_update_posted_date": "2024-08-28",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 2,
      "location_summary": "Ocoee, Florida • State College, Pennsylvania",
      "locations": [
        {
          "city": "Ocoee",
          "state": "Florida"
        },
        {
          "city": "State College",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06098339"
    },
    {
      "nct_id": "NCT00975585",
      "title": "Clinical Performance Comparison of Two Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "senofilcon A",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 379,
      "start_date": "2009-08-01",
      "completion_date": "2009-10-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 25,
      "location_summary": "North Little Rock, Arkansas • Campbell, California • Colorado Springs, Colorado + 21 more",
      "locations": [
        {
          "city": "North Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Campbell",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00975585"
    },
    {
      "nct_id": "NCT03118934",
      "title": "Assessing Fitting Guides in Alcon Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia",
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Nelfilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Delefilcon A multifocal contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 188,
      "start_date": "2017-05-17",
      "completion_date": "2017-07-28",
      "has_results": true,
      "last_update_posted_date": "2018-09-26",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 14,
      "location_summary": "Phoenix, Arizona • San Diego, California • Pensacola, Florida + 10 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Pensacola",
          "state": "Florida"
        },
        {
          "city": "Tallahassee",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03118934"
    },
    {
      "nct_id": "NCT01244516",
      "title": "Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "galyfilcon A, BC 8.30",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B, BC 8.60",
          "type": "DEVICE"
        },
        {
          "name": "comfilcon A, BC 8.60",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 540,
      "start_date": "2010-09-01",
      "completion_date": "2010-11-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-09-17T22:08:45.990Z",
      "location_count": 35,
      "location_summary": "Brea, California • Campbell, California • Cupertino, California + 31 more",
      "locations": [
        {
          "city": "Brea",
          "state": "California"
        },
        {
          "city": "Campbell",
          "state": "California"
        },
        {
          "city": "Cupertino",
          "state": "California"
        },
        {
          "city": "Mission Viejo",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01244516"
    }
  ]
}