{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=nicotine+patch+%2B+nicotine+lozenge&page=3",
    "query": {
      "intervention": "nicotine patch + nicotine lozenge",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 138,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=nicotine+patch+%2B+nicotine+lozenge&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=nicotine+patch+%2B+nicotine+lozenge&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T05:55:17.811Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04694846",
      "title": "Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Non-Small Cell Carcinoma",
        "Head and Neck Squamous Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement",
          "type": "DRUG"
        },
        {
          "name": "Bupropion Hydrochloride Controlled-release",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Tobacco Cessation Counseling",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Quality of Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "Best Practice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2020-08-19",
      "completion_date": "2024-08-16",
      "has_results": false,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04694846"
    },
    {
      "nct_id": "NCT03315910",
      "title": "Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing (MI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Replacement Therapy (NRT)",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Lozenge",
          "type": "DRUG"
        },
        {
          "name": "Message Framing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "saliva sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 807,
      "start_date": "2017-10-10",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 18,
      "location_summary": "Los Angeles, California • Walnut Creek, California • La Grange, Georgia + 14 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "La Grange",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Kankakee",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03315910"
    },
    {
      "nct_id": "NCT01892813",
      "title": "Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Nicotine replacement therapy - Transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - Nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - Nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - Transdermal nicotine patch + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Tobacco quitline referral",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tailored behavioral intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alcohol use risk reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral activation for depressive symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral management of postcessation weight gain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Mark Vander Weg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 411,
      "start_date": "2013-07",
      "completion_date": "2018-01",
      "has_results": false,
      "last_update_posted_date": "2017-07-11",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01892813"
    },
    {
      "nct_id": "NCT05645146",
      "title": "Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Cervical Cancer",
        "High Grade Cervical Dysplasia"
      ],
      "interventions": [
        {
          "name": "Smoking Cessation treatment delivered by Tobacco Free Florida Quitline",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Lozenge",
          "type": "DRUG"
        },
        {
          "name": "Motivation and Problem Solving (MAPS) intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 360,
      "start_date": "2022-11-29",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05645146"
    },
    {
      "nct_id": "NCT02564315",
      "title": "The Long-Term Quitting (Smoking Cessation) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine Mini-Lozenge for 11 Months",
          "type": "DRUG"
        },
        {
          "name": "Preparation Phase Behavioral Reduction Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Phase Recycling Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Phase Control Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Supportive Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Skill Training Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Brief Information",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1154,
      "start_date": "2015-10-30",
      "completion_date": "2019-11-05",
      "has_results": false,
      "last_update_posted_date": "2020-02-17",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02564315"
    },
    {
      "nct_id": "NCT07835555",
      "title": "Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tobacco Use Disorder/Cigarette Smoking",
        "HIV"
      ],
      "interventions": [
        {
          "name": "nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion",
          "type": "DRUG"
        },
        {
          "name": "Multi-target Contingency Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Teamlet booster",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 794,
      "start_date": "2027-09-30",
      "completion_date": "2031-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-23",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 5,
      "location_summary": "Bridgeport, Connecticut • New Haven, Connecticut • Jersey City, New Jersey + 2 more",
      "locations": [
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Jersey City",
          "state": "New Jersey"
        },
        {
          "city": "Paterson",
          "state": "New Jersey"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07835555"
    },
    {
      "nct_id": "NCT06966362",
      "title": "Varenicline for Smoking Reduction in Veterans Not Ready To Quit",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Veterans",
        "Tobacco Use Disorder",
        "Cigarette Smoking",
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Motivation-Phase Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Motivation-Phase Nicotine Mini-Lozenge",
          "type": "DRUG"
        },
        {
          "name": "Cessation-Phase Combination Nicotine Replacement Therapy (NRT)",
          "type": "DRUG"
        },
        {
          "name": "Cessation-Phase Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Motivation-Phase Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation-Phase Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2026-08-17",
      "completion_date": "2030-06-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Minneapolis, Minnesota • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06966362"
    },
    {
      "nct_id": "NCT01932996",
      "title": "Enhancing Smoking Cessation in the Homeless Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cigarette Smoking",
        "Tobacco Smoking",
        "Smoking, Tobacco"
      ],
      "interventions": [
        {
          "name": "nicotine patch plus nicotine gum/lozenge",
          "type": "DRUG"
        },
        {
          "name": "Intensive Alcohol Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 352,
      "start_date": "2015-01",
      "completion_date": "2018-10-31",
      "has_results": true,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01932996"
    },
    {
      "nct_id": "NCT01123967",
      "title": "Offering Proactive Tobacco Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "proactive outreach (PRO)",
          "type": "OTHER"
        },
        {
          "name": "telephone counseling (TC)",
          "type": "OTHER"
        },
        {
          "name": "Nicotine replacement therapy (NRT)",
          "type": "OTHER"
        },
        {
          "name": "Usual care (UC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 2500,
      "start_date": "2011-02",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2015-05-27",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01123967"
    },
    {
      "nct_id": "NCT00715871",
      "title": "Clinical Study of Smoke-Break Liquid Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "Smoke-Break nicotine delivery device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Smoke-Break, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 52,
      "start_date": "2008-02",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2014-11-19",
      "last_synced_at": "2026-10-04T05:55:17.811Z",
      "location_count": 1,
      "location_summary": "West Allis, Wisconsin",
      "locations": [
        {
          "city": "West Allis",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00715871"
    }
  ]
}