{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=metoprolol&page=2", "query": { "intervention": "metoprolol", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=metoprolol&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-29T02:47:53.185Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03556592", "title": "Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Atopic Dermatitis" ], "interventions": [ { "name": "Tralokinumab", "type": "DRUG" }, { "name": "Caffeine", "type": "DRUG" }, { "name": "Warfarin", "type": "DRUG" }, { "name": "Omeprazole", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Midazolam Hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LEO Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2018-08-13", "completion_date": "2020-06-20", "has_results": false, "last_update_posted_date": "2025-02-24", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 9, "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • San Diego, California + 5 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "San Diego", "state": "California" }, { "city": "Doral", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03556592" }, { "nct_id": "NCT00849810", "title": "Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Metoprolol", "type": "DRUG" }, { "name": "Nebivolol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Mississippi Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2009-01", "completion_date": "2010-11", "has_results": true, "last_update_posted_date": "2013-03-19", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 1, "location_summary": "Jackson, Mississippi", "locations": [ { "city": "Jackson", "state": "Mississippi" } ], "official_url": "https://clinicaltrials.gov/study/NCT00849810" }, { "nct_id": "NCT01093703", "title": "Chronotherapy Versus Conventional BP Control to Correct Abnormal Circadian BP Pattern in Kidney Transplant Recipients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Blood Pressure Control", "Kidney Transplant Recipient" ], "interventions": [ { "name": "Medication Adjustment", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 99, "start_date": "2008-12", "completion_date": "2012-11", "has_results": false, "last_update_posted_date": "2013-05-30", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01093703" }, { "nct_id": "NCT00401882", "title": "Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cardiac Arrest", "Sudden Cardiac Death", "Ventricular Fibrillation", "Tachycardia, Ventricular" ], "interventions": [ { "name": "Epinephrine", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "David Haines, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7, "start_date": "2007-01", "completion_date": "2012-03", "has_results": true, "last_update_posted_date": "2017-05-25", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 1, "location_summary": "Royal Oak, Michigan", "locations": [ { "city": "Royal Oak", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00401882" }, { "nct_id": "NCT06783868", "title": "Assessing the Neurological Outcomes After Atrial Fibrillation Ablation for Rhythm Control", "overall_status": "NOT_YET_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Atrial Fibrillation", "Stroke" ], "interventions": [ { "name": "Catheter Ablation", "type": "DEVICE" }, { "name": "Market-approved AVNB, OAC and AAD", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Kansas City Heart Rhythm Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2025-10", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2025-08-28", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 7, "location_summary": "Overland Park, Kansas • Independence, Missouri • Kansas City, Missouri", "locations": [ { "city": "Overland Park", "state": "Kansas" }, { "city": "Overland Park", "state": "Kansas" }, { "city": "Overland Park", "state": "Kansas" }, { "city": "Independence", "state": "Missouri" }, { "city": "Independence", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT06783868" }, { "nct_id": "NCT00993421", "title": "A Weight Loss Study in Overweight Men and Women", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "LY377604", "type": "DRUG" }, { "name": "Sibutramine", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Placebo sibutramine", "type": "DRUG" }, { "name": "Placebo Metoprolol", "type": "DRUG" }, { "name": "Placebo LY377604", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 343, "start_date": "2009-10", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2011-06-03", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 21, "location_summary": "Mesa, Arizona • Concord, California • La Jolla, California + 18 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Concord", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Waterbury", "state": "Connecticut" }, { "city": "South Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00993421" }, { "nct_id": "NCT03138603", "title": "Metoprolol to Reduce Perioperative Myocardial Injury", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Heart Diseases" ], "interventions": [ { "name": "Metoprolol Tartrate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 72, "start_date": "2016-12", "completion_date": "2023-08-29", "has_results": true, "last_update_posted_date": "2026-01-28", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 2, "location_summary": "Chicago, Illinois • St Louis, Missouri", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT03138603" }, { "nct_id": "NCT01441570", "title": "The Impact of Nebivolol Versus Metoprolol on Quality of Life", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Transplant; Failure, Kidney", "Hypertension" ], "interventions": [ { "name": "Nebivolol", "type": "DRUG" }, { "name": "Metoprolol succinate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 11, "start_date": "2012-02", "completion_date": "2013-07", "has_results": true, "last_update_posted_date": "2017-04-20", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Burlington, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Burlington", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01441570" }, { "nct_id": "NCT01501929", "title": "Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Metoprolol succinate", "type": "DRUG" }, { "name": "Nebivolol", "type": "DRUG" }, { "name": "Non-invasive measurement of Cardiac Output (CO)", "type": "PROCEDURE" }, { "name": "Endothelial cell collection", "type": "PROCEDURE" }, { "name": "Microvascular perfusion assessment using Definity", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 32, "start_date": "2010-08", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2018-11-06", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01501929" }, { "nct_id": "NCT00744237", "title": "Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension", "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Nebivolol", "type": "DRUG" }, { "name": "Metoprolol ER", "type": "DRUG" }, { "name": "HCTZ", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 231, "start_date": "2008-08", "completion_date": null, "has_results": true, "last_update_posted_date": "2011-07-29", "last_synced_at": "2026-09-29T02:47:53.185Z", "location_count": 62, "location_summary": "Athens, Alabama • Huntsville, Alabama • Bell Gardens, California + 54 more", "locations": [ { "city": "Athens", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Bell Gardens", "state": "California" }, { "city": "Buena Park", "state": "California" }, { "city": "Chino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00744237" } ] }