{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=normal+saline+%280.9%25%29",
    "query": {
      "intervention": "normal saline (0.9%)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 1127,
    "total_pages": 113,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=normal+saline+%280.9%25%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T14:47:03.127Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00262470",
      "title": "Treatment of Orthostatic Intolerance",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Tachycardia",
        "Chronic Orthostatic Intolerance"
      ],
      "interventions": [
        {
          "name": "Acetazolamide",
          "type": "DRUG"
        },
        {
          "name": "Atomoxetine",
          "type": "DRUG"
        },
        {
          "name": "NO Drug",
          "type": "OTHER"
        },
        {
          "name": "Clonidine",
          "type": "DRUG"
        },
        {
          "name": "Entacapone",
          "type": "DRUG"
        },
        {
          "name": "Entacapone & Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Atomoxetine & Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Indomethacin",
          "type": "DRUG"
        },
        {
          "name": "Mecamylamine",
          "type": "DRUG"
        },
        {
          "name": "Isosorbide Dinitrate",
          "type": "DRUG"
        },
        {
          "name": "Melatonin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Midodrine",
          "type": "DRUG"
        },
        {
          "name": "Modafinil",
          "type": "DRUG"
        },
        {
          "name": "Octreotide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "RADIATION"
        },
        {
          "name": "Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Modafinil & Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Sertraline",
          "type": "DRUG"
        },
        {
          "name": "IV Saline",
          "type": "PROCEDURE"
        },
        {
          "name": "Drinking Water",
          "type": "OTHER"
        },
        {
          "name": "Breathing Device",
          "type": "DEVICE"
        },
        {
          "name": "memantine",
          "type": "DRUG"
        },
        {
          "name": "Abdominal binder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DIETARY_SUPPLEMENT",
        "RADIATION",
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Satish R. Raj",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 150,
      "start_date": "1997-04",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-08",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00262470"
    },
    {
      "nct_id": "NCT00738023",
      "title": "Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Rosiglitazone",
          "type": "DRUG"
        },
        {
          "name": "Normal saline 0.9%",
          "type": "DRUG"
        },
        {
          "name": "Intralipid 20%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2004-03",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2014-12-30",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00738023"
    },
    {
      "nct_id": "NCT02335203",
      "title": "The Effect of Neoadjuvant DMPA on Glandular Cellularity in Women Awaiting Hysterectomy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Grade 1 Endometrial Endometrioid Adenocarcinoma",
        "Grade 2 Endometrial Endometrioid Adenocarcinoma",
        "Complex Atypical Endometrial Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Depot medroxyprogesterone acetate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Women and Infants Hospital of Rhode Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 76,
      "start_date": "2015-02",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2016-09-20",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02335203"
    },
    {
      "nct_id": "NCT04469179",
      "title": "Safety, Tolerability, and Pharmacokinetics of SAB-185 in Ambulatory Participants With COVID-19",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID-19",
        "SARS-CoV2"
      ],
      "interventions": [
        {
          "name": "SAB-185",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "SAb Biotherapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 21,
      "start_date": "2020-08-20",
      "completion_date": "2021-11",
      "has_results": false,
      "last_update_posted_date": "2021-10-26",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 3,
      "location_summary": "Miami Beach, Florida • Omaha, Nebraska • Sioux Falls, South Dakota",
      "locations": [
        {
          "city": "Miami Beach",
          "state": "Florida"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04469179"
    },
    {
      "nct_id": "NCT05873218",
      "title": "Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Labor"
      ],
      "interventions": [
        {
          "name": "Ephedrine",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2023-06-26",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05873218"
    },
    {
      "nct_id": "NCT04263181",
      "title": "AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Myeloid Leukemia",
        "Myelodysplastic Syndromes"
      ],
      "interventions": [
        {
          "name": "Peripheral blood draw",
          "type": "PROCEDURE"
        },
        {
          "name": "Bone marrow aspirate",
          "type": "PROCEDURE"
        },
        {
          "name": "Buccal swab",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2020-01-29",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04263181"
    },
    {
      "nct_id": "NCT06842771",
      "title": "Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Laparoscopic Adnexal Surgery"
      ],
      "interventions": [
        {
          "name": "Normal Saline (0.9% NaCl)",
          "type": "OTHER"
        },
        {
          "name": "Marcaine hydrochloride without epinephrine 0.5%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 96,
      "start_date": "2025-03",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06842771"
    },
    {
      "nct_id": "NCT01513200",
      "title": "Study to Assess the Pharmacodynamic Effects of Unfractionated Heparin (UFH) in Healthy Volunteers With and Without Bendavia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Unfractionated heparin (UFH)",
          "type": "DRUG"
        },
        {
          "name": "Bendavia",
          "type": "DRUG"
        },
        {
          "name": "Saline (0.9%, sterile, for infusion)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stealth BioTherapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 12,
      "start_date": "2012-01",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2012-04-19",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01513200"
    },
    {
      "nct_id": "NCT06369675",
      "title": "Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Erythema"
      ],
      "interventions": [
        {
          "name": "MOB015B",
          "type": "DRUG"
        },
        {
          "name": "0.2% SLS",
          "type": "DRUG"
        },
        {
          "name": "0.9% Saline",
          "type": "DRUG"
        },
        {
          "name": "MOB015B vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Moberg Pharma AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2017-10-19",
      "completion_date": "2017-11-14",
      "has_results": false,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Fair Lawn, New Jersey",
      "locations": [
        {
          "city": "Fair Lawn",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06369675"
    },
    {
      "nct_id": "NCT04415931",
      "title": "Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shoulder Osteoarthritis",
        "Cuff Tear Arthropathy",
        "Massive Rotator Cuff Tear"
      ],
      "interventions": [
        {
          "name": "Local infiltration analgesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Interscalene block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2020-08-15",
      "completion_date": "2022-03-13",
      "has_results": false,
      "last_update_posted_date": "2023-03-14",
      "last_synced_at": "2026-09-24T14:47:03.127Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04415931"
    }
  ]
}