{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=non-caloric+sweetener",
    "query": {
      "intervention": "non-caloric sweetener"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=non-caloric+sweetener&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T19:12:49.532Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02252952",
      "title": "The Effect of Sugar Sweetened and Diet Beverages Consumed as Part of a Weight-Maintenance Diet on Fat Storage",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Focus: Understanding the Obesogenic Potential of Sugars and Non-caloric Sweeteners"
      ],
      "interventions": [
        {
          "name": "Beverage Consumption",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rippe Lifestyle Institute",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 99,
      "start_date": "2013-02",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-12-16",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Celebration, Florida",
      "locations": [
        {
          "city": "Celebration",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02252952"
    },
    {
      "nct_id": "NCT01103921",
      "title": "The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Insulin Resistance",
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Glucose",
          "type": "OTHER"
        },
        {
          "name": "Fructose",
          "type": "OTHER"
        },
        {
          "name": "High-Fructose Corn Syrup",
          "type": "OTHER"
        },
        {
          "name": "No sugar (Aspartame)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 214,
      "start_date": "2008-10",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01103921"
    },
    {
      "nct_id": "NCT01350518",
      "title": "Dietary Intervention for Visceral Adiposity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Benefiber",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "TrueLemon",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 50 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2011-02",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2018-08-28",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01350518"
    },
    {
      "nct_id": "NCT02630667",
      "title": "The Acute Effects Fortified Nutritional Supplementation on Childhood Cognition",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Ability, General",
        "Dietary Modification"
      ],
      "interventions": [
        {
          "name": "SLOW Carbohydrate",
          "type": "OTHER"
        },
        {
          "name": "MEDIUM Carbohydrate",
          "type": "OTHER"
        },
        {
          "name": "FAST Carbohydrate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "9 Years to 10 Years"
      },
      "enrollment_count": 113,
      "start_date": "2012-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-12-08",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02630667"
    },
    {
      "nct_id": "NCT07179107",
      "title": "Adequate Hydration and Health Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration",
        "Dehydration (Physiology)",
        "Glucose Abnormalities",
        "Cardiovascular"
      ],
      "interventions": [
        {
          "name": "Baseline - week 1",
          "type": "OTHER"
        },
        {
          "name": "Low Water Intake - week 2",
          "type": "OTHER"
        },
        {
          "name": "Moderate Water Intake - week 3",
          "type": "OTHER"
        },
        {
          "name": "Adequate Water Intake - week 4",
          "type": "OTHER"
        },
        {
          "name": "Washout - week 5",
          "type": "OTHER"
        },
        {
          "name": "Low fluid intake with non caloric sweeteners - Week 6",
          "type": "OTHER"
        },
        {
          "name": "Moderate fluid intake with non caloric sweeteners - Week 7",
          "type": "OTHER"
        },
        {
          "name": "Adequate fluid intake with non caloric sweeteners - Week 8",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 144,
      "start_date": "2025-09-29",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 2,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07179107"
    },
    {
      "nct_id": "NCT07105826",
      "title": "Impact of Prebiotic Sodas on Satiety and Metabolic Responses in Healthy Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Olipop",
        "Poppi",
        "Coca Cola - Classic",
        "Diet Coke"
      ],
      "interventions": [
        {
          "name": "Prebiotic Soda 1",
          "type": "OTHER"
        },
        {
          "name": "Prebiotic Soda 2",
          "type": "OTHER"
        },
        {
          "name": "Diet Soda",
          "type": "OTHER"
        },
        {
          "name": "Regular Coke",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas Christian University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2025-08-04",
      "completion_date": "2026-03-10",
      "has_results": false,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07105826"
    },
    {
      "nct_id": "NCT02548767",
      "title": "Adverse Metabolic Effects of Dietary Sugar",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Disease of Cardiovascular System",
        "Type 2 Diabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "high fructose corn syrup",
          "type": "OTHER"
        },
        {
          "name": "aspartame",
          "type": "OTHER"
        },
        {
          "name": "Energy-balanced diet",
          "type": "OTHER"
        },
        {
          "name": "Ad libitum diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 36,
      "start_date": "2016-02",
      "completion_date": "2020-03-13",
      "has_results": false,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 3,
      "location_summary": "Davis, California • Sacramento, California • Vallejo, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Vallejo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02548767"
    },
    {
      "nct_id": "NCT04567108",
      "title": "Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Body Weight"
      ],
      "interventions": [
        {
          "name": "Maintain usual SSBs",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Substitute to non-SSBs",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Study app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Beverage delivery",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "20 Years to 69 Years"
      },
      "enrollment_count": 461,
      "start_date": "2021-04-22",
      "completion_date": "2026-05-21",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04567108"
    },
    {
      "nct_id": "NCT03944616",
      "title": "Study Of Drinks With Artificial Sweeteners in People With Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Diet Beverage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Water",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 181,
      "start_date": "2019-06-06",
      "completion_date": "2024-03-21",
      "has_results": true,
      "last_update_posted_date": "2025-09-11",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 2,
      "location_summary": "Irvine, California • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03944616"
    },
    {
      "nct_id": "NCT03889522",
      "title": "The Influence of Non-Caloric Artificial Sweeteners on Youth With Type 1 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Bioelectrical Impedance Analysis",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Total Body Dual-energy X-ray Absorptiometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood draw",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 21,
      "start_date": "2019-05-01",
      "completion_date": "2021-02-25",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-09-25T19:12:49.532Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03889522"
    }
  ]
}