{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=manual+therapy+and+exercise&page=2",
    "query": {
      "intervention": "manual therapy and exercise",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 253,
    "total_pages": 26,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=manual+therapy+and+exercise&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=manual+therapy+and+exercise&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T06:38:58.610Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02261740",
      "title": "Program to Overcome Pelvic Pain With Yoga",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Pain"
      ],
      "interventions": [
        {
          "name": "Yoga Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 16,
      "start_date": "2014-10",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-10-04",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02261740"
    },
    {
      "nct_id": "NCT04851730",
      "title": "The Effect of an Individualized Impairment-based, Orthopedic Physical Therapy Intervention (IOI), on Muscle Stiffness, Pelvic Floor Function, and Pain in Women With Chronic Pelvic Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Pain",
        "Chronic Pain",
        "Muscle Tightness"
      ],
      "interventions": [
        {
          "name": "Orthopedic Physical Therapy Intervention",
          "type": "PROCEDURE"
        },
        {
          "name": "Dry Needling",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Texas Woman's University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 15,
      "start_date": "2021-04-12",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-04-20",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "Lee's Summit, Missouri",
      "locations": [
        {
          "city": "Lee's Summit",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04851730"
    },
    {
      "nct_id": "NCT01427153",
      "title": "A Comparison of Manual Physical Therapy and Corticosteroid Injections for Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Orthopaedic manual physical therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Corticosteroid Injection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Madigan Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "38 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "38 Years and older"
      },
      "enrollment_count": 156,
      "start_date": "2012-08",
      "completion_date": "2019-05",
      "has_results": false,
      "last_update_posted_date": "2025-01-27",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 2,
      "location_summary": "San Antonio, Texas • Tacoma, Washington",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01427153"
    },
    {
      "nct_id": "NCT05600465",
      "title": "Behavioral Activation + Occupational Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Chronic Conditions",
        "Disability Physical"
      ],
      "interventions": [
        {
          "name": "Behavioral Activation + Occupational Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2022-11-01",
      "completion_date": "2024-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05600465"
    },
    {
      "nct_id": "NCT00494065",
      "title": "Chiropractic and Self-care for Back-Related Leg Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sub-acute and Chronic Back-related Leg Pain"
      ],
      "interventions": [
        {
          "name": "Home exercise",
          "type": "OTHER"
        },
        {
          "name": "Chiropractic Spinal Manipulative Therapy + Home exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern Health Sciences University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 192,
      "start_date": "2007-06",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2014-01-31",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 2,
      "location_summary": "Davenport, Iowa • Bloomington, Minnesota",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        },
        {
          "city": "Bloomington",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00494065"
    },
    {
      "nct_id": "NCT04158219",
      "title": "Healthy Heart Habits",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Acute Coronary Syndrome",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Behavioral activation for health and depression (BA-HD)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hennepin Healthcare Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 8,
      "start_date": "2019-11-15",
      "completion_date": "2021-02-24",
      "has_results": true,
      "last_update_posted_date": "2022-03-10",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04158219"
    },
    {
      "nct_id": "NCT03959319",
      "title": "Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip-related Groin Pain",
        "Femoroacetabular Impingement",
        "Dysplasia Mild",
        "Prearthritic Hip Disorder"
      ],
      "interventions": [
        {
          "name": "Movement Pattern Training",
          "type": "OTHER"
        },
        {
          "name": "Manual Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 33,
      "start_date": "2019-07-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-01-31",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03959319"
    },
    {
      "nct_id": "NCT04036331",
      "title": "Dyad Plus Effectiveness/Feasibility",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight Loss",
        "Pediatric Obesity",
        "Overweight Adolescents",
        "Parent-Child Relations",
        "Family and Household"
      ],
      "interventions": [
        {
          "name": "Brenner FIT Standard",
          "type": "BEHAVIORAL"
        },
        {
          "name": "By Design Essentials",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dyad Plus",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "13 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2021-07-30",
      "completion_date": "2026-04-22",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04036331"
    },
    {
      "nct_id": "NCT03859713",
      "title": "Optimize Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Physical Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Phase I Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Phase II Switching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 749,
      "start_date": "2019-03-22",
      "completion_date": "2024-10-01",
      "has_results": true,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03859713"
    },
    {
      "nct_id": "NCT01900925",
      "title": "Does Prescriptive Treatment of the Hips Improve Outcomes in Patients With Low Back Pain? A Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Prescriptive Hip Exercises and Manual Therapy techniques",
          "type": "PROCEDURE"
        },
        {
          "name": "Pragmatic low back pain treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Regis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2013-09",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2016-05-02",
      "last_synced_at": "2026-10-04T06:38:58.610Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01900925"
    }
  ]
}