{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=low-calorie+diet&page=4",
    "query": {
      "intervention": "low-calorie diet",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 392,
    "total_pages": 40,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=low-calorie+diet&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=low-calorie+diet&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T18:27:37.668Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00079547",
      "title": "The Safety and Effectiveness of Low and High Carbohydrate Diets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Low-calorie diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "low-carbohydrate diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Temple University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 307,
      "start_date": "2003-04",
      "completion_date": "2008-03",
      "has_results": false,
      "last_update_posted_date": "2013-07-01",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00079547"
    },
    {
      "nct_id": "NCT02244411",
      "title": "Exercise and QUality Diet After Leukemia: The EQUAL Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adult Survivors of Childhood Leukemia"
      ],
      "interventions": [
        {
          "name": "individual diet & physical activity counselor and website through Healthways at Hopkins",
          "type": "BEHAVIORAL"
        },
        {
          "name": "self directed weight loss",
          "type": "BEHAVIORAL"
        },
        {
          "name": "questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "fasting blood draw, measurement of height, weight and waist circumference, and blood pressure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 358,
      "start_date": "2014-09",
      "completion_date": "2025-07-16",
      "has_results": true,
      "last_update_posted_date": "2026-07-24",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 2,
      "location_summary": "New York, New York • Memphis, Tennessee",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02244411"
    },
    {
      "nct_id": "NCT02301416",
      "title": "Qsymia as an Adjunct to Surgical Therapy in the Superobese",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obesity",
        "Metabolic Surgery",
        "Weight Loss",
        "Bariatric Surgery Procedures"
      ],
      "interventions": [
        {
          "name": "Phentermine/topiramate",
          "type": "DRUG"
        },
        {
          "name": "low calorie diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 25,
      "start_date": "2014-12",
      "completion_date": "2018-06-27",
      "has_results": true,
      "last_update_posted_date": "2019-09-04",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02301416"
    },
    {
      "nct_id": "NCT07651800",
      "title": "Energy Deficiency on Hormones in Contraceptive Users",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Energy Deficiency Due to Short-term Fasting",
        "Hormonal Contraception"
      ],
      "interventions": [
        {
          "name": "Energy Deficiency of approximately ~250 kcal/day",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2026-09",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07651800"
    },
    {
      "nct_id": "NCT04186793",
      "title": "Comparison of Dietary Sugar Reduction Methods",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nonalcoholic Fatty Liver Disease"
      ],
      "interventions": [
        {
          "name": "Guided Grocery Shopping (GGS)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Diet Provision Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "8 Years to 16 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-02-06",
      "completion_date": "2021-12-15",
      "has_results": false,
      "last_update_posted_date": "2022-03-25",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04186793"
    },
    {
      "nct_id": "NCT06363747",
      "title": "The Medically Reproducing Bariatric Surgery (MRB) II Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Very Low Calorie Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Durham VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-06-24",
      "completion_date": "2025-11-03",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "Greenville, North Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06363747"
    },
    {
      "nct_id": "NCT02068885",
      "title": "Framingham State Food Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Diabetes",
        "Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Feeding study",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 234,
      "start_date": "2014-08-17",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "Framingham, Massachusetts",
      "locations": [
        {
          "city": "Framingham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02068885"
    },
    {
      "nct_id": "NCT05235425",
      "title": "The Lifestyle Education About Prediabetes (Leap) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PreDiabetes"
      ],
      "interventions": [
        {
          "name": "Standard NDPP",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Very low-carbohydrate diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 304,
      "start_date": "2022-03-20",
      "completion_date": "2025-11-14",
      "has_results": false,
      "last_update_posted_date": "2026-10-06",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05235425"
    },
    {
      "nct_id": "NCT04026776",
      "title": "Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Salt; Excess",
        "Blood Pressure Disorders"
      ],
      "interventions": [
        {
          "name": "Allopurinol",
          "type": "DRUG"
        },
        {
          "name": "Dietary Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "33 Years",
        "sex": "ALL",
        "summary": "22 Years to 33 Years"
      },
      "enrollment_count": 120,
      "start_date": "2020-09-02",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04026776"
    },
    {
      "nct_id": "NCT00472680",
      "title": "The Effect of Severe Weight Loss and Protein Intake on Bone",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Caloric restriction, high protein",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Caloric restriction; normal protein",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nutrition Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2010-03",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2022-02-01",
      "last_synced_at": "2026-10-07T18:27:37.668Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00472680"
    }
  ]
}