{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=mannitol&page=4", "query": { "intervention": "mannitol", "page": 4 }, "page_size": 10 }, "pagination": { "page": 4, "page_size": 10, "total_count": 150, "total_pages": 15, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=mannitol&page=5&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=mannitol&page=3&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-18T18:33:38.727Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00947882", "title": "A Trial of Degarelix in Men With Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lower Urinary Tract Symptoms (LUTS)" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Degarelix 10 mg", "type": "DRUG" }, { "name": "Degarelix 20 mg", "type": "DRUG" }, { "name": "Degarelix 30 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ferring Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "MALE", "summary": "50 Years and older · Male only" }, "enrollment_count": 404, "start_date": "2009-08", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2015-06-08", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 15, "location_summary": "Homewood, Alabama • Mobile, Alabama • Newport Beach, California + 12 more", "locations": [ { "city": "Homewood", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Newport Beach", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Englewood", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00947882" }, { "nct_id": "NCT03895749", "title": "Effect of a Nitric Oxide Supplementation Product on Endothelial Dysfunction and Prehypertensive Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "NEO40 Daily", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Hypertension Institute, Nashville", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 42, "start_date": "2017-04-05", "completion_date": "2018-04-18", "has_results": false, "last_update_posted_date": "2019-10-30", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03895749" }, { "nct_id": "NCT00439244", "title": "Efficacy Study of Zoledronic Acid and Teriparatide Combination Therapy in Women With Osteoporosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Osteoporosis" ], "interventions": [ { "name": "Zoledronic acid", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Teriparatide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "89 Years", "sex": "FEMALE", "summary": "45 Years to 89 Years · Female only" }, "enrollment_count": 412, "start_date": "2006-12", "completion_date": "2009-02", "has_results": true, "last_update_posted_date": "2011-04-20", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 18, "location_summary": "Birmingham, Alabama • Beverly Hills, California • La Mesa, California + 15 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Beverly Hills", "state": "California" }, { "city": "La Mesa", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00439244" }, { "nct_id": "NCT02563561", "title": "A Study of Intravesical Apaziquone as a Surgical Adjuvant in Participant Undergoing Transurethral Resection Bladder Tumor (TURBT)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bladder Cancer" ], "interventions": [ { "name": "Apaziquone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Spectrum Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2015-10-09", "completion_date": "2017-03-10", "has_results": true, "last_update_posted_date": "2021-10-27", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT02563561" }, { "nct_id": "NCT05555290", "title": "PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "PT027", "type": "COMBINATION_PRODUCT" }, { "name": "PT007", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "130 Years", "sex": "ALL", "summary": "18 Years to 130 Years" }, "enrollment_count": 190, "start_date": "2022-09-28", "completion_date": "2024-11-18", "has_results": true, "last_update_posted_date": "2026-01-27", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 1, "location_summary": "Columbia, Maryland", "locations": [ { "city": "Columbia", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05555290" }, { "nct_id": "NCT02306473", "title": "The Leaky Lung Test", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Asthma", "Allergy", "Reactive Airway Disease", "Lung Diseases, Obstructive" ], "interventions": [ { "name": "Mannitol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 100, "start_date": "2015-10", "completion_date": "2017-12-01", "has_results": false, "last_update_posted_date": "2018-01-04", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02306473" }, { "nct_id": "NCT01220128", "title": "Evaluation of an Anti-cancer Immunotherapy Combined With Standard Neoadjuvant Treatment in Patients With WT1-positive Primary Invasive Breast Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Neoplasms, Breast" ], "interventions": [ { "name": "GSK Biologicals' recombinant WT1 Antigen-Specific Cancer Immunotherapeutic (ASCI) GSK2302024A", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Aromatase inhibitor", "type": "DRUG" }, { "name": "5-Fluorouracil", "type": "DRUG" }, { "name": "Carboplatin AUC", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Docetaxel", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Epirubicin", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Trastuzumab", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 66, "start_date": "2011-04-11", "completion_date": "2014-11-14", "has_results": true, "last_update_posted_date": "2021-05-25", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 8, "location_summary": "Newark, Delaware • Plantation, Florida • Boston, Massachusetts + 5 more", "locations": [ { "city": "Newark", "state": "Delaware" }, { "city": "Plantation", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Bend", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01220128" }, { "nct_id": "NCT01215019", "title": "Osmotic Therapy for Treatment of Intracranial Hypertension for Traumatic Brain Injury", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Traumatic Brain Injury" ], "interventions": [ { "name": "Mannitol", "type": "DRUG" }, { "name": "NaCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2010-10", "completion_date": "2020-10", "has_results": false, "last_update_posted_date": "2013-04-04", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01215019" }, { "nct_id": "NCT00042367", "title": "Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants With Brain Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Brain Tumors" ], "interventions": [ { "name": "Induction therapy (Regimen 1, Course 1, Cycle A1", "type": "DRUG" }, { "name": "Regimen 1, Course 1, Cycle A2 (Days 22 - 42)", "type": "DRUG" }, { "name": "Cycle B", "type": "DRUG" }, { "name": "Regimen 1, Course 2", "type": "DRUG" }, { "name": "Intrathecal Mafosfamide", "type": "DRUG" }, { "name": "Regimen 1 Course 2, IT mafosfamide", "type": "DRUG" }, { "name": "Regimen 2, Course 1", "type": "DRUG" }, { "name": "Regimen 2, Course, 1, Cycle C1", "type": "DRUG" }, { "name": "Regimen 2, Course 2", "type": "DRUG" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "36 Months", "sex": "ALL", "summary": "Up to 36 Months" }, "enrollment_count": 119, "start_date": "2000-04-04", "completion_date": "2006-06", "has_results": false, "last_update_posted_date": "2020-03-04", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 3, "location_summary": "Durham, North Carolina • Memphis, Tennessee • Houston, Texas", "locations": [ { "city": "Durham", "state": "North Carolina" }, { "city": "Memphis", "state": "Tennessee" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00042367" }, { "nct_id": "NCT01258634", "title": "A Study of Pre-Operative Treatment of Newly-Diagnosed, Surgically-Resectable Osteosarcoma With Doxorubicin, Ifosfamide, Etoposide, and Cisplatin With Early Metabolic Assessment of Response", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Osteosarcoma", "Lung Metastases" ], "interventions": [ { "name": "Dexrazoxane", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "G-CSF", "type": "DRUG" }, { "name": "PEG-filgrastim", "type": "DRUG" }, { "name": "Etoposide", "type": "DRUG" }, { "name": "Ifosfamide", "type": "DRUG" }, { "name": "Mesna", "type": "DRUG" }, { "name": "Leucovorin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "2 Years to 35 Years" }, "enrollment_count": 2, "start_date": "2010-07", "completion_date": "2011-11", "has_results": false, "last_update_posted_date": "2013-12-10", "last_synced_at": "2026-10-18T18:33:38.727Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01258634" } ] }