{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=non-sugar+sweetener+-+control",
    "query": {
      "intervention": "non-sugar sweetener - control"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=non-sugar+sweetener+-+control&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T05:28:24.923Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06842693",
      "title": "Testing Non-nutritive Sweetener Labels in Chile",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet, Healthy"
      ],
      "interventions": [
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Chilean non-nutritive sweetener label",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Colombian non-nutritive sweetener label",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3916,
      "start_date": "2025-07-14",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06842693"
    },
    {
      "nct_id": "NCT01128829",
      "title": "Sugar-replacement Sweeteners, and Blood Sugar Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Water",
          "type": "OTHER"
        },
        {
          "name": "Sucralose",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "21 Years to 40 Years"
      },
      "enrollment_count": 17,
      "start_date": "2010-05",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2014-12-22",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128829"
    },
    {
      "nct_id": "NCT05967741",
      "title": "The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Platelet Aggregation, Spontaneous",
        "Vascular Thrombosis"
      ],
      "interventions": [
        {
          "name": "Erythritol",
          "type": "OTHER"
        },
        {
          "name": "Aspartame",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 14,
      "start_date": "2023-07-20",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05967741"
    },
    {
      "nct_id": "NCT04567108",
      "title": "Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Body Weight"
      ],
      "interventions": [
        {
          "name": "Maintain usual SSBs",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Substitute to non-SSBs",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Study app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Beverage delivery",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "20 Years to 69 Years"
      },
      "enrollment_count": 461,
      "start_date": "2021-04-22",
      "completion_date": "2026-05-21",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04567108"
    },
    {
      "nct_id": "NCT04381481",
      "title": "Studying the Impact of Product Packaging in a Virtual Store Environment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Childhood"
      ],
      "interventions": [
        {
          "name": "Experimental Drink: Nutrition claim on fruit drinks",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Drink: No nutrition claim",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experimental snack: Text warning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experimental snack: Graphic warning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control snack: barcode label",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 2374,
      "start_date": "2020-05-14",
      "completion_date": "2020-07-24",
      "has_results": true,
      "last_update_posted_date": "2021-06-18",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04381481"
    },
    {
      "nct_id": "NCT07506577",
      "title": "Impact of Saccharin and Acesulfame-Potassium on Glycemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prediabetes"
      ],
      "interventions": [
        {
          "name": "non-sugar sweetener - saccharin",
          "type": "OTHER"
        },
        {
          "name": "non-sugar sweetener - acesulfame potassium",
          "type": "OTHER"
        },
        {
          "name": "non-sugar sweetener - control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2022-07-30",
      "completion_date": "2025-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07506577"
    },
    {
      "nct_id": "NCT07506564",
      "title": "Acute Impact of Non-Sugar Sweeteners (Sucralose and Aspartame)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prediabetes"
      ],
      "interventions": [
        {
          "name": "non-sugar sweeteners - Sucralose",
          "type": "OTHER"
        },
        {
          "name": "non-sugar sweetener - aspartame",
          "type": "OTHER"
        },
        {
          "name": "Non-sugar sweetener - control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2022-08-01",
      "completion_date": "2025-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07506564"
    },
    {
      "nct_id": "NCT03241706",
      "title": "Liver Glycogen and Hypoglycemia in Humans",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoglycemia; Iatrogenic"
      ],
      "interventions": [
        {
          "name": "Low Fructose",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Somatostatin",
          "type": "DRUG"
        },
        {
          "name": "Insulin",
          "type": "DRUG"
        },
        {
          "name": "Glucagon",
          "type": "DRUG"
        },
        {
          "name": "Dextrose solution",
          "type": "DRUG"
        },
        {
          "name": "High Fructose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jason Winnick",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "21 Years to 40 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-08-02",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-25",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241706"
    },
    {
      "nct_id": "NCT06548828",
      "title": "Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gestational Diabetes Mellitus in Pregnancy",
        "Glucose Intolerance During Pregnancy",
        "Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation"
      ],
      "interventions": [
        {
          "name": "NNS Restriction Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 324,
      "start_date": "2024-08-19",
      "completion_date": "2029-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06548828"
    },
    {
      "nct_id": "NCT07249008",
      "title": "NSS Grocery Store Brazil",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Control Group",
        "Mexico-based NSS FOPL",
        "Brazil-based NSS FOPL"
      ],
      "interventions": [
        {
          "name": "Experimental : Mexico-based NSS FOPL",
          "type": "OTHER"
        },
        {
          "name": "Experimental : Brazil-based NSS FOPL",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 1068,
      "start_date": "2026-02-15",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-25T05:28:24.923Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07249008"
    }
  ]
}