{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=manual+lymphatic+drainage&page=2",
    "query": {
      "intervention": "manual lymphatic drainage",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=manual+lymphatic+drainage&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=manual+lymphatic+drainage&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-03T22:55:26.600Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05890677",
      "title": "The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema, Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Surgical Intervention",
          "type": "PROCEDURE"
        },
        {
          "name": "Conservative Complex Physical Decongestion Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University Hospital, Basel, Switzerland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 280,
      "start_date": "2023-07-14",
      "completion_date": "2036-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 4,
      "location_summary": "New Haven, Connecticut • Boston, Massachusetts • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05890677"
    },
    {
      "nct_id": "NCT06589115",
      "title": "Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Plateau Fractures"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction Cuff",
          "type": "OTHER"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-12-01",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06589115"
    },
    {
      "nct_id": "NCT03760744",
      "title": "Imaging Biomarkers of Lymphatic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Secondary Lymphedema"
      ],
      "interventions": [
        {
          "name": "CDT with Negative Pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "CDT alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "90 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 90 Years · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2019-01-23",
      "completion_date": "2025-03-15",
      "has_results": true,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03760744"
    },
    {
      "nct_id": "NCT05946837",
      "title": "Near-infrared Fluorescence Lymphatic Imaging Assessment of Lymphatic Response to Pneumatic Back/Neck Lymphatic Drainage Delivered by a Pneumatic Manual Lymphatic Drainage Device",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Neck Pain",
        "Back Pain"
      ],
      "interventions": [
        {
          "name": "Indocyanine green (ICG) dye",
          "type": "DRUG"
        },
        {
          "name": "NIRF-LI imaging",
          "type": "DEVICE"
        },
        {
          "name": "Neuroglide pad",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2023-08-29",
      "completion_date": "2023-09-01",
      "has_results": false,
      "last_update_posted_date": "2023-12-14",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05946837"
    },
    {
      "nct_id": "NCT03292198",
      "title": "Subclinical Lymphedema Treatment Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer-related Subclinical Lymphedema"
      ],
      "interventions": [
        {
          "name": "20-30 mmHg compression sleeve and gauntlet",
          "type": "OTHER"
        },
        {
          "name": "Manual Lymphatic Drainage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mercy Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 267,
      "start_date": "2018-04-01",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03292198"
    },
    {
      "nct_id": "NCT01019512",
      "title": "Flexitouch Lymphedema System in Treating Stage II Lymphedema in Patients With Breast Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Lymphedema"
      ],
      "interventions": [
        {
          "name": "questionnaire administration",
          "type": "OTHER"
        },
        {
          "name": "lymphedema management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 60,
      "start_date": "2009-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-03-25",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01019512"
    },
    {
      "nct_id": "NCT04045860",
      "title": "Complete Decongestive Therapy on Head and Neck Lymphedema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema of Face",
        "Secondary Lymphedema"
      ],
      "interventions": [
        {
          "name": "Complete Decongestive Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Observation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Our Lady of the Lake Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2019-01-24",
      "completion_date": "2021-06-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-08",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04045860"
    },
    {
      "nct_id": "NCT02591056",
      "title": "Study of the Combined Effect of Low Level Laser Therapy and Manual Lymph Drainage on Reducing Body Circumference",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Circumference Reduction"
      ],
      "interventions": [
        {
          "name": "Erchonia® Verju™ Laser",
          "type": "DEVICE"
        },
        {
          "name": "Green PRESS 8",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Erchonia Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2016-01",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2020-02-10",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 3,
      "location_summary": "Stockton, California • Marion, Indiana • Bloomfield Hills, Michigan",
      "locations": [
        {
          "city": "Stockton",
          "state": "California"
        },
        {
          "city": "Marion",
          "state": "Indiana"
        },
        {
          "city": "Bloomfield Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02591056"
    },
    {
      "nct_id": "NCT00058851",
      "title": "Massage Therapy for Breast Cancer Treatment-Related Swelling of the Arms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lymphedema"
      ],
      "interventions": [
        {
          "name": "Manual lymph drainage",
          "type": "PROCEDURE"
        },
        {
          "name": "Combined physiotherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Compression bandaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 88,
      "start_date": "2003-01",
      "completion_date": "2007-11",
      "has_results": false,
      "last_update_posted_date": "2009-08-19",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00058851"
    },
    {
      "nct_id": "NCT00383500",
      "title": "Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Flexitouch",
          "type": "DEVICE"
        },
        {
          "name": "Class 1 compression garment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2005-05",
      "completion_date": "2009-09",
      "has_results": true,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-10-03T22:55:26.600Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00383500"
    }
  ]
}